Award Data

DESCRIPTION (provided by applicant): Pulsus paradoxus (PP) is a valuable pathological vital sign in the management of asthma and in the rapid evaluation of patients with dyspnea in general. Early asthma management guidelines published by NHLBI in 1991 included a recommendation for physicians to measure PP in acutely asthmatic patients. Recent evidence continues to show that PP can play a role a ...

DESCRIPTION (provided by applicant): This Phase II project will complete the development of Icon Teacher, a product intended for certain children who require augmentative/alternative communication (AAC) intervention. In AAC systems, children who have not learned to speak may indicate wants and needs by responding nonverbally to symbols that represent desired items or activities (sometimes called ...

DESCRIPTION (provided by applicant): Over the last two decades, craniofacial anthropometry has found increasing application in clinical genetics and oral maxillofacial and reconstructive plastic surgery. Quantitative measurements have rendered the diagnosis of dysmorphic features both objective and reliable, a boon to geneticists and surgeons alike. Also, surgical planning has benefited from these ...

DESCRIPTION (provided by applicant): The long-term objective of this project is to develop a six-module computer-based course to educate parents of young children with Autism Spectrum Disorder (ASD) in the nature, purpose and procedures of behavioral intervention (BI). BI is a consensus "best practice" scientific methodology for teaching critical developmental skills and preventing/treating malada ...

DESCRIPTION (provided by applicant): Federal and state laws require that young children with disabilities or who are at risk for developing disabilities be provided with Early Intervention services according to their developmental needs. But currently, there is a critical shortage of skilled EI providers. The primary reason for this shortage is a lack of educational and training programs. Except ...

DESCRIPTION (provided by applicant): Technology developments aimed at extending the ability of the elderly to live independently often target those people with a disability, chronic condition, or other known reason requiring help with their care. A critical gap in current research, specifically addressed by this STTR program, is assistance technology for the population of persons over 65 years of ...

DESCRIPTION (provided by applicant): Sickle Cell Disease (SCD) is an abnormality of red blood cells (RBC) that affects approximately 72,000 people in the United States, or approximately 1 in every 500 African-Americans. With current therapies, the mortality in the United States is 50 percent by age 40. SCD is a chronic, debilitating disease associated with frequent painful crises, acute chest synd ...

The Phase I research conducted jointly by Research Support Instruments (RSI) and the Applied Physics Group of Princeton University has yielded results that could lead to a paradigm shift in combustion research being conducted on engines for both supersonic and hypersonic flight. Research to date has yielded laminar flame speed increases of 65%, and the physical models developed indicate that it ma ...

DESCRIPTION (provided by applicant): Cancer is a devastating group of diseases, among the most common causes of death for Americans. Current therapies for advanced disease are highly toxic and all too often ineffective. Our group has recently demonstrated a powerful innate inducible ability of human cells to recognize and respond to damaged DNA, a characteristic of cancer cells. Moreover, we hav ...

DESCRIPTION (provided by applicant): This project will develop visiBabble, sound recognition software to provide real-time contingent visual reinforcement of vocalizations produced by infants or preschool children. This program is intended for children who are delayed in the frequency and variety of pre-speech vocalizations they produce and, hence, are at risk for being non-speaking. The visiBabbl ...