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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 41 - 50 of 23867 results
  1. Managing Vascular Dementia Risk Factors with SymTrend

    SBC: SymTrend inc            Topic: NIA

    Project Summary AbstractAbstractDiseases of blood vessels in the brain culminate in vascular dementiaVaDand ultimately rob one of independence in activities of daily living in elder yearsThey often commence an insidious progression in early to midlife with a concomitant diminution in work proficiencyVascular dementia is treatablehoweverSuccessful containment of the progression requires rigorous ma ...

    SBIR Phase I 2018 Department of Health and Human Services
  2. Rapid, Simple and Cost-Effective Detection of Human Cell Line Contamination

    SBC: Nuprobe Usa, Inc.            Topic: R

    Summary Cell line contamination and misidentification have dramatic repercussions in the field biomedical researchlargely contributing to the growing concerns about irreproducible results and posing a significant burden on the global biomedical research budgetWhile the general awareness about these issues has raised over the last yearscurrent authentication technologies such as short tandem repeat ...

    SBIR Phase I 2018 Department of Health and Human Services
  3. Web-based App to Alleviate Loneliness and Isolation in Older Adults at Home

    SBC: VIGOROUS MIND INC            Topic: NIA

    ABSTRACT Loneliness contributes to physical and psychological chronic illnessesfunctional decline and mortality in older adultsThe fast growing older population coupled with the worsening shortage of caregivers will soon present our nation with severe societal and economic challengesOlder adults often struggle to maintain quality of life and independence in the presence of chronic diseases and iso ...

    SBIR Phase I 2018 Department of Health and Human Services
  4. Astrocyte activation by small-molecule ADORA3 agonists: a novel therapy for Alzheimer's disease

    SBC: ASTROCYTE PHARMACEUTICALS INC.            Topic: NIA

    PROJECT SUMMARY Alzheimerandapos s diseaseADis an area of significant unmet need that creates a national burden of$billion annuallyAD is the leading cause of dementiaaffectingof Americans over the age ofDemographic shifts and the age related nature of AD will soon place this disease as the costliest health care expenditure in the U Swith a projected impact of $trillion per year byCurrent therapies ...

    STTR Phase I 2018 Department of Health and Human Services
  5. A practical platform for in-home remote monitoring of cognitive-frailty

    SBC: BioSensics LLC            Topic: NIA

    AbstractCognitive frailtythe combined presence of physical frailty and cognitive impairmentis a strong and independent predictor of cognitive declineThe International Association of Gerontology and Geriatrics and the International Academy on Nutrition and Aging have recommended the use of cognitive frailty assessment to track the progression of mild cognitive impairmentMCItowards dementiaAlzheimer ...

    STTR Phase I 2018 Department of Health and Human Services
  6. The Development of a High Throughput Whole Brain Alzheimer's Disease Drug Screening Pipeline

    SBC: Tissuevision Inc            Topic: NIA

    Project Summary Alzheimer s diseaseADis a debilitating neurodegenerative disease affecting roughlyinpeople over the age ofInthe total cost of AD in the United States was estimated at $billion and is predicted to climb to $trillion by the yearDespite enormous efforts invested in finding a cureit has proven extremely difficult to develop treatments for ADContributing factors behind this difficulty i ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD

    SBC: MASSACHUSETTS GENERAL HOSPITAL            Topic: NIA

    Abstract Overmillion Americans are currently affected by Alzheimerandapos s diseaseADwith an economic burden estimated at andgt$billion year inthat is projected increase at least four fold over next several decadesIn spite of the dearth of pharmacological options to modify the course of the disease at presentthe field has developed accurate biomarkers that demonstrate that the pathology of AD is p ...

    STTR Phase I 2018 Department of Health and Human Services
  8. A GIP Companion Drug for Enhancing Metabolic Benefits of Long-Acting GLP-1

    SBC: Velum Incorporated            Topic: NIA

    There is a world wide twin epidemic of obesity and TypeDiabetesT Dwith an urgent need to find effective new drug treatments for inducing weight lossStable derivatives of the endogenous glucoregulatory hormoneglucagon like peptideGLPare in clinical use for the treatment of T D but are of equally great interest as an emerging treatment of obesity and of age related neurodegenerative conditions inclu ...

    STTR Phase I 2018 Department of Health and Human Services
  9. Building a commercially scalable bionic pancreas for automated diabetes management

    SBC: Beta Bionics, Inc.            Topic: 200

    Through ayear collaboration between Boston UniversityBUand the Massachusetts General HospitalMGHwe have built insulin only and bihormonal con gurations of our bionic pancreasBPand extensively tested them in inpatientoutpatientand real world home use studies in people with typediabetesT DWe have also conducted preliminary clinical studies testing the insulin only con guration of our BP in people wi ...

    SBIR Phase I 2018 Department of Health and Human Services
  10. Effect of Surface Finish and Post-Processing on the Fatigue Life of Additively Manufacturing Parts

    SBC: Triton Systems, Inc.            Topic: N182126

    Triton will develop a surface finishing process that can efficiently post-process additively manufactured metallic components to a consistent finish while enhancing material properties and part performance. Naval materials of interest include titanium, aluminum, nickel, aluminum, bronze, and stainless steel alloys.

    SBIR Phase I 2019 Department of DefenseNavy

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