Award Data

Biological agents pose high threats, because they are invisible and odorless and a relatively small amount can infect a large population when released in a densely populated area. For the same reasons, assuring safety after cleaning decontaminated sites c

Aflatoxins B1 (AFB1) are fungal produced mycotoxins that are present in food supplies and are strongly associated with increased risk for thedevelopment of hepatocellular carcinoma. Currently, there are no known countermeasures to selectively mitigate AFB1 toxicity. To meet thischallenge, we successfully validated a Phase I proof-of-concept study to harness the microbiome extracts of scavenging ma ...

Raman spectroscopy is a highly effective non-contact laser remote sensing method for detecting and identifying chemicals in every-day field environments. Raman spectroscopy is particularly suited for detecting trace surface contaminants that may indicate the presence of explosives, harmful chemical or biological agents. Contemporary systems, such as the vehicle mounted Joint Contaminated Surface D ...

The overall goal of the SBIR Phase II program is development, fabrication, and demonstration of a fully integrated graphene-based sensor capable of detection of different types of chemical agents in the vapor phase with better than parts per billion (ppb) sensitivity and a high degree of specificity. It should also exhibit a reversible function of the sensing element. The program will synergistica ...

We propose an Acousto-Optic Tunable Filter (AOTF) Spectropolarimetric Imaging System for Enhanced Standoff Chemical Detection at Long Wave Infrared (LWIR) wavelengths. This work entails development of suitable LWIR material, design of the LWIR AOTF, and design of the hyperspectral imaging sensor using a focal plane array. Currently, there is no technologically mature, commercially available mater ...

This Phase II SBIR proposal responds to a CBD need for improved Acoustically Enhanced Impaction (AEI) air purification in support of low pressure drop filtration. Prior to the SBIR Phase I effort, a first generation/benchmark (AEI) system developed by Applied Research Associates, Inc. (ARA) demonstrated AEI functionality and the potential to significantly reduce the annualized operation filtration ...

Physical Science Inc. (PSI) will develop a new approach to chemical vapor detection based on a novel open-path sample cell design. The PhaseI system level model predicts SNR supporting a probability of detection of 95% and a MTBFA of 168 hours for all relevant CWAs and TICs at the10 minute negligible MEG level at a 20 s measurement time. In addition to robust detection, the system design can provi ...

Protein manufacturing is of paramount importance to chemical and biological defense applications. Existing protein purification methods primarily rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermeasures to chemical and biological threats. To overcome these limitations, the overall goal of th ...

ARAI auto-injector platform was developed from the ground up to meet the DoD requirements for a Next Generation auto-injector, and offersimproved Human Factors, improved drug stability, extremely robust, glass free construction, and versatility to accommodate a broad range oftreatments and treatment combinations, in terms of dose volumes, drug formats including wet, wet-wet, and wet-dry combinatio ...

We propose to develop low cost Long Wavelength Infrared Focal Plane Arrays (LWIR FPAs) using colloidal quantum dots (CQDs) of mercury telluride (HgTe). In Phase I, QDs in the size range of 20-25nm (corresponding to cutoff wavelength of 8 to 12 microns) w...