Award Data

Endo-atmospheric flight at hypersonic speeds creates an extraordinarily harsh aerothermal environment which may lead to the formation of an ionized plasma layer around some parts of the vehicle. Free electrons in this plasma layer are formed via a combination of collisional ionization and oxidative reactions with carbon products and contaminants. From the perspective of electromagnetic interaction ...

SiO2 Materials Science (SiO2) is a U.S. advanced medical technology company that produces high-performance, durable, glass-equivalent primary containers that are uniquely designed to store, transport, and protect drugs, including those that require cold-chain storage. SiO2 is an SBA Defense SBIR/STTR Innovation Portal (DSIP) small business. SiO2’s primary containers are wholly manufactured in ...

Biowarfare agents pose a significant threat to military personnel and operations. Effective decontamination strategies that eliminate the biowarfare agents prior to human exposure can help mitigate risks associated with exposure. Traditional decontamination techniques rely on “wet” solutions such as chemicals including bleach. However, these decontaminants are unsuitable for sensitive equipmen ...

In order to address DoD’s urgent need for decentralized generation of hydrogen peroxide for decontamination on remote sites, ChromoLogic LLC (CL) proposes to develop an aerophilic-electrode-based membrane free electrolyzer (AMeFE) as a light-weight, energy saving, and high efficiency H2O2 generator to support application of SEDS. Electrolyte applied in AMeFE will maintain an optimal solution ...

Intelligent Optical Systems, Inc., in collaboration with Bowling Green State University, proposes to develop a field-rugged, eye-readable indicating spray solution that can immediately detect synthetic opioids over a large area of contamination (i.e., military vehicles, individual protective equipment, clandestine labs, etc.). The proposed chemosensor in a spray solution format will detect multipl ...

In its effort to provide necessary intelligence and analysis, the National Geospatial-Intelligence Agency (NGA) utilizes extensive traffic camera systems. However, the large amount of data overwhelms both analysts and existing processing methods. In order to provide a better understanding and reduce the search space for common problems such as target tracking, it is necessary to extract the camera ...

Infections of the central nervous system (CNS) are associated with brain swelling and increased cerebral blood volume, as well as focal cerebral perfusion deficits, variable levels of cerebral blood flow and cerebral vasculitis. The net result is increased intracranial pressure (ICP) along with significant risk of brain tissue herniation and ischemic syndromes. ICP monitoring is critical in the ma ...

Measurement of intracranial pressure (ICP) is essential in the diagnosis and management of numerous life threatening conditions. All current methods used clinically to measure ICP are invasive and require direct access to the cerebrospinal fluid giving them a significant side effect profile. The ability to measure ICP non-invasively would be a major milestone for patients. Spontaneous venous pulsa ...

The threat of organophosphate (OP) chemical warfare agents (CWA) to United States military personnel is a persistent problem due to the relative ease of manufacturing chemical threats compared to nuclear and biological agents. Human butyrylcholinesterase (BChE) has been identified as a probable bio-scavenger of OP CWAs that could be used to protect individuals that could be exposed to OP CWAs. The ...

Organophosphorus (OP) toxins and chemical warfare agents (CWA) are active nerve agents posing significant hazard for both soldiers and civilians. Butyrylcholinesterase (BChE) is a safe and effective bioscavenger that detoxifies OP and CWAs when injected either prophylactically or post-exposure; but a major technical problem has been producing a recombinant form of BChE with acceptable properties f ...