Award Data

DESCRIPTION (provided by applicant): The ultimate goal of this project is treatment of beta-thalassemia, a genetic blood disease, with antisense oligonucleotides. The project is based on the technology developed by the PI in which antisense oligonucleotides are used to restore correct functioning of a defective gene rather than, as commonly practiced, to inhibit the expression of an undesirable ge ...

DESCRIPTION (provided by applicant): The ultimate goal of this project is treatment of beta-thalassemia, a genetic blood disease, with antisense oligonucleotides. The project is based on the technology developed by the PI in which antisense oligonucleotides are used to restore correct functioning of a defective gene rather than, as commonly practiced, to inhibit the expression of an undesirable ge ...

THE PROPOSED RESEARCH WILL EXAMINE THE ANTI-SIMULATION TACTIC BOTH FROM THE STANDPOINT OF THE OFFENSE AND FROM THAT OF THE DEFENSE. THE OFFENSE POINT OF VIEW INCLUDES DETERMINING THE SIGNATURE FEATURES THAT THE ANTI-SIMULATION TACTIC ATTEMPTS TO DISGUISE AND THE DEGREE TO WHICH THESE FEATURES CAN BE MODIFIED BY PRACTICAL ALTERATIONS OF BOTH THE RV AND THE DECOY. THIS PORTION OF THE RESEARCH WILL A ...

It has been well established that disease in stored potatoes and many other vegetables and fruits generate a variety of volatile compounds that are released into the storage space Furthermore, specific types of disease produce volatile compounds that generate unique fingerprints on ultra-sensitive spectrographic molecular detection devices. The background atmosphere of commercial storage facilitie ...

Accurate estimations of the height and velocity of precision airdrop systems are required to control final deceleration maneuvers. Airdrop systems have a limited deceleration window, so robust and reliable estimations are required. Radar, sodar, and lidar sensors have been evaluated for this role with varying degrees of success. Foliage and vegetation prove troubling for many of the sensors. H ...

We investigate the development of a secure fuselet runtime environment built on a foundation of aspect-oriented web services. Aspect-oriented techniques enable the modularization of crosscutting concerns such as remote access, security, and monitoring using code instrumentation. We compose aspect-oriented instrumentation with web service technologies in a noninvasive and orthogonal manner, and lev ...

We investigate the development of a secure fuselet runtime environment built on a foundation of aspect-oriented web services. Aspect-oriented techniques enable the modularization of crosscutting concerns such as remote access, security, and monitoring using code instrumentation. We compose aspect-oriented instrumentation with web service technologies in a noninvasive and orthogonal manner, and lev ...

Solid State Scientific Corporation proposes to develop and demonstrate a unique sensor capable of providing detection and real-time classification of energetic point-target events. The novel dual-band spectral-temporal sensor addresses the specific need to identify rocket-propelled and explosive projectile threats from airborne platforms, as well as provide situational awareness capabilities by c ...

DESCRIPTION (provided by applicant): In Phase I of this work, Vortant Technologies created a new point-and-click (VPAC) device for non-invasive computer input. The new device tracks the position and orientation of the user's head, but requires no atta

Computational fluid dynamics (CFD) is used as an analysis tool to help the designer gain greater understanding of the fluid flow phenomena involved in the components being designed. The next step in the design process is to modify the design to improve the components performance, typically performed manually by the designer in a trial and error fashion. The innovations proposed herein will provide ...