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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Inter-alpha Inhibitors in Hypoxic-Ischemic Brain Injury

    SBC: PROTHERA BIOLOGICS, INC.            Topic: 105

    Perinatal brain injury resulting in mental retardation and cerebral palsy is the most severe disability in children and affects 40-148 in preterm and 1–2/1000 in full term infants. This places a huge burden on society, emphasizing the critical need for improved prevention/treatment strategies to decrease perinatal brain injury. Hypothermia (HT) is the only FDA approved therapy to attenuate brain ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Using Structured Light Sensing with Machine Learning to Detect Unwitnessed In-Home Falls

    SBC: Applied Universal Dynamics, Corp.            Topic: NIA

    Project Summary/Abstract Older adults are disproportionately affected by falls. Older adults who have memory loss (mild to moderate cognitive impairment) can forget to wear wireless alert pendants or wristbands that are used in case they fall in their home. Falls among adults 65 and older caused over 34,000 deaths in 2019, making it the leading cause of injury death for that group. Older adult fal ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. A software tool to facilitate variable-level equivalency and harmonization in research data: Leveraging the NIH Common Data Elements Repository to link concepts and measures in an open format

    SBC: ALGENTA TECHNOLOGIES LLC            Topic: R

    Abstract The National Institute on Aging (NIA) supports numerous studies and archives that collect and disseminate critical data about the aging population of the United States. By supporting the collection and dissemination of longitudinal and multidisciplinary data, the NIA provides researchers the opportunity to measure change and stability in individuals over time, as well as to investigate ag ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Intuitive Child Safety Seat to Increase Security

    SBC: Minnesota HealthSolutions Corporation            Topic: NICHD

    Project Summary/Abstract Minnesota HealthSolutions Corporation (MHS) proposes to develop a child safety seat with a novel intuitive harness tensioning system to improve the rate of proper harnessing of children into child safety seats. Children are harnessed into child safety seats via a 5-point harness with shoulder straps that buckle at the crotch. The entire harness assembly must be properly te ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Cue-induced drug craving monitoring for opioid use disorder with visual evoked potentials

    SBC: NEUROTYPE INC.            Topic: NIDA

    Project Summary / Abstract More than 2 million people in the United States have an Opioid Use Disorder (OUD). Overall, at least half of the treatment-seeking population relapse, contributing to over 75,000 overdose deaths annually. The purpose of this SBIR Fast-Track application is to create a regulated device to objectively monitor Cue-Induced Craving (CIC) in Opioid Use Disorder (OUD) patients. ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Inter-alpha Inhibitors in Experimental Necrotizing Enterocolitis

    SBC: PROTHERA BIOLOGICS, INC.            Topic: NICHD

    Necrotizing enterocolitis (NEC) is a devastating acute inflammatory condition of the gastrointestinal tract resulting in intestinal necrosis, systemic sepsis and multi-system organ failure found mostly in infants born prematurely. Despite modern medical advances in the past decade, the etiology remains elusive and morbidity and mortality are still unacceptably high. It has been concluded that the ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Novel warming and massaging bra for improved breast milk expression

    SBC: Momease Solutions, Inc.            Topic: NICHD

    PROJECT SUMMARY Breast milk is an unmatched bioactive source of nutritional, immunological, and neurodevelopmental benefits for infants that evolves as an infant grows to meet their unique health and nutritional needs. As such, breast milk is considered the clinical gold standard for infant feeding, and both the American Academy of Pediatrics (AAP) and the World Health Organization (WHO) recommend ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Commercial Readiness for Direct-to-Digital Pathology

    SBC: APPLIKATE TECHNOLOGIES, INC.            Topic: NCI

    Abstract Project Summary Applikate Technologies has developed Clearing Histology with Multiphoton Microscopy (CHiMP), a novel tissue processing and imaging platform that provides direct-to-digital images from intact pathology tissue specimens, such as biopsies, without the need for wax embedding, slicing, or scanning of slides. The application of this technology to cancer diagnosis will reduce err ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a novel personalized medicine platform using apheretically isolated circulating tumor cells to assess drug responsiveness in prostate cancer

    SBC: ASTRIN BIOSCIENCES, INC.            Topic: 102

    Project Summary Metastatic prostate cancer is a notoriously heterogeneous disease that is difficult to treat. The five-year survival rate has not improved over the past twenty-five years and the median survival rate for those diagnosed with metastatic castration resistant prostate cancer (mCRPC) is only 15-36 months. Precision medicine has the potential to improve mCRPC outcomes. Transciptomic seq ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  10. Improving Patient Care Through Objective Monitoring of At-Home Repetitive Ritual Behaviors in Obsessive-Compulsive Disorder

    SBC: ADVANCED MEDICAL ELECTRONICS CORP            Topic: 104

    Project Summary Obsessive-compulsive disorder (OCD) is characterized by intrusive, distressing thoughts (obsessions) in response to which an individual feels compelled to perform a repetitive behavior (compulsions), which are performed in order to reduce the acute distress experienced by the patient but which perpetuate OCD symptoms. Effective treatment requires accurate reporting of compulsive be ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
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