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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Bacterial fermentation in skin microbiome as probiotics (Bfismp) against S. aureu

    SBC: Surface Bioadvances, Inc.            Topic: NIAMS

    DESCRIPTION (provided by applicant): Bacterial interference creates an ecological competition between commensal bacteria and pathogenic species. Like microbial competition via fermentation in a ripening fruit, bacterial interference via fermentation has been found in the deep-seated skin abscesses where is an anaerobic microenvironment, allowing bacteria to ferment carbohydrates to short-chain fa ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Topical application of heterologous protein-expressing Staphylococcus epidermidis for potential therapeutic treatment of skin diseases

    SBC: Azitra Inc.            Topic: NIAID

    PROJECT SUMMARY Current treatment options for a number of skin diseases generally aim for symptomatic relief and fail to address underlying pathophysiological changes leading to skin disease In the case of genetic mutations that cause loss of function mutations supplementation of the missing protein is a viable approach to treatment However delivery of functional protein to the target keratino ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Development of Optimized Endectocide-treated Bird Feed Formulations for West Nile Virus Control

    SBC: TDA RESEARCH, INC.            Topic: NIAID

    Project Summary Abstract Development of Optimized Endectocide treated Bird Feed Formulations for West Nile Virus Control STTR Phase I Application PIs Brady Clapsaddle TDA Research Inc Dr Brian Foy Colorado State University West Nile Virus WNV is the leading cause of domestically acquired arboviral disease in the United States resulting in significant disease and death every year in both ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Reagents to Create Large DNA Constructs in One Assembly Step

    SBC: FIREBIRD BIOMOLECULAR SCIENCES LLC            Topic: 100

    DESCRIPTION provided by applicant To many notably Craig Venter andquot synthetic biologyandquot means simply andquot synthesizing large amounts of DNAandquot This type of synthetic biology actually began in the andapos s when Caruthers introduced a phosphoramidite based solid phase DNA synthesis architecture This allowed ICI and the Benner group to synthesize complete genes encoding ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Beyond Screen Time: Developing an objective mobile media measurement tool

    SBC: OpenLattice, Inc.            Topic: NICHD

    PROJECT ABSTRACT Excessive digital media use has been linked with several adverse health outcomes in childrenincluding obesitydisrupted sleepexternalizing behaviorand executive functioning deficitsbut measurement tools have not kept pace with the advancements in digital technology now used in most American householdsFor examplemost American families with young children now own a smartphoneor table ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Simultaneous kinetic analyses of neuronal connectivities

    SBC: CIENCIA INC            Topic: 101

    DESCRIPTION provided by applicant Aberrant neuronal connectivity is associated with a number of neuropathological and neuropsychiatric diseases disorders Inefficient developmental connectivity misdirected connectivity or disrupted and degenerated connectivity can account for losses of normal neuronal communication and subsequent losses of mental or physical health Altered expression of axon ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. A noninvasive optical imaging of retinal amyloid beta deposits in AD patients

    SBC: NEUROVISION IMAGING, LLC            Topic: NIA

    DESCRIPTION (provided by applicant): Alzheimer's disease (AD) is a progressive and invariably fatal degenerative dementia and the most common form of dementia that currently affects over 5 million Americans. The quality of life and economic costs are significant with estimated U.S. health care payments of over 200 billion in 2012, plus unpaid care by over 15 million Americans that is valued ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  8. Single Cell chemical Imaging via nanoscale IR ablation- Mass Spectromety

    SBC: Anasys Instruments Corp.            Topic: NIGMS

    DESCRIPTION (provided by applicant): The goals of this project are twofold: a) to develop a new technique for nanoscale Mass spectrometry imaging based on AFM based tip enhanced IR ablation (nanoIR-MS). b) to apply this technique towards the application ofSingle cell imaging. Information on the chemical composition within a cell has implications in the understanding of cell metabolism, division, d ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Characterization of Exudative Macular Degeneration and Diabetic Retinopathy Using

    SBC: VISDEX CORP            Topic: NEI

    DESCRIPTION (provided by applicant): Since its first use in the retina in 1961, fluorescein angiography (FA) has been the gold standard for objective characterization of retinovascular disease (e.g. diabetic retinopathy, retinal vein occlusions, and choroidal neovascularization associated with age-related macular degeneration (AMD)). Despite its widespread use, FA is costly, invasive, and time con ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  10. Mid-IR LIDAR for Detecting Volatile Organic Compounds

    SBC: Princeton Technology Advisers Company Inc.            Topic: NIEHS

    DESCRIPTION (provided by applicant): This project addresses the need for the development of field deployable, sensors which provide real-time quantitative measurements of Volatile Organic Compounds - airborne pollutants that are injurious to human health. In this particular case, benzene, formaldehyde and 1,3-butadiene. These three compounds have been identified as top cancer risk air pollutants T ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
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