Award Data

Chemical warfare agents such as the lethal nerve agent soman are a major source of risk to military personnel. Currently, pyridostigmine bromide (PB) is the only FDA-approved pretreatment to counteract the effects of soman. The rationale behind PB administration is that it acts as a “temporary” inhibitor of AChE. This precludes nerve agents from irreversible inactivation of AChE, thereby mitig ...

To address the CBD’s need for real-time analytical technology for multicomponent vapor identification and quantification, Physical Optics Corporation (POC) proposes to continue the development of a new Photoacoustic Gasses Optical Detector and Analyzer (PAGODA) autonomous, network-enabled photoacoustic spectrometer (PAS) for the correlation, analysis, and identification of measured spectra. In t ...

With the advent of high-density low-power sub-20nm technology processes and circuits with tens-of-billions of transistors, radiation-induced single-event effects present a new set of design challenges for terrestrial applications. Developing reliable single-event effect resilient microelectronics in these modern technology nodes is a resource and time-intensive endeavor that further requires valid ...

Over 820 million Indians, about 65% of its population, cook on polluting open fires, causing ~1 million premature deaths annually. Fifty million households have no electricity. The Power Stove is a household energy solution combining clean cooking and reliable, ondemand power. Clean combustion and thermoelectric power technology, make it a high performance, user desirable solution based on low cos ...

Discharging nutrients such as phosphorus and ammonia to surface waters can have far reaching health and environmental impacts, including the formation of toxic algae blooms, eutrophication, and loss of water_x000D_ quality. The wastewater industry has a significant need for high-efficiency nutrient removal technologies. However, current nutrient removal treatment technologies can be costly and in ...

Surgical trainingrequires an understanding of the human body’scomplex3-dimensional anatomical structures and thespatial relationships of nerves, blood vessels and othervital structures.Learningthesespatial skills requires a lengthy training period and much practicethat usually takes placein the operatingroom while under thesupervision of a senior surgeon atgreat financial cost and potential risk ...

Rapid diagnosis in conflict areas is a growingmilitary need, as troops areexposed to chemical threats (http://www.army.mil/e2/c/downloads/351235.pdf). Testingfor biomarkers in saliva has recently shown great promisein diagnostics, prognostics, and treatmentefficacy follow-up. In addition to itsconveniencefor field sampling and rapid testing,saliva is a rich body fluid with a number of physiologica ...

To address the DoDs Chemical and Biological Defense (CBD) program need for the development of real-time analytical technology for multicomponent vapor identification and quantification, Physical Optics Corporation (POC) proposes to develop a new Photoacoustic Gasses Optical Detector and Analyzer (PAGODA). It is based on a new system design that utilizes a novel, POC-developed photoacoustic transdu ...

We propose a high performance, cost-effective, universal Digital Assay Solutions platform with Mobile Readers, Assay Development and Calibration Software, and HIPAA-compliant cloud services for global health and defense applications. In Phase II project, we have developed the first generation product family receiving considerable interest from the assay manufacturers, government organizations and ...

Combat soldiers are exposed to vast numbers of dangerous chemicals with potentially adverse health outcomes. This SBIR proposal aims to develop a new class of saliva based diagnostic assays that will measure the bodys response to toxic chemical exposure with a panel of clinically validated biomarkers that are indicative of organ injury. The tests will leverage the proven functionality of lateral ...