Award Data

"This project proposes to cost effectively prepare scFv or Fab antibody fragments that have been modified to site-specifically incorporate stable linkable moieties that will allow their conjugation to reporter molecules and surfaces without comprising thebiological function of the binding site of the antibody fragment. The ready availability of technologies to prepare these antibody fragments wit ...

The objective of the proposed program is to develop and demonstrate a robust andefficient optical parametric oscillator for converting the output of a solid state,1.06 micron laser to the 8-12 mmicron band for application to laser standoff chemicalsensors. The converter will be based on nonlinear crystals that have much higherdamage threshold than the conventional AgGaSe2 type and efficiency will ...

The objective of the Phase II program is to develop, demonstrate, and integrate a robust and efficient optical parametric oscillator wavelength converter with the Manportable Sensor developed under a prior program. The converter will be based on robustnonlinear crystals in novel intracavity and extracavity resonator configurations that will provide improved conversion efficiency. The effort will i ...

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Development of a monolythic carbon dioxide scrubber material for us e in closed circuit underwater breathing apparatus. The project will specifically test water tolerance and absorbtion performance in closed breathing loop environments.

"The early genomic responses of human peripheral blood mononuclear cells (PBMCs) to in vitro infection with specific microbial pathogens will be assessed by DNA microarray technology. Host gene expression "signature" to microbial pathogen exposure anddistinct host responses will be characterized. Detailed in vitro studies will permit forecasting/predicting expected early molecular markers of in ...

Low-cost, high-resolution, field-portable chemical analysis systems are needed to meet critical detection requirements for environmental monitoring and sampling, and for the specific problem of chemical agent battle-field detection and nonproliferation monitoring. New technologies are needed to bring lab-quality performance to the field. An innovative ionization method is proposed that provides ...

During the Phase I, a lightweight, multilayer coating will be deposited onto copper wire and the wire woven into a mesh. The coating provides a high level of EM shielding, including magnetic shielding, EMP shielding and powers line filtering. The woven mesh will form a flexible shield with similar properties. Draped over existing equipment or used to line the walls, it will provide temporary and ...

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The purpose of this project is to develop user-friendly mission planning and rehearsal tools for a low-cost PC based parachute maneuvering simulator. The current version of this simulator has a head-mounted display (virtual reality) and high resolution, textured graphics. It is in use at several military installations for teaching and practicing flight control, navigation and equipment malfuncti ...