Award Data

FIRST RF will lead the Phase II effort and will leverage the system architecture of the MAINLINE system and integrate multifunctional SiGe integrated circuits (ICs) developed by The University of California San Diego under the supervision of Prof. Gabriel Rebeiz. The SiGe devices developed during the Phase II effort will significantly reduce the power requirements of the MAINLINE system allowing f ...

Filoviruses, consisting of two major virus families including the ebolaviruses and marburgviruses (MARV and RAVV), cause periodic outbreaks of severe viral hemorrhagic fever with mortality rates as high as 90%. Since it is difficult to predict the species that would dominate future outbreaks, development of broadly protective therapeutics to prevent and manage future filovirus outbreaks is of high ...

Metallic additive manufacturing (AM) is an attractive technology for the production of lethality test articles due to the potential for significantly reduced lead time and manufacturing cost. However, in order to be effective in providing accurate lethality data, the properties of the AM material have to match closely the properties of conventionally manufactured alloys found in real threat target ...

Target detection and recognition is a challenging problem because of changes in appearance, viewing direction, occlusion and other covariates. Systems that can accurately and efficiently detect and track objects can provide several benefits in surveillance, monitoring and other applications. As part of this effort, we propose to develop a robust learning-based approach to detect, track and recogni ...

Abstract. LEXEO Therapeutics, LLC, is an early stage biotechnology company focused on using gene therapy technologies to protect vulnerable organs from oxidant stress. LEX01, the 1st LEXEO product, is a 1st in class, next generation gene therapy treatment for alpha 1-antitrypsin (AAT) deficiency, an autosomal recessive hereditary disorder associated with low serum levels of AAT. AAT (SERPINA1), a ...

This project will develop a Socially-Assistive Robot (SAR) to provide cognitive training, in the form of learning to play the piano, to improve cognitive functioning and reduce feelings of loneliness in socially-isolated older adults. The SAR will administer cognitive training via guided practice on a set of standard piano lesson tasks designed to reflect particular cognitive functions: memory, at ...

The DOE Office of Nuclear Physics (NP) seeks innovations that will advance our nation’s capability to perform nuclear physics research, and more specifically to improve DOE Nuclear Physics (NP) Facilities and the wider NP community experimental programs. For example, data acquisition (DAQ) for the Facility for Rare Isotope Beams (FRIB), currently under construction, will require considerable spe ...

The composition of atmospheric particulate matter (“aerosols”) strongly influences health and environmental impacts, but there exist few time-resolved, long-term records of particle-phase chemical composition due to lack of appropriate monitoring tools. Needed is an instrument that is robust, easy-to-operate, with automated calibrations and data reduction, to provide operationally-inexpensive ...

SIFT proposes Network Enforcement Using TRansactONs (NEUTRON) a dynamic fine-grained network enforcement policy design that captures network dependencies. NEUTRON closes the knowledge gap between mission needs and observed network traffic to increase mission network awareness. Then using that knowledge develops a revolutionary security enforcement policy based on network transactions. It reduces t ...

Cyber Risk Assessments for Threatened Environments (CRATE) is a system that produces actionable, mission-level alerts when anomalous behaviors indicative of cyber-attack are discovered within deployed mission-critical cyber-systems. CRATE is particularly relevant to deployment scenarios involving third-party infrastructure, such as deployment to a Platform as a Service (PaaS) provider or other clo ...