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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Universal Influenza Vaccine

    SBC: VERSATOPE THERAPEUTICS, INC.            Topic: NIAID

    Abstract A universal influenza vaccine that is capable of protecting against all strains of influenza is a high priorityThe Centers for Disease Control andampPreventionCDCestimate the economic impact of seasonal influenza in the United States to range from $to $billion and pandemic influenza to range from $to $billionThe proposed research directly addresses the limitations of both pandemic and sea ...

    SBIR Phase I 2018 Department of Health and Human Services
  2. A wearable device to detect opioid overdose and to prevent death

    SBC: Bioresp Technologies, Inc.            Topic: NIDA

    Bioresp TechnologiesIncproposes development of RespiLifea new wearable device to to track physiologic data for early detection of opioid overdose and to relay data and the generated alerts to relevant caregivers for further interventionThe goal is to reduce the number opioids related deaths by early detection of overdoseOpioid epidemic death toll has quadrupled sinceAbout half of those deaths are ...

    SBIR Phase I 2018 Department of Health and Human Services
  3. UroLogic: Rapid, Near-to-Care Identification and Antimicrobial Susceptibility Testing of Microbes in Urine Specimens from Outpatients with Suspected Urinary Tract Infection

    SBC: MicrobeDx, Inc.            Topic: NIAID

    Antibiotic resistance is a global healthcare crisis that is forcing physicians to treat common infectious diseases with ever more potent antibioticsNew diagnostic strategies are urgently needed for rapid pathogen identification quantificationIDQand antimicrobial susceptibility testingASTto guide antibiotic selection for patients with urinary tract infectionUTIMicrobeDx will design and test UroLogi ...

    SBIR Phase I 2018 Department of Health and Human Services
  4. Real-time monitoring of inorganic chloramines near swimming pools

    SBC: SEACOAST SCIENCE, INC.            Topic: NCEZID

    Chlorination of swimming pools is necessary to insure swimmers healthhoweverthis process results in the formation of organic and inorganic chloraminesThe presence of volatile inorganic chloramines proximate to the water surface cause a variety of maladiesieirritation to the eyesskinand respiratory systemThe concentration of the chloramines tend to accumulate specifically in indoor poolsIn response ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. A Customizable Real-Time Biosensor for Continuous Monitoring of Water Contaminants

    SBC: Quantitative Biosciences, Inc.            Topic: NIEHS

    Ensuring access to clean water for generations to come will involve developing novel approaches to determining the safety and composition of potable water that are practical and affordableArsenicmercuryand cadmium are three of the top priorities among hazardous substances commonly found at Superfund sitesas they are linked to health problems in people exposed to them in drinking wateryet the curre ...

    SBIR Phase I 2018 Department of Health and Human Services
  6. Quorum:natural product discovery via mass spectrometry and molecular networking

    SBC: DIGITAL PROTEOMICS LLC            Topic: 400

    Project Summary Advances in genome miningand consequent realization of untapped microbial diversity has lead to renewed interest in natural productNPdiscoveryNPs are a rich source of therapeutic candidateswith a long history of successes in combating infectious diseasesand oncologyThe emergence of antibiotic resistant bacteria like Cdifficile and carbapenem resistant enterobacteiaceaeCREonly empha ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. Preclinical development of an intravaginal ring for the sustained release of Pritelivir for the treatment and prophylaxis of Genital Herpes in women

    SBC: AURITEC PHARMACEUTICALS, INC.            Topic: NIAID

    SUMMARY The broadlong term goal of this project is to develop a pritelivir intravaginal ringIVRfor the treatment and pre exposure prophylaxis of genital herpesa common problem that affects more thanmillion AmericansRecurrences are common and may be painfulInfection is life longPritelivir is a promisinghelicase inhibitor that proved superior to existing therapies in Phaseclinical trialsbut whose cl ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. Development of a Human Liver Microphysiological System For Alcoholic Liver Disease

    SBC: Emulate, Inc.            Topic: 500

    PROJECT SUMMARYAlcoholic liver diseaseALDincludes a broad range of progressive disease stagesfatty liveralcoholic steatohepatitisASHliver fibrosisliver cirrhosisand hepatocellular carcinomaIn spite of being one of the major causes of morbidity and mortality in the worldthere are currently no effective strategies that can preventtreat or monitor the progress of ALD owing primarily to lack of human ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. Cerberus therapy for metastatic disease

    SBC: Talapo Therapeutics            Topic: 102

    Metastasis is the most common cause of cancer related mortalityyet there are currently no therapeutic options that can be used to stop the spread of malignant cellsRecentlytwo members of the Transforming Growth Factorfamilythe secreted ligands Nodal and Bone Morphogenetic ProteinBMPhave been linked with increased metastasis in breast and other cancersThese cytokines activate stem cell programs in ...

    SBIR Phase I 2018 Department of Health and Human Services
  10. Multiplexed single-cell contractility assay to develop therapeutics for asthma and hypertension

    SBC: Forcyte Biotechnologies, Inc.            Topic: 100

    SUMMARYABSTRACT Asthmatic bronchoconstriction and hypertensive vasoconstriction are extremely common disease states in which excessive contractile cellular forces directly contribute to the pathophysiologyExisting treatments for these diseaseswhich affectmillion andmillion Americansrespectivelyhave severe side effectsbecome desensitized over prolonged useor lack efficacy altogetherIn particularLAB ...

    SBIR Phase I 2018 Department of Health and Human Services
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