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SBC: CORAM TECHNOLOGIES INC Topic: 400
Summary Abstract Out of hospital cardiac arrest affects overpeople in the U Sannuallybut onlysurviveBystander cardiopulmonary resuscitationCPRimproves survivalbut rates of training in the U Sare lowIt is recently required by law inU Sstates that high school students learn CPRHoweverthere is great variability nationwide in howby whomand when students are taughtAdditionallycurrent methods of teachin ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: L2 DIAGNOSTICS LLC Topic: NIAID
PROJECT SUMMARYMalaria is one of the world’s major public health threats. The disease is transmitted when an infected female Anopheles mosquito, while probing for a blood meal, injects saliva together with Plasmodium sporozoites into the skin of the vertebrate host (1, 2). To date, a highly effective, safe and FDA-approved human vaccine against malaria has not been developed. The most establishe ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: AUSCULTECH DX LLC Topic: NHLBI
PROJECT SUMMARY The overall goal of the proposed research and technology transfer effort is to develop a low-cost, point-of-care, mobile device-based technology for automated identification of Stillandapos;s murmur, the most common innocent (benign and harmless) heart murmur of childhood. This novel technology could reduce the current rate of over half a million children unnecessarily referred to ...STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
Integrated Microbial Screening and Antimicrobial Susceptibility Test on Microfluidic Digital Array for Diagnosis of Urinary Tract InfectionsSBC: Combinati Incorporated Topic: NIAID
Abstract COMBiNATi will work with Stanford University to bring the world s first integrated ID AST UTI diagnostic platform to the market by combining COMBiNATi sone clickcost effective dPCR platform with Stanford s pathogen identificationIDHRMA algorithm for broad detectiondeep characterization and absolute quantification of UTI pathogensBy the end of the Phaseprojectwe will deliver the prototype ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: BEACON TECH INC Topic: R41
PROJECT SUMMARY This proposal develops a novelartificial intelligenceAIenabledmobile treatment delivery method that fulfills the need for a robustsecuretechnology based peer support platform to support patients with opioid use disordersOUDsThe majority of individuals with OUDs in the United States do not receive any formal substance use treatmentand growing evidence suggests that many OUD patients ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: CFD RESEARCH CORPORATION Topic: DTRA14B004
Terrorist use of radioactive nuclear materials via nuclear and/or radiological dispersion devices (dirty bombs) is a serious threat. Therefore, it is crucial to detect proliferation of nuclear material. Critical challenges include: (a) high sensitivity detection of signature emissions from radioactive isotopes, and (b) cost-effectiveness for deployment of sensor networks across large storage facil ...STTR Phase II 2019 Department of DefenseDefense Threat Reduction Agency
SBC: NeoVative, Inc. Topic: 400
“Code blue” is the signal used in hospitals to call for an immediate cardiopulmonary resuscitation (CPR) following a cardiac or respiratory arrest. Reviewing the performance of the “code blue team” is a cornerstone for improving outcomes. The current standard of using handwritten records on a paper “code sheet” does not allow measurement of key quality indicators and is subject to huma ...STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: L2 DIAGNOSTICS LLC Topic: NIAID
PROJECT SUMMARYZika virus, an emerging flavivirus, is associated with severe clinical outcomes, including Guillain-Barré syndrome and birth defects. Transmission of Zika virus is primarily mosquito- borne. Mosquito salivary proteins are known to enhance infectivity and pathogenesis in Zika, dengue and West Nile viruses by modulating immune responses. This proposal seeks to develop a novel vaccine ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: SCICRUNCH Topic: 300
Project SummaryOne of the most glaring yet easily addressable gaps in our current scientific workflow and publication system is improving the way that methods are reportedin particularthe lack of key methodological details necessary for interpreting and reproducing a studyMost authors continue to cite the name of the reagentlike an antibody using the vendorand the city where the vendor is locatedb ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: GENNEXT TECHNOLOGIES, INC. Topic: 400
The importance of large protein drugsbiopharmaceuticalsand their generic counterpartsknown as biosimilarshas created a need for improved analytics to facilitate biopharmaceutical research and to combat adverse drug reactionsThe recombinant protein expression process is inherently prone to low level errors resulting in sequence variants caused by amino acid misincorporationwhich are observed in bot ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health