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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Microelectrode Dielectric Removal Via UV Laser

    SBC: Pi Medical Corp.            Topic: N/A

    The objective of our research is to demonstrate the application of ultraviolet (UV) laser ablationtechnology as an improved alternate to either local heating, ac arcing or plasma etching in the selectiveremoval of Parylene from neurophysiological microelectrodes. Phase I will perfect, quantify anddemonstrate the technique necessary for selective paralene removal from microelectrodes, as well asits ...

    SBIR Phase II 1995 Department of Health and Human Services
  2. Investigator Ready, Interconnected Microprobe Systems

    SBC: Pi Medical Corp.            Topic: N/A

    We will develop completed, implantable systems utilizing microelectrode probes, lead wires and percconnectors to record neural activity inside the body. High failure rates of current microprobe systill-suited interconnect systems and inadequate termination, cleaning and encapsulating processes anddevelopment effort would capitalize on existing photolithographically micromachined silicon microelec ...

    SBIR Phase I 1995 Department of Health and Human Services
  3. Novel Beetle Luciferases for Biomedical Development

    SBC: PROMEGA CORP.            Topic: N/A

    Though radioactivity is widely used in bioassays due to its high sensitivity and convenience, safety and environmental concerns have accelerated efforts to eliminate its use. Recent procedures using luminescence have often surpassed conventional isotopic methods; among these the luminescence of firefly luciferase is the most efficient. Relevant biomedical applications include reporter gene technol ...

    SBIR Phase II 1995 Department of Health and Human Services
  4. Developing Technologies for Studying Protein Prenylation

    SBC: PROMEGA CORP.            Topic: N/A

    Prenylation (the modification of proteins with the cholesterol biosynthesis intermediates C(15) fargeranylgeranyl) is a newly discovered postranslational modification that targets certain proteins tointerior of the cell, thereby regulating their biological activity. The best studied example illustrmodification is the farnesylation of p21ras, the protein encoded for by the ras oncogene which is imn ...

    SBIR Phase I 1995 Department of Health and Human Services
  5. Squeegee Design Effect on Carpal Tunnel Pressure

    SBC: SQUEEGEE PLUS!            Topic: N/A

    Repetitive use of hand tools, in particular those that compress the palm of the hand and are held wprecision grip may be a large part of the high incidence of carpal tunnel syndrome (CTS) that is ovework place. This proposal is to conduct preliminary investigations into the relationship of carpal tthe design of handles used on squeegees and related hand tools such as pliers and screwdrivers. Thein ...

    SBIR Phase I 1995 Department of Health and Human Services
  6. SQUEEGEE DESIGN EFFECT ON CARPAL TUNNEL PRESSURE

    SBC: SQUEEGEE PLUS!            Topic: N/A

    N/A

    SBIR Phase I 1995 Department of Health and Human Services
  7. Alcoholism Prevention Using Student Improvement Teams

    SBC: TANGLEWOOD RESEARCH INC            Topic: N/A

    We will develop, test, and disseminate a high school alcohol abuse prevention program. The programstudents identified as peer opinion leaders as members of a Student Improvement Team. Team members wand trained to complete three tasks. First, they will actively identify and comment fellow studentsacts. Second, they will serve as peer mediators. In this role they will actively intervene in situatcon ...

    SBIR Phase I 1995 Department of Health and Human Services
  8. Improving Drug Education--Concept Training for Teachers

    SBC: TANGLEWOOD RESEARCH INC            Topic: N/A

    N/A

    SBIR Phase I 1995 Department of Health and Human Services
  9. Vitamin D Based Anticancer Prodrugs

    SBC: Tetrionics, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1995 Department of Health and Human Services
  10. Screens for Identifying HIV Fusion Inhibitors

    SBC: Trimeris, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1995 Department of Health and Human Services

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