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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Antibody therapeutics- feasibility study on hormone-refrectory prostate cancer m

    SBC: ATTOGEN, INC            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to evaluate the therapeutic feasibility of a humanized antibody drug DAPI- 01 (anti-FGFR2-IIIc) in prostate cancer model systems. The molecular target of the antibody is fibroblast growth factor receptor-2 (F GFR2) isoform IIIc, which is involved in androgen-independent tumor growth and metastasis. Our specialized antibody drug is designed with the i ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  2. WEARABLE MULTICHANNEL VIBROTACTILE ARRAYS FOR THE DEAF

    SBC: AUDIOLOGICAL ENGINEERING CORPORATION            Topic: N/A

    THE LONG-TERM OBJECTIVE OF THIS STUDY IS TO MAKE AVAILABLE WEARABLE TACTILE AIDS WITH EIGHT OR MORE CHANNELS AND WITH SUITABLE PERFORMANCE, SIZE, AND CONVENIENCE CHARACTERISTICS TO MEET THE REQUIREMENTS OF THE MARKET. THE IMMEDIATE TASK IS TO ASSESS THE POTENTIAL OF A SPECIFIC TYPE OF VIBRATOR ELEMENT FOR USE IN AN INTEGRATED STIMULATOR ARRAY CONSISTINGOF EIGHT OR MORE VIBRATORS. ADDITIONALLY, A Z ...

    SBIR Phase II 1988 Department of Health and Human Services
  3. Lower-limb prosthetic alignment using force-line vector visualization

    SBC: BERTEC CORP            Topic: N/A

    DESCRIPTION (provided by applicant): This force-line vector visualization system will address prosthetists' and physicians' needs for a method of realtime displaying the ground reaction forces (GRF) generated during amputee ambulation coupled with images of that movement. This method provides an accurate visual representation of the magnitude, origin, and orientation of the GRF as it passes thro ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  4. Lateral flow assay for detecting colonization by Streptococcus agalactiae

    SBC: BIOHELIX CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Streptococcus agalactiae, a.k.a. group B streptococcus (GBS), is one of the leading causes of morbidity, and mortality among newborns. We propose to develop a molecular assay for GBS using our proprietary helicase depe ndent amplification (HDA), and a lateral flow strip embedded in a device that encloses the reaction vessel to prevent contamination of the labo ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  5. Development of a novel whole genome amplification method that mimics nature

    SBC: BIOHELIX CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): BioHelix is the exclusive licensee for a novel, primase-based Whole Genome Amplification (pWGA) technology invented by Drs. Stanley Tabor and Charles Richardson at Harvard Medical School. This pWGA system utilizes multi ple replication proteins including a primase/helicase, a DNA polymerase, a single-stranded DNA binding protein, and several other accessory pro ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  6. Herpes virus typing assay for detecting genital herpes

    SBC: BIOHELIX CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of our NIAID Biodefense Phase I SBIR program was to develop, and commercialize field deployable nucleic acid analysis devices for use in biodefense applications. We have begun to sell IsoAmp II kits that will allow our clients to develop home brew assays (we list customers in the commercialization plan). For example, the LANL has obtained NIH fu ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  7. Point of care genotyping assays, and algorithm for warfarin dosing

    SBC: BIOHELIX CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): On August 16, 2007, the FDA updated the label for warfarin to include information in the precautions section to remind physicians that people with variations in the CYP2C9 and VKORC1genes may require a lower initial d ose of the drug (see http://www.fda.gov/cder/drug/infopage/warfarin/default.htm). Unfortunately, the FDA did not provide specific guidance to p ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  8. Low cost molecular assay for HIV

    SBC: BIOHELIX CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to develop a rapid, low cost, threshold assay for the detection of HIV infection of HIV vaccination trial participants. Infection by HIV, and viral load are the usual end points for Phase III HIV vaccination trials. Ongoing Phase III HIV vaccine trials require a simple, and low cost molecular diagnostic test that can detect HIV infection in immuniz ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  9. Whole Mouse Cryo-Imaging

    SBC: BIOINVISION INC            Topic: N/A

    DESCRIPTION (provided by applicant): BioInVision, Inc. and Case Western Reserve University researchers will develop a cryo-imaging system for 3D imaging of mice. It will serve very many applications in biological research and the biotechnology industry, in cluding mouse anatomical phenotyping, drug delivery, imaging agents, metastastic cancer, pathogen/immune system response, and stem cells/regene ...

    STTR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  10. PURIFIED BOVINE HEMOGLOBIN FOR CARDIAC PRESERVATION

    SBC: BIOPURE CORPORATION            Topic: N/A

    BIOPURE CORPORATION HAS SUCCESSFULLY MANUFACTURED A POLYMERIZED BOVINE HEMOGLOBIN SOLUTION WHICH PHYSIOLOGICALLYOXYGENATES AS WELL AS OR BETTER THAN RED BLOOD CELLS. KEY PERFORMANCE CHARACTERISTICS INCLUDE BETTER 0(2)/CO(2) EXCHANGE AT THE CELLULAR LEVEL THAN FRESH HUMAN BLOOD. THE PRODUCT IS ESSENTIALLY FREE OF ENDOTOXINS, PHOSPHOLIPIDS, CLINICALLY ANTIGENIC AGENTS, PLASMA PROTEINS, LIPIDS OR OTH ...

    SBIR Phase I 1988 Department of Health and Human Services
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