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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. improving Cas9 mediated homologous recombination in pluripotent stem cells

    SBC: APPLIED STEMCELL, INC.            Topic: 200

    DESCRIPTION provided by applicant Gene correction therapy is one of the most important application directions in regenerative medicine Scientists are exploring various approaches to introduce targeted mutations corrections to pluripotent stem cells PSCs to establish disease models and or to develop therapeutic agents Emerging technologies such as Zinc Finger Nucleases ZFNs Transcription ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications

    SBC: GENECAPTURE, INC.            Topic: CBD15C001

    The modern warfighter faces the constant threat of endemic infections, multi-drug resistant bacteria and Biological Warfare Agents. In order to provide accurate front-line treatment that will curtail the overuse of antibiotics, a rapid and robust molecula

    STTR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  3. Integrated Computational Material Engineering Approach to Additive Manufacturing for Stainless Steel (316L)

    SBC: SENVOL LLC            Topic: N16AT022

    Additive manufacturing (AM) will reduce the delay times required in producing Naval parts that are no longer stocked. However, rapid qualification of parts is still a challenge when a limited number of components are required. To fully exploit the potential advantages of AM, a means of accurately addressing the reliability of AM components is required. By simulating the entire design-build-operati ...

    STTR Phase I 2016 Department of DefenseNavy
  4. Integrated Computational Material Engineering Tool Set for Additive Manufacturing of Stainless Steel (316L)

    SBC: QUESTEK INNOVATIONS LLC            Topic: N16AT022

    In this Phase I STTR program, QuesTek Innovations, a leader in the field of integrated computational materials engineering (ICME) teaming with Prof. W.E. King from Lawrence Livermore National Laboratory (LLNL) as QuesTeks academic partner, proposes expand the computational Materials by Design technology by developing an Integrated Model Toolkit that enables the modeling of AM process by predicting ...

    STTR Phase I 2016 Department of DefenseNavy
  5. Jamboxx: Interactive Respiratory Therapy through Music and Gaming

    SBC: My Music Machines Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant The goal of this project is to develop a novel device for respiratory therapy that uses interactive gaming and music to encourage patient compliance In order to maintain pulmonary health many post operative surgery patients as well as people with quadriplegia and other spinal cord injuries high level motor neuron diseases such as amyotrophic lateral sclerosi ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Large-scale Entity Linking and Disambiguation with DeepDive

    SBC: CLEARCUT ANALYTICS, INC            Topic: N16AT016

    DeepDive is a system for extracting relational databases from dark data: the mass of text, tables, and images that are widely collected and stored but which cannot be exploited by standard relational tools. If the information in dark data --- scientific papers, Web classified ads, customer service notes, and so on --- were instead in a relational database, it would give analysts access to a massiv ...

    STTR Phase I 2016 Department of DefenseNavy
  7. Maximizing cancer synthetic lethality using dual PI-3K/PARP inhibitors

    SBC: SignalRx Pharmaceuticals Inc.            Topic: NCI

    PARP inhibitors PARPi are particularly efficacious in tumors deficient in the BRCA tumor suppressor genes but of limited activity in BRCA competent tumors There is an unmet medical need to develop targeted therapeutic agents which will augment PARPi activity for BRCA wild type cancers and to increase chemo radiosensitivity in these malignancies BRCA proteins are essential components ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Memory Lane: A neuro-exergame to mitigate cognitive decline in later life

    SBC: 1ST PLAYABLE PRODUCTIONS LLC            Topic: NIA

    DESCRIPTION provided by applicant st Playable Productions and Union College propose to develop a commercializable product combining physical exercise and cognitive activities through interactive gaming on a stationary bicycle to help prevent cognitive decline and dementia in older adults The Interactive Physical and Cognitive Exercise System iPACES developed by Union Collegeandapos s Health ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Mitochondrial TAT-DNA repair proteins for treatment of insulin resistance

    SBC: EXSCIEN CORPORATION            Topic: NIDDK

    DESCRIPTION provided by applicant Insulin resistance IR also known as metabolic syndrome is tied to obesity and is associated with numerous modern health problems including the growing problems of type diabetes and cardiovascular disease The growing health economic and social burdens of these conditions calls for the need to develop drug treatments for IR We know from multiple lines of ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Mobile Augmented Screening Tool to Increase Adolescent HIV Testing and Linkage to Care

    SBC: Digital Health Empowerment, Inc            Topic: NICHD

    DESCRIPTION provided by applicant Adolescents face combined problems of increased HIV risk infrequent testing inconsistent linkage to care and a lack of prevention related knowledge We propose to address this by developing a Mobile Augmented Screening MAS tool that will increase youth HIV testing through the use of a tablet based intervention in clinica settings and then use text message ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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