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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Denaturation-Free DNA Target Enrichment and Direct Sequencing of Large Chromosomal Segments
SBC: GENERATION BIOTECH, LLC Topic: 172SummaryThird generationlong read sequencing technologies are increasingly sought after for the analysis of difficult genomic regionssuch as the major histocompatibility complexMHCthe human leukocyte antigenHLAloci and genomes of cancerspathogens and viral insertionsas well as plant and animal genomesSuch methods provide researchers with more contextual informationenabling analysis of highly comple ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
High-Throughput Spheroid Screening Platform
SBC: BennuBio Inc Topic: 400PROJECT SUMMARYThis proposal will develop the High-Throughput Spheroid Screening Platform (HTSSP) to create an entirely new tool to study cell-cell interactions and microenvironmental stresses that occur in tissues and tumors. Such interactions are critical in the pharmaceutical response of cells within tissues, but current methods do not allow high throughput screening (HTS) of cellular responses ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Laboratory Bench-Top EXAFS with STJ Spectrometer
SBC: STAR CRYOELECTRONICS, LLC Topic: 400PROJECT SUMMARY Extended X-ray absorption fine structure (EXAFS) spectroscopy is a technique that gives element-specific structural and chemical information about molecules. An enormous advantage of EXAFS spectroscopy is that it is readily applied to many different kinds of sample, including, solutions, powders, slurries, and animal tissues. Current EXAFS instruments require bright X-ray beams fro ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Micronized salsalate in a parenteral formulation is a safe and effective analgesic for acute postoperative pain management
SBC: RH NANOPHARMACEUTICALS L.L.C. Topic: 101SUMMARY: The White House has initiated an aggressive campaign to combat the current opioid crisis that is affecting all levels of the American way of life. The opioid crisis has emerged from multiple fronts. Among these various fronts, the continued use of opioids in the post-operative area is a growing addiction risk. Current post- operative pain management utilizes a multimodal pain management s ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
PreImplantation Factor plus hypothermia to treat neonatal brain injury
SBC: BioIncept, LLC Topic: NICHDABSTRACTPerinatal hypoxic ischemic encephalopathyHIEaffectstoinfants per everybornMortality from HIE can be up toand approximatelyof survivors suffer significant longterm disability including cerebral palsyepilepsyand developmental disordersDamage during the acute phase of HIE is caused by a deficit in oxygen and glucose in the brainHoweverincreasing evidence indicates that secondary and tertiary ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Long-term therapeutic effects of synthetic bryostatin-1 in advanced AD without memantine
SBC: SYNAPTOGENIX, INC. Topic: RProgram Director/Principal Investigator (Last, First, Middle): Miao-Kun Sun Project Summary/Abstract The importance of memory impairment and dementias, including Alzheimer’s disease (AD), as a global priority has been well recognized. Many compounds that target AD pathologies have been developed preclinically but have failed in clinical trials, mostly for the lack of therapeutic efficacies.Neuro ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Rapid and Effective Localized Neurovascular Cooling Using the Khione Insulative Catheter
SBC: Tom L Merrill Topic: 101Project Summary Stroke is the 5th leading cause of death and number one cause of adult disability in the United States. The primary goal of acute ischemic stroke (AIS) treatment is quickly restoring blood perfusion. However, studies have shown that this return of blood flow, while necessary, can also cause damage to local tissue leading to poor patient outcomes. Therapeutic hypothermia (TH) has be ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Performance Evaluation of a non-Degradable Synthetic Device for Chondral and Osteochondral Defects of the Knee
SBC: Hydro-Gen LLC Topic: NIAMSInjury to joints can lead to painful defects in articular cartilage and the underlying bone, which adversely affect the function and biological health of the entire joint. Current solutions for cartilage (chondral) and cartilage-and- bone (osteochondral) defects, are unreliable, are technically challenging, and often require multiple procedures. A surgeon-engineer-biologist team at Hospital for Sp ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Screen molecules modulating MOR trafficking with a newly developed MOR/14-3-3 bioassay.
SBC: BIOINVENU CORPORATION Topic: NIDASpecific AimValidate the MORLinkLight assay with a pilot HTS to identify molecules modulating MOR traffickingSignificanceThe current crisis of opioid use disordersOUDsand opioid overdose deaths in the United States urgently demands safer and better therapeuticsTo develop better and safer therapeutic agents for the treatment of OUDsfirst and foremost is to have new bioassays which are different fro ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Malarial Retinopathy Screening System for Improved Diagnosis of Cerebral Malaria
SBC: VisionQuest Biomedical Inc Topic: NIAIDSummary Cerebral malaria (CM) is a life-threatening clinical syndrome associated with malarial infection. Annually, malaria affects more than 200 million people and claims the lives of over 440,000 people worldwide, mostly African children. As a consequence of the high incidence of CM, it is often misdiagnosed for other pathologies with similar symptoms, leading to a high false positive rate for C ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health