Award Data

BaySpec Inc., in collaboration with Pacific Northwest National Laboratory, proposes to develop a new portable multi-order mass spectrometry system that can sequence peptides derived from biological agents including bacteria, viruses, and toxins. During Phase I stage, a fully functional prototype instrument, based on an innovative design concept, was successfully built and the performance evaluatio ...

Filamentation of ultra-short laser pulse propagation in non-linear media offers significant potentials allowing to address numerous problems in military and commercial sectors. However, practical implementation of this requires an ability to control the USLP at its propagation through inhomogeneous media, like turbulent atmosphere. On the basis of our approach for combating turbulence effects on p ...

Areté proposes the development of Q-switched semiconductor lasers that can be scaled to produce high output peak powers within the blue/green wavelength band. The proposed system will utilize nanostructure quantum wavefunction engineering for gain material designs having extended excited state lifetimes and suppressed non-radiative processes to enable energy storage for high-peak-power optical pu ...

For effective protection against radiated threats, it is important to understand not only the physics of the threats, but also to quantify the effects they have on mission-critical electrical systems. Radiated vulnerability and susceptibility testing requires delivery of high peak power and peak electric fields to distant targets. The most practical solution to simulate such environments on large ...

CL-20 is the most powerful conventional explosive known, but its high cost has limited its adoption in a range of potential applications. Par of the challenge in making these materials is the complexity of the reaction used to prepare the polycyclic cage. The complexity of this reaction makes it difficult to have insight into the reaction and to improve it. Additionally, several of the intermediat ...

A Battlefield Airman (BA) has one of the most challenging positions in the military. BA personnel are tasked with the dual roles of being warfighters as well as Combat Controllers, Pararescuemen, Tactical Air Control Party (TACP) members and Special Operations Weather Technicians often while behind enemy lines. These complex duties require high fidelity training. In some cases, such as Pararescuem ...

Structural Health Monitoring (SHM) can be reliably used to perform on-line health monitoring of any type of structures with minimal human involvement. Current SHM systems can perform the functions required but are heavy, bulky and difficult to integrate with the structure to provide on-board real-time structural integrity assessment. Embedding of currently available sensors and electronics used by ...

Current scene projection hardware is challenged to simultaneously meet the requirements for high peak temperature (> 2000K), high resolution (2Kx2K), response time < 4 ms, cryogenic and temporally uniform photon flux. MEMS, Resistor arrays, liquid crystals, and photonic crystals all suffer in one or more areas. MEMS suffer from flicker and low dynamic range. Resistor arrays suffer from low frame r ...

Through this STTR contract, we propose to evaluate the efficacy of our vaccine, FlowVax Marburg, in nonhuman primates (NHPs). This will be achieved through four Tasks. In Task 1, we will manufacture the vaccine in a quantity sufficient for the animal studies. In Task 2, we will perform MHC genotyping on a representative population of NHPs and, based on results, select a set of MHC-matched NHPs for ...

There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terrible morbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditional vaccines have contributed greatly to public health, they have some limitations especially in the context of operati ...