List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. High Resolution Scanning Magnetometry

    SBC: MOMENT TECHNOLOGIES, LLC            Topic: NIBIB

    DESCRIPTION (provided by applicant): In Phase I we propose to test the feasibility of developing a high-resolution scanning magnetometry for neuroscience based on a simple, but novel concept of primary source mirror (PRISM). The PRISM can be made with different designs, but in this project it will be an air-filled glass pipette with a small glass plate at the end with a tilt of 45o toward bottom. ...

    SBIR Phase I 2011 Department of Health and Human Services
  2. Robotic System for Minimally Invasive Neurosurgical Endoscopic Procedures

    SBC: Etiometry Inc.            Topic: NIBIB

    DESCRIPTION (provided by applicant): Sterling Point Research, in conjunction with Children's Hospital Boston, intends to develop a multi-stage robotic endoscope for neurosurgical applications. This novel robotic system will utilize recently developed concentric tube technology to give neurosurgeons the ability to overcome the limitations of manually controlled flexible endoscopes. The cur ...

    SBIR Phase I 2011 Department of Health and Human Services
  3. Enhanced endophyte:poplar system for remediation of organic contaminants

    SBC: Edenspace Systems Corporation            Topic: NIEHS

    DESCRIPTION (provided by applicant): Trichloroethylene (TCE), one of the most common groundwater pollutants, is a known hepatotoxin and carcinogen. It has been widely used by industry and the military as a degreaser for metal parts: according to the Agencyfor Toxic Substances and Disease Registry, more than eight hundred Superfund sites in the United States are contaminated with TCE. Poplar, which ...

    SBIR Phase I 2011 Department of Health and Human Services
  4. Develop and Test an Online Biohazard Simulator to Train Skilled Support Personnel

    SBC: GRYPHON SCIENTIFIC, LLC            Topic: NIEHS

    DESCRIPTION (provided by applicant): The World Trade Center clean-up focused national attention on the inadequate training for skilled support personnel , OSHA's term for workers in trades (including construction, demolition and transportation) deployed to support disaster response (Lippy and Murray, 2003). While the relevant OSHA standard (29CFR 1910.120) provides detailed training for emer ...

    SBIR Phase I 2011 Department of Health and Human Services
  5. Field Deployable Vapor Intrusion Monitor

    SBC: Lynntech Inc.            Topic: NIEHS

    DESCRIPTION (provided by applicant): Vapor intrusion is the migration of volatile chemicals from the subsurface into overlying buildings, one of the major causes for a large population exposure to hazardous chemicals. These volatile chemicals are often theresult of buried waste and/or contaminated groundwater that can emit vapors that may migrate through subsurface soils and into indoor air spaces ...

    SBIR Phase I 2011 Department of Health and Human Services
  6. Optoacoustic system for monitoring biodistribution of nanoparticles in vivo.

    SBC: TOMOWAVE LABORATORIES, INC.            Topic: NIEHS

    DESCRIPTION (provided by applicant): We propose novel application of optoacoustic tomography for non-invasive and quantitative analysis of nanoparticle biodistribution in preclinical research. Novel nanotechnology-based treatments of cancer and other diseases with increased specificity and enhanced therapeutic potential are being actively developed at present. There is a pressing need for low-cost ...

    SBIR Phase I 2011 Department of Health and Human Services
  7. Prevention of Retinopathy of Prematurity with a Novel Bifunctional Redox Reagent

    SBC: RADIKAL THERAPEUTICS, INC.            Topic: NEI

    DESCRIPTION (provided by applicant): Retinopathy of prematurity (ROP) is present in up to 70-85% of very low birthweight premature infants (lt 1 kg). The more severe forms of ROP (Grades 3-5) account for more than 50% of injuries and are associated with lifelong visual impairment, including blindness. There are no pharmaceutical agents, or other measures, approved for the prevention of ROP. A ...

    SBIR Phase I 2011 Department of Health and Human Services
  8. Vision-QOL-CAT: A Functional Health CAT for those with Visual Disorders

    SBC: John Ware Research Group, Inc.            Topic: NEI

    DESCRIPTION (provided by applicant): With the aging of the population, vision loss is a growing public health problem affecting more than 3 million Americans. The impact of eye disease on health-related quality of life (HRQOL) and the benefits of new treatments are not well understood and have not been compared with those for other medical conditions. Although self-assessment tools for measuring t ...

    SBIR Phase I 2011 Department of Health and Human Services
  9. Advanced Laser Source for High-speed Adaptive Optics OCT

    SBC: Physical Sciences Inc.            Topic: NEI

    DESCRIPTION (provided by applicant): Physical Sciences Inc. (PSI) proposes to develop a new adaptive optics imaging approach to high- speed 3D-retinal mapping with enhanced Fourier Domain Mode-locked (FDML) swept-source technology. PSI is currently engaged in ongoing development of high performance, high resolution multimodal adaptive optics (AO) retinal imagers. Such systems resolve and quant ...

    SBIR Phase I 2011 Department of Health and Human Services
  10. Long-Acting Mucus-Penetrating Steroid Particles for Treatment of Eye Inflammation

    SBC: KALA PHARMACEUTICALS, INC.            Topic: NEI

    DESCRIPTION (provided by applicant): Inadequate treatment of ocular inflammation causes severe discomfort and complications, including blindness. Current means of treating ocular inflammation cannot sustain long-term efficacy without compromising patient safety, comfort or compliance. Conventional eye drops, which are preferred over other ophthalmic and systemic dosage forms due to patient comfort ...

    SBIR Phase I 2011 Department of Health and Human Services

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government