List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. StrikeVEMP: Automated Portable Bone-Conducted Force Stimuli for Recording Acceleration-Produced coVEMPs

    SBC: Ear And Skull Base Center, Inc.            Topic: NIDCD

    DESCRIPTION provided by applicant Each year million Americans go to health care providers because of vertigo dizziness or balance problems It is the second most common complaint heard in doctorandapos s offices and will occur in of the nationandapos s population at sometime in their lives From through of US adults aged years and older million Americans had ve ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Preclinical and neuroimmunologic study of RTL1000 for methamphetamine addiction

    SBC: Virogenomics BioDevelopment Inc            Topic: R41

    DESCRIPTION provided by applicant Methamphetamine MA dependence is associated with long term damage to regions of the brain that control cognitive and psychiatric function One third to one half of MA dependent adults experience persistent cognitive and other psychiatric disorders up to three years or longer into remission The neuropsychiatric impairments that persist following abstinence ar ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. A screening assay for chemicals that affect the differentiation of human neural cells.

    SBC: Nzumbe, Inc.            Topic: NIEHS

    DESCRIPTION provided by applicant Human brain development represents a highly vulnerable time to chemical exposures because immature cells are actively undergoing differentiation into more complex cell types e g neurons astrocytes oligodendroglia to form neural circuits A major reason for this vulnerability is that neuronal differentiation requires critical time dependent changes to the ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Identifying activators of interferon regulatory factors for neuroprotection

    SBC: Neuralexo, LLC            Topic: NINDS

    DESCRIPTION provided by applicant Stroke is a leading cause of morbidity and mortality in the United States However less than of patients are eligible for the current approved interventions of tissue plasminogen activator or thrombectomy We seek to develop new therapeutics to reduce the extent of damage and functional impairment resulting from ischemic injury to the brain an area of signi ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. A Single Cell Multi-Protein Device to Facilitate Cancer Immunotherapy

    SBC: IsoPlexis            Topic: 102

    DESCRIPTION provided by applicant The most promising immunotherapies against cancer rely upon modulating CD and various CD T cells to activate against cancers like melanoma lymphoma and leukemia However the ability for researchers to measure the secreted effector proteins per heterogeneous T cell which determine the cellular potency against the cancer is limited today This Phase ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. In-home monitoring system for assessing gait using wall-mounted RF transceivers

    SBC: EMBEDRF LLC            Topic: NIA

    DESCRIPTION provided by applicant The goal of this project is to develop and evaluate a new system called GaitRF that can measure walking speed and other detailed gait parameters passively within the home The ability to move is a critical function that underlies the quality of life for elders as well as those suffering from neurologic or physical ailments Changes in aspects of gait such as wa ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Improved Protein Separations with Superficially Porous Particles

    SBC: ADVANCED MATERIALS TECHNOLOGY, INC.            Topic: 100

    DESCRIPTION provided by applicant Life sciences research and other critical bioanalytical applications would strongly benefit from faster and higher resolution liquid chromatographic HPLC separations of larger molecules including proteins peptides glycopeptides and glycans Many HPLC separations of biomedical interest such as resolution of protein mixtures require an hour or more and ma ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. High throughput laboratory X-ray illumination system for protein crystallography and screening

    SBC: Sigray, Inc.            Topic: 100

    DESCRIPTION provided by applicant High throughput laboratory x ray illumination system for protein crystallography and screening X ray protein crystallography is the single most effective method to determine macromolecule structures such as proteins The understanding of the three dimensional structure of proteins gives key insight into their functionality and provides essential information ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Mobile Internet-based Application to Promote Positive Parenting: Parent-Net

    SBC: EFFECTIVE HUMAN SERVICES LLC            Topic: NICHD

    DESCRIPTION provided by applicant There is a strong body of evidence supporting the use of behavioral parenting strategies in dealing with child behavioral problems Empirically supported behavioral parent training protocols exist e g Barkley Eyberg Forgatch and Patterson Kazdin WebsterMStratton and Reid to teach parents how to employ these strategies but th ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Targeted Pharmacological Chaperones for Neurological Diseases

    SBC: MARKER GENE TECHNOLOGIES INC            Topic: 106

    DESCRIPTION provided by applicant This Small Business Innovation Research Phase I project aims to develop new targeted pharmacological chaperones capable of modulating enzyme degradation in the Golgi apparatus and Endoplasmic Reticulum ER of living cells and tissues If successful the proposed research will provide breakthroughs needed to advance the discovery of promising new therapies and ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government