Award Data

DESCRIPTION (provided by applicant): A novel enhanced dynamic range camera (EDRaC) is proposed for greatly improved fluorescence detection in proteomics. In the longer term the EDRaC can improve the performance of a wide range of biomedical applications us ing fluorescent microwell plate reading and/or microscopy. The initial emphasis will be to develop, demonstrate, and apply the technology to mu ...

Improved observations of the battlespace are of key and growing importance in today’s combat environment. UAVs are making key contributions in this area, and sensor improvements are a key part of increasing UAV capabilities. However, all sensors are subject to degradation under detrimental environmental conditions. Adding a sensor system to UAVs that enables the real-time identification and a ...

DESCRIPTION provided by applicant Specific information about the state of second messengers in drug signaling pathways is key to understanding the mechanism of a drug within the cell The largest class of drug targets is the G Protein Coupled Receptor GPCR and over of all prescription pharmaceuticals target a GPCR These proteins are the focus of many drug discovery programs because they ...

AN OBJECTIVE OF THIS PROJECT WILL BE THE DEVELOPMENT OF NEW AND NOVEL THERMOPLASTIC POLYMER ALLOYS WITH HIGH RESISTANCE TO ALL KNOWN HAZARDOUS CHEMICALS. A FURTHER OBJECTIVE WILL BE TO CROSSLINK INDIVIDUAL POLYMERS IN THESE ALLOYS TO FORM NON-MELTING INTERPENETRATING POLYMER NETWORKS (IPN'S) WHICH WILL EXHIBIT GREATER RESISTANCE TO HAZARDOUS CHEMICALS THAN THE THERMOPLASTIC ALLOYS FROM WHICH THEY ...

Existing OAML-approved active acoustic models are under continuous evolution to take advantage of new theoretical and numerical developments and more powerful computational resources. These models are supported by OAML-approved environmental databases that are also constantly updated to accommodate the newly developed models and recent measurements throughout the world. The databases that describe ...

DESCRIPTION (provided by applicant): Myomics, Inc. has developed High Content Drug Screening (HCS) technology for in vitro testing of compounds which alter contractile forces generated by miniaturized tissue engineered organs (Myo-Force Assay SystemTM, MFA STM). Myomics' 3-D tissue/force sensor composite is capable of long term studies (1-4 weeks) and provides force as well as electrophysiological ...

This NIST Phase 1 SBIR effort will demonstrate the feasibility of low noise single photon up conversion using KTiOPO4 (KTP) or LiNbO3 (LN) or Stoichiometric LiTaO3 (SLT) periodically poled waveguides and an 1800nm pump for a high efficiency single photon detector. The key innovation is using low noise periodically poled waveguides with a long wavelength (1800nm) pump leading to higher efficiency s ...

ABSTRACT: To provide reliably secure communications, development of practical quantum optical devices for ground-to-space quantum key distribution is a necessity. The overall goal of this Air Force effort is to develop and deliver a single photon source based on heralding to indicate when a photon has been generated. The proposed device will produce single photons on demand with high efficiency ...

AdvR, Inc. proposes the development of a highly efficient, fiber pigtailed, waveguide-based UV frequency converter module. This UV module will be an important element in future NASA sponsored Doppler lidar and High Spectral Resolution Lidar (HSRL) aerosol missions. The key innovation is the use of dual-element periodically poled waveguides embedded in a nonlinear optical substrate. This innovat ...

Geologic carbon sequestration has the potential to store a century¿s worth of anthropogenic carbon dioxide production. However, this solution will require numerous large underground reservoirs that may extend over hundreds of square kilometers and an extensive network of pipelines, some of which will be on the order of hundreds of kilometers long. Consequently, very large areas will need to b ...