You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Create Ultralong DNA Constructs in One Assembly Step

    SBC: FIREBIRD BIOMOLECULAR SCIENCES LLC            Topic: 400

    Create Ultralong DNA Constructs in One Assembly Step Firebird Biomolecular Sciences LLCSteven ABenner Foundation for Applied Molecular EvolutionShuichi Hoshika AbstractFrost andampSullivan found aglobal market for DNA oligos at $million$million for genesPrivate investment in DNA synthesis companies like TwistGinkgoand DNA Script give collective valuations of several billion dollarsFederal public i ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Novel radiometry-guided ablation catheter to treat resistant hypertension or CKD

    SBC: Symple Surgical Inc            Topic: R

    PROJECT SUMMARY Increased renal sympathetic activity is a causal pathogenetic mechanism of both cardiovascular hypertension and progressive loss of renal function in patients with chronic kidney diseaseCKDIn millions of patients with resistant hypertensiondependable thermal disruption of targeted renal sympathetic nerves can reduce blood pressure and ultimately prevent heart diseasestroke and kidn ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. 4D Acoustoelectric Cardiac Imaging for Fast and Accurate Mapping of Arrhythmias

    SBC: ElectroSonix LC            Topic: NHLBI

    Abstract Despite global success of interventional cardiac surgery for treatment of arrhythmias, electroanatomical mapping (EAM) of the heart has significant drawbacks. The procedure is slow and prone to registration errors, largely ineffective for treating transient arrhythmias, such as ventricular tachycardia, and exhibits relatively poor spatial resolution. With only a 50% success rate for first ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Development and evaluation of an internet based adaptation of the New Beginnings Program for divorced parents

    SBC: Family Transitions- Programs that Work, LLC            Topic: NICHD

    PROJECT ABSTRACT The proposed research builds on a successful Phase I SBIR grant to develop and test a web based version of a parenting after divorce group interventionthe New Beginnings Programwhich has been shown in two randomized trials to reduce youthsproblem behaviors and enhance their developmental competencies in theyear period after their parents participatedThe proposed web based format w ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Overcoming Isoniazid Resistance in Tuberculosis with New Chemical Entitites

    SBC: SpinCeutica, Inc.            Topic: NCHHSTP

    Isoniazid resistance is a major problem worldwideespecially the high level resistance caused by ST KatG mutationWe have found a stable isotope substitution improves activity against this resistant strainwhile others have used long acyl hydrazides that also improve activityWe therefore hypothesize that combining long acyl chain hydrazides to drive ST KatG binding with our MIE enhancedacylC INH warh ...

    SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  6. SnapCap: a device to decontaminate central venous catheters (CVC) with 5 snaps

    SBC: Contech Medical, Inc.            Topic: NICHD

    Project Summary Abstract We propose a new approach to the decontamination of central venous catheters and the prevention of central line associated bloodstream infectionsCLABSIan important healthcare associated infectionCLABSIs cost the US healthcare system approximately $billion annuallyPronovostNEJMAdditionallyCLABSIs can be life threateningespecially in the very young and critically illEven whe ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Dual View Endoscopy for Colonoscopy

    SBC: Omniscient Imaging, Inc.            Topic: 102

    AbstractAn estimatedmillion colonoscopies are performed annually in the US at a cost of about $Bhowever current colonoscopes with forward vision fail to detectof precancerous polypsOverof the missed polyps are located on or behind numerous folds in the colon where they are hidden from the sight of a forward view colonoscopeIn this research proposalwe propose to complete our development of an imagi ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Origami Nanoprobes for Large-Scale Single-Cell Analysis of Lymphocytes

    SBC: Gemneo Bioscience, Inc.            Topic: 100

    Project Summary Abstract Next generation sequencing platforms have revolutionized modern approaches for understanding a wide variety of biological processesincluding immune responses and cancerHoweverincreasing evidence shows that the diversity of the cells involved in these processes has important implications for understanding biologic outcomesFor instancethe diversity of T cell receptors on lym ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Development of Spleen Tyrosine Kinase (SYK) negative allosteric modifiers for therapeutic intervention in Alzheimer's disease.

    SBC: ARCHER PHARMACEUTICALS, INC.            Topic: NIA

    Pathological hallmarks of Alzheimerandapos s diseaseADinclude extracellular deposits of Apeptidesintraneuronal aggregates of abnormally phosphorylated tau protein and neuroinflammationMost proposed AD disease modifying therapies have focused on strategies that reduce brain Aamyloid or tau pathological accumulationHoweversuch approaches have been unsuccessful in late stage AD clinical trials and ma ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. A Phase 2b Clinical Trial to Study the Efficacy of Longeveron Mesenchymal Stem Cells (LMSCs) to Treat Aging Frailty

    SBC: Longeveron LLC            Topic: NIA

    Aging Frailty is a biologically driven geriatric syndrome of multisystem physiological decline that is distinct from normal aging and disproportionately increases vulnerability to adverse clinical outcomesFrailty has an overall prevalence ofof thoseyears and olderand there is growing awareness in the geriatric community to diagnose and treat this conditionas it is not an inevitable consequence of ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government