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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A High School Program for Preventing Prescription Drug Abuse

    SBC: NATIONAL HEALTH PROMOTION ASSOCIATES, INC            Topic: NIDA

    ABSTRACT A High School Program for Preventing Prescription Drug Abuse This Fast Track SBIR proposal is designed to address the critical need for an effective primary prevention approach for prescription drug abuse PDA an urgent public health crisis in the United States Deaths from prescription drug overdoses have more than tripled in the past years and the abuse of prescription opioids has ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Comprehensive Near Patient Assessment of Severe Hypoglycemia in Newborns Using Low Blood Volume

    SBC: Baebies, Inc.            Topic: NICHD

    ABSTRACT Comprehensive Near Patient Assessment of Severe Hypoglycemia in Newborns using Low Blood Volume Fast Track SBIR Hypoglycemia is the most common metabolic disorder in newborns and places the neonate at increased risk of seizures and permanent brain injury The etiology of severe neonatal hypoglycemia which affects around newborns each year in the U S is complex with unde ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Cardiac Monitor for VA ECMO Pediatric and Neonatal Patients

    SBC: TRANSONIC SYSTEMS, INC.            Topic: NHLBI

    PROJECT SUMMARY ABSTRACT Venoarterial Extracorporeal Membrane Oxygenation VA ECMO is a way to provide cardiac and pulmonary support to patients without other alternatives This form of life support is vital to pediatric and neonatal patients As with any life support there are serious complications that occur These complications including bleeding thrombosis and infection become more frequen ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Ultrasound Based Device to Guide Treatment of Graft Versus Host Disease Using Skin Elasticity as a Biomarker

    SBC: Microelastic Ultrasound Systems, Inc.            Topic: 102

    Ultrasound Based Device to Guide Treatment of Graft Versus Host Disease using Skin Elasticity as a Biomarker ABSTRACT Sclerotic chronic graft versus host disease cGVHD develops in of allogenic Human Stem Cell Transplant HCT recipients and is associated with significant morbidity and mortality GVHD is treated with immunosuppression which puts patients at severe risk of infection ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. AML MutationCounter a tool to detect residual and recurrent leukemia

    SBC: Asystbio Laboratories, LLC            Topic: 102

    Abstract AsystBio LLC proposes to market a molecular tool kit called AML MutationCounter to count somatic mutations in genes that contribute to the development of acute myeloid leukemia AML We have developed a set of reagents and computer programs for application of next generation sequencing to count AML gene mutations The tool kit is versatile and can be used with either of the two major DNA ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. E training of Inmate Peer Caregivers for Enhancing Geriatric and End of life Care in Prisons

    SBC: KLEIN BUENDEL, INC            Topic: NIA

    The US has the highest incarceration rate in the world imprisoning people per The older adult segment of the prison population has more than tripled since and their health issues are common to free people who are years their senior Inmates over the age of have a death rate that is times that of prisoners aged US prison systems are facing sharply increased dema ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. A novel product for tendinopathy treatment

    SBC: NEW YORK R&D CENTER FOR TRANSLATIONAL MEDICINE AND THERAPEUTICS, INC.            Topic: NIA

    Project Summary This study aims to prove the concept and feasibility that TendonCure extracellular vesicles that contain signaling molecules i e exosomes secreted by mesenchymal stem cells i e tendon stem progenitor cells TSPCs or adipose derived stem cells ADSCs from individual patients donors cultured on a novel scaffold exert therapeutic efficacy on tendinopathy when injected into ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Screening for the autoimmune component of multiple sclerosis

    SBC: Op-T-Mune, Inc            Topic: NIAID

    Multiple Sclerosis is an inflammatory neurodegenerative disease with autoimmune components that exacerbate and potentially initiate the disease Diagnosis is invasive time consuming relatively expensive and extremely difficult In fact no clear diagnostic test yet exist A major concern is that MS symptoms are identical to the symptoms of numerous other neurologic diseases OND as well as some ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Creation of animal models of mitochondrial DNA disease for translational research applications

    SBC: Enzerna Biosciences LLC            Topic: 400

    Mitochondria are the principal generators of cellular ATP by oxidative phosphorylation which links electron transport via Complexes I through IV to production of ATP via ATP synthase Over pathogenic human mitochondrial DNA mtDNA mutations associated with diseases ranging from cardiomyopathy to juvenile blindness have been identified Collectively millions are affected by mtDNA disease fo ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Microfabrication based Biomimetic Approach for In Vitro Red Blood Cell Maturation

    SBC: Simpore Inc.            Topic: NHLBI

    Abstract The overall goal of this proposal is to develop systems for efficient ex vivo maturation of functional human red blood cells RBCs which holds tremendous potential for addressing supply bottlenecks for delivering new therapeutic options to chronically transfused patients with severe alloimmunization and for novel strategies for delivering therapeutics via engineered RBCs No approaches ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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