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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Strep-CaDI: A fast, accurate, and sensitive point-of-care test for Group A Streptococcus

    SBC: BURST DIAGNOSTICS INC            Topic: NIAID

    SUMMARY The current rapid antigen detection tests for group A strep lack sensitivity and result in upwards of 10 million unnecessary antibiotic treatments provided to children each year. Current diagnostic methods utilized when a patient presents at a clinic with a sore throat include a throat swab and rapid strep test. A positive rapid test results in antibiotic prescription, but due to the low s ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. A wearable high-density MEG system with uOPMs

    SBC: FieldLine Inc.            Topic: 101

    Abstract In this Phase II project, we will build a complete high-density wearable full-head MEG system using our micro-OPM sensors and to cross-validate our system against current SQUID-based MEG systems. A complete system consists of (1) the sensor system - an array of 128 sensors and their control electronics that performs synchronous data collection and control; (2) a MEG cap that conforms to t ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  3. Citizen-Science Technology for Healthy Living at Home

    SBC: Access Sensor Technologies LLC            Topic: 102

    Abstract Human exposure to air pollution is the leading environmental risk factor for premature morbidity and mortality worldwide and, in the United States (U.S.), people of color suffer from many diseases associated with exposure to air pollution at higher rates than white people. Our understanding of human exposure to air pollution is based largely on measurements of outdoor pollutant concentrat ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a novel product for skin decontamination after exposure to chemical warfare agents

    SBC: ARMIS BIOPHARMA, INC.            Topic: 105

    ABSTRACT With the increasing threat of terrorism, the development of countermeasures for the event of a chemical attack on civilians has become a high priority. Mass casualty events in which chemical warfare agents (CWA) would be employed in an attack on a civilian population, are a concrete risk. Because of significant differences between members of the military and civilians, existing countermea ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  5. Leveraging Label-Free Digital Imaging to Enable Rapid On-Site Evaluation (ROSE) During Thyroid Biopsy Procedures

    SBC: PATHWARE INC.            Topic: 102

    Project Summary/Abstract Pathware is developing Bioptic™, an imaging platform to analyze biopsy samples at the point-of-care. The system will rapidly digitize unstained biopsy samples and utilize computer-aided detection/diagnostics to enable quick and efficient evaluations by pathologists. Typical barriers to point-of-care diagnostics are overcome by combining novel computational microscopy wit ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. DT-EGF Toxic Fusion Protein for the Treatment of Bladder Cancer

    SBC: Aurora Oncology, Inc.            Topic: 399

    Project Summary/Abstract Bladder cancer causes over 165,000 annual deaths worldwide with 70,000 new cases and 16,000 deaths reported in the US. Treatment of superficial bladder cancer by resection and BCG administration is unsuccessful in 40% of cases with recurrences eventually requiring cystectomy or other aggressive therapy; new therapies are needed. The role of Epidermal Growth Factor Receptor ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  7. Caring4Caregivers: A theory-driven mobile solution to promote self-care and well-being among caregivers of individuals with Alzheimer’s andrelated dementias

    SBC: Pro-Change Behavior Systems, Inc.            Topic: R

    7. Project Summary/Abstract Over 11 million Americans are currently providing unpaid care to a family member or friend with Alzheimer's disease or a related dementia (ADRD). While caregiving can be a positive experience that brings meaning and an increased sense of purpose, it can also take a toll. Nearly 60% of ADRD caregivers rate their emotional distress as high or very high, and over 30% suffe ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  8. Feasibility and design of a novel smartphone app to deliver blood pressure-lowering inspiratory muscle strength training

    SBC: KLEIN BUENDEL, INC.            Topic: NHLBI

    PROJECT SUMMARYHigh blood pressure (BP), particularly high systolic BP (SBP), is the major modifiable risk factor for cardiovascular diseases (CVD) and related conditions. Indeed, over 50% of all adults have above-normal SBP (≥120 mmHg), placing them at increased disease risk. In addition, these adults face ~$2000/year in excess medical expenses compared to their peers with normal BP. Rates of B ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Flu Vaccine Production Using a Novel Pandemic Response and Prevention Manufacturing Method

    SBC: SOLARIS VACCINES, INC.            Topic: NIAID

    PROJECT SUMMARY/ABSTRACT The current global pandemic has highlighted the need to develop new methods for creating vaccines. Many approaches today face limitations with breadth and duration of protection; flexibility and adaptability for emerging strains; manufacturing speed and safety; and storage and distribution. SolaVAX™ inactivation technology offers an elegant solution for quickly generatin ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  10. Topical Drug Delivery System as an Anti-Inflammatory and Pro-Angiogenic Therapy for Diabetic Wound Healing

    SBC: GELSANA THERAPEUTICS INC            Topic: 200

    SUMMARY Impaired wound healing in diabetic patients represents a major clinical problem, resulting in prolonged hospitalizations and significant healthcare expenditures. The financial burden of this is extreme, representing $78 billion annually in the U.S. alone. Two-thirds of all non-traumatic amputations are preceded by a diabetic wound, and every 20 seconds a lower limb is lost to a diabetic wo ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
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