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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Transrectal Ultrasound Ablation Of The Prostate

    SBC: ACOUSTIC MEDSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Prostate cancer continues to be a significant health problem, being the second most common cause of cancer-related death among American men. Local recurrence of prostate cancer is the most frequently detected failure of primary treatment, which propels subsequent treatment regimens onto an aggressive orbit, with the primary objective being to stop the tumor ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  2. Rapid Response Vaccines for Botulinum Neurotoxins

    SBC: Iterative Therapeutics Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Botulinum neurotoxins (BoNTs) are the most potent protein toxins known. Given their potent toxicity and their potential use in bio-warfare scenarios, BoNTs are included among the Category A select agents. The currentlyavailable pentavalent toxoid vaccine requires multiple boosters before being effective, and protects unequally against the different BoNT serotyp ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  3. Multifunctional Peptides for (MRI) Imaging

    SBC: CDG THERAPEUTICS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Our overall goal is to expand the role of CPPs in molecular imaging at the patient level using large animal models of human tumors and a peptide agent that inherently provides 1) preferential access to a wide variety ofhuman solid (and hematologic) tumor cells, 2) an increased intracellular concentration (2-12 fold) over histologically matched normal cells, and ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  4. Optimal Prevention and Control of Periodontal Disease: The Periodontal Pocket Irr

    SBC: C. PAXTON DESIGNS INC.            Topic: NIDCR

    DESCRIPTION (provided by applicant): Periodontal disease is a chronic bacterial infection that affects the gums and bone that surrounds supported teeth. According to the NIH fact sheet an estimated 80 percent of American adults have some form of periodontal disease. Gingivitis, a milder form of gum disease, is caused by plaque bio-film, which surrounds the teeth at the base of the gum line, causin ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  5. New drug Vida-5 for treating chronic kidney disease progression

    SBC: Vidasym, Inc            Topic: NIDDK

    DESCRIPTION (provided by applicant): Twenty-six million people in America have chronic kidney disease (CKD). Anemia, cardiovascular diseases, secondary hyperparathyroidism, renal osteodystrophy and other complications are common in CKD. Current treatmentsincluding ACE inhibitors for CKD patients mainly focus on managing symptoms and disease complications. Despite the various treatments available, ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  6. E-Learning Assisted HAZWOPER Training for Coroners and Medical Examiners

    SBC: D&E TECHNICAL, INC            Topic: NIEHS

    DESCRIPTION (provided by applicant): Human death investigations must by law be properly implemented even when the decedent is involved in or near to the scene of a hazardous materials emergency. This project intends to develop worker health and safety training for those staff of coroners and medical examiners who investigate deaths in hazardous materials environments. This innovative training will ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  7. Portable Instrument for Chemifluorescent Detection of Lead in Dust

    SBC: Strategic Government Business Consulting Group, Ltd            Topic: NIEHS

    DESCRIPTION (provided by applicant): Lead poisoning has been identified as the number one environmental health problem in the United States affecting children. The CDC estimates that 30 percent of in inner city children have high lead levels and that one million children have lead levels greater than 10 5g/dL of blood. Childhood exposure to low levels of lead have been shown to cause permanent neu ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  8. Testing Feasibility of SlipChip Workflow for Membrane Protein Crystallization

    SBC: TALIS BIOMEDICAL CORP            Topic: NIGMS

    DESCRIPTION (provided by applicant): Membrane proteins are crucial to a wide variety of physiological processes, functioning as chemical receptors, transport channels and signal transducers. It is estimated that over half of drug targets are membrane proteins. Structural knowledge of membrane proteins is of very high biomedical significance. Crystallization of membrane proteins is an important app ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  9. SlipChip for Target Enrichment for Next-Gen Sequencing by Multiplexed PCR

    SBC: TALIS BIOMEDICAL CORP            Topic: NHGRI

    DESCRIPTION (provided by applicant): 1. For the past 30 years, Sanger sequencing has enabled the determination of a sequence of nucleotide 2 bases on a small segment of DNA, with the crowning achievement of the technology being the complete 3 elucidationof the human genome at a cost of several hundreds of millions of dollars. Recently, next- 4 generation sequencing technologies have been deve ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  10. NIH SBIR Phase I: UNCD as Bio-Inert Interface for Anti-Thrombogenicity Applicati

    SBC: Advanced Diamond TechNologies, Inc.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Due to the gruesome toll of cardiovascular disease (CVD) through-out the world, improvements in treatment for CVD are of profound medical, societal and economic importance. The proposed research will be conducted in collaboration with renowned artificial heart pioneer, Dr. Robert Jarvik, and is designed to improve the operating lifetime of Ventricular Assist De ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
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