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STTR Phase II: Deep Learning Technology For The Microscopic Analysis Of Stained Cells Using Unbiased MethodsSBC: Stereology Resource Center, Inc Topic: BT
The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase II project is the development of software to help bioscientists analyze more tissue in less time and with higher accuracy and reproducibility. Currently, stereology studies require a trained technician to sit before a computer screen, making tedious manual counts (clicks) on hundreds to thousands of mic ...STTR Phase II 2019 National Science Foundation
SBC: UPSTATE PARTS & SUPPLY INC Topic: 09a
AHUs for residential HVAC systems typically use low-efficiency blower fans (evaporator side) and simple axial fans (condenser side), and the fan and the surrounding High Resistance Mediums (heat exchanger. filter, burner, etc.) are treated as stand-alone components during design optimization. With the recent introduction of high speed electronically commuted motors (high- speed ECM), it is now pos ...STTR Phase I 2019 Department of Energy
New Crystalline Silicon Module Architecture to Reduce Costs withImproved Manufacturability andDurabilitySBC: Creative Light Source, Inc Topic: 16a
Direct Solar in partnership with Colorado State University's Next Generation PV Center (NGPV) and H. B. Fuller Company will develop a new solar module architecture and manufacturing process optimized for crystalline silicon (c-Si) modules that significantly reduces manufacturing costs and improves reliability. The outcome of this program will be a new c-Si module design, streamlined manufacturing ...STTR Phase I 2019 Department of Energy
SBC: BETTERGY CORP. Topic: 17b
Enriching lithium from oilfield brines while performing desalination of the produced water can provide a solution that recovers valuable lithium from highly mineralized brine while at the same time making possible to reuse and recycle the treated waste water. State-of-the-art technologies for recovering lithium from oilfield brine include gravity separation, gas flotation, and flocculation. These ...STTR Phase I 2019 Department of Energy
SBC: Op-T-Mune, Inc Topic: NIAID
Type 1 Diabetes (T1D) affects an ever growing population. While this disease typically has been associated with juveniles, the disease in adult populations is rapidly increasing. The defining clinical component is insulin loss, which occurs because of sustained inflammation in the islets. At present there is no means to prevent or reverse insulin loss. A major inflammatory pathway in T1D that cont ...STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: LEXEO Therapeutics LLC Topic: NHLBI
Abstract. LEXEO Therapeutics, LLC, is an early stage biotechnology company focused on using gene therapy technologies to protect vulnerable organs from oxidant stress. LEX01, the 1st LEXEO product, is a 1st in class, next generation gene therapy treatment for alpha 1-antitrypsin (AAT) deficiency, an autosomal recessive hereditary disorder associated with low serum levels of AAT. AAT (SERPINA1), a ...STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
Targeting bacteria, the innate response of the middle ear to infection, and host-pathogen interactions, using topical and transtympanic applications for the treatment of otitis media.SBC: EARNANO LLC Topic: NICHD
Otitis media is a world wide disease primarily affecting the pediatric population under the age ofyearsIt is the most common reason for pediatric care visits and antibiotic therapyOver prescription and poorcompliance have led to a reduced susceptibility of bacteria to antibiotics andconsequentiallyto recurrent and chronic ear diseasesClearlythere is a compelling need to investigate alternative the ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: Periomics Care LLC Topic: NIDCR
Abstract Periodontitis is a common chronic inflammatory disease characterized by destruction of the supporting structures of the teeththe periodontal ligament and alveolar boneThe total prevalence of periodontitis in adults agedyears and older wasrepresenting aboutmillion adults agedyears and olderandin adults agedyears and older in the U SEpidemiological data confirm that diabetes is a major risk ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: POINT DESIGNS, LLC Topic: NICHD
The Point DigitA Ratcheting Prosthetic Finger UsingAdvanced Rapid Manufacturing Technology Project SummaryAbstract The goal of the proposed project is to develop and commercialize a purely mechanicalratcheting prosthetic fingerthe Point Digitwhichhas an industry leading strength to weight ratiocan be operated unilaterallyone handedoffers anatomical rotation and flexion around the patient s metacar ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: LEXEO Therapeutics LLC Topic: 400
AbstractLEXEO TherapeuticsLLCis an early stage biotechnology company focused on using in vivo gene therapy technologies to treat disorders of unmet medical needLEXEO is developing an in vivo gene therapy strategy as a preventative therapy to protect individuals with aldehyde dehydrogenaseALDHdeficiency from the high risk for esophageal cancerAs the next step in the development paththe goal of this ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health