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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. SUMO Fusions to Enhance Expression of Membrane Proteins

    SBC: LIFESENSORS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Rather modest success has yet been achieved in expressing and purifying membrane proteins as a prerequisite to obtain high resolution structures. Only 124 unique structures for membrane proteins have been resolved out o f gt 30,000 soluble proteins. This bottleneck can be divided into at least three major parts: i) the difficulty to express quantitatively and ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  2. Intravesical Liposome Treatment for Interstitial Cystitis

    SBC: Lipella Pharmaceuticals Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Interstitial cystitis (IC) is a chronic, severely debilitating disease of the urinary bladder. It can be described as a chronic inflammatory condition of the bladder wall, characterized by urinary frequency and urgency, and severe suprapubic and/or pelvic pain. Presently, there is limited medical therapy for IC and new and effective treatment is a major unmet ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  3. IDENTIFICATION OF BACTERIA DIRECT FROM BLOOD CULTURE

    SBC: MIDI, INC.            Topic: N/A

    DESCRIPTION (Verbatim from Applicant's Abstract):Rapid identification of bacteria direct from a blood culture bottle would speed up patient treatment and recovery, thereby also greatly reducing hospital care costs. The current procedure of subculturing typically takes from 24 to 48 hours to obtain bacterial identifications. Gas chromatographic analysis of b ...

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a cost-effective pmMRI for in vivo structural examination of bone

    SBC: MICROMRI, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): MicroMRI, Inc. Development of a cost-effective pfMRI for in vivo structural examination of bone Abstract Osteoporosis is a systemic bone disease characterized by low bone mass and abnormal bone quality. The current "gold standard", dual-energy x-ray absorptiometry (DXA), cannot assess bone quality and fails to detect > 50% of persons at greatest risk of fractur ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  5. DEFINITION AND DETECTION OF CLINICAL EEG FEATURES

    SBC: MOBERG RESEARCH INC            Topic: N/A

    N/A

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  6. NEWBORN SCREENING BY MULTIPLEX MOLECULAR ANALYSIS

    SBC: NEO GEN SCREENING, INC.            Topic: N/A

    DESCRIPTION: (Scanned from the Applicant's Description): A primary newborn screening protocol based on multiplex PCR and analysis of PCR products by low-density oligonucleotide arrays is being developed. The assay is based on DNA obtained from the universally collected neonatal blood card. The following disorders are detected through analysis of their common muta ...

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  7. Newborn Screening for Hearing Impairment

    SBC: NEO GEN SCREENING, INC.            Topic: N/A

    DESCRIPTION: (Adapted from applicant's abstract): The feasibility of screening borns for hearing impairmflent in an assay paralleling routine metabolic screening will be demonstrated. Hearing loss owing to heredity factors and cytomegalovirus are analyzed. DNA from the universally collected newborn filter paper blood card serves as the source of nucleic acids to pe ...

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  8. Community Ability Scale for Mental Health Clients

    SBC: NETWORK BEHAVIORAL HEALTHCARE            Topic: N/A

    N/A

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  9. DIRECT CEREBRAL OXYGENATION FOR ISCHEMIC STROKE

    SBC: NEURON THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION(adapted from applicant's abstract): Neuron Therapeutics, Inc. (Nfl) is developing a perfluorocarbon-containing artificial cerebrospinal fluid (Revoxyn) that can deliver oxygen and other nutrients directly to brain tissue even when vessels are occluded and cerebral blood flow compromised by ischemic stroke, a "brain attack." Preclinical studies demonstrated t ...

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  10. Low Antigenicity Factor VIII

    SBC: Octagen Corporation            Topic: N/A

    N/A

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
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