List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Novel IL-15 Superagonist Therapy for Bladder Cancer

    SBC: Altor Bioscience LLC            Topic: 102

    DESCRIPTION provided by applicant Bladder cancer is the fifth most common cancer in the United States Over of patients initially present with non muscle invasive bladder cancer NMIBC confined to the mucosa of the bladder These patients are treated by tumor resection followed by intravesical chemotherapy or Bacillus Calmette Gu rin BCG therapy Despite treatment of NMIBC pat ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Cheap and fast ambient air monitoring of pesticides

    SBC: ISENSE, LLC            Topic: NIEHS

    DESCRIPTION provided by applicant Acute pesticide poisoning remains a vast health problem in the developed and developing world Domestically a study estimates that of every US agricultural workers suffer from acute pesticide poisoning On top of that long time effects have also been observed with an increased risk for lymphomas and prostate brain leukemia cervix and stomac ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Process Chemistry of Largazole, a Marine HDAC Inhibitor with Anticancer Activity

    SBC: Oceanyx Pharmaceuticals, Inc.            Topic: NCI

    DESCRIPTION provided by applicant Significance Colorectal cancer CRC remains an unmet need and is a significant challenge to the healthcare system as one of the leading forms of cancer in the United States affecting an estimated people and causing an estimated deaths in Estimates of base case for the medical care costs for colorectal cancer in were $ billion a ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Bone Conduction Testing for Newborn Hearing Screening

    SBC: Intelligent Hearing Systems Corp.            Topic: NIDCD

    DESCRIPTION provided by applicant This study aims to develop an improved neonatal hearing screening device that will incorporate novel testing procedures combining simultaneous air and bone conduction testing so that mild hearing losses andlt dB nHL are better and consistently detected The proposed device will address the current need for a more sensitive hearing screening tool by stimul ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Galectin 1: A novel small protein therapy for Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: NIAMS

    DESCRIPTION provided by applicant Duchenne Muscular Dystrophy DMD is a fatal muscle disease affecting in every male births DMD results from mutations in the gene encoding the dystrophin a kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and a transmembrane protein complex called the dystrophin associated glycoprotein ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. A mobile framework to measure ejection fraction by automated non-invasive analysi

    SBC: AVENTUSOFT L.L.C.            Topic: 102

    DESCRIPTION provided by applicant This SBIR Phase I project will develop a novel mobile framework to measure left ventricular ejection fraction as a marker for systolic dysfunction using automated non invasive analysis of cardiac signals Heart disease is the leading cause of death for men and women accounting for more than one third of all U S deaths In total costs associated w ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. IL-15 Superagonist Complex as an Immunotherapeutic for Multiple Myeloma

    SBC: Altor Bioscience LLC            Topic: 102

    DESCRIPTION provided by applicant Multiple myeloma MM is the second most commonly diagnosed hematologic malignancy with an estimated newly diagnosed cases and deaths due to MM in the United States in MM typically a disease of the elderly is a malignancy of clonal plasma cells in the bone marrow BM characterized by the presence of paraproteinemia destructive bone dise ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. RSK3 Anchoring Disruptor Therapy for Heart Failure

    SBC: ANCHORED RSK3 INHIBITORS, LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Pathological cardiac remodeling including myocyte hypertrophy and apoptosis and myocardial interstitial fibrosis constitutes a common pathway to heart failure in disease Despite current pharmacologic therapy and other advances that attenuate remodeling mortality due to heart failure remains high New more effective therapeutic options are desperately neede ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Identification of Borrelia burgdorferi diagnostic biomarkers in humans and nonhum

    SBC: DxDiscovery Incorporated            Topic: NIAID

    DESCRIPTION provided by applicant The number of Lyme disease cases in the US has been recently estimated by the CDC at cases year This is major public health concern Currently available diagnostics rely on detection of the antibody response serology to Borrelia burgdorferi the causative agent of Lyme disease However serological tests are not accurate during the early stages of Ly ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Clinical utility of serum biomarkers for the management of neonatal Hypoxic Ischemic Encephalopathy (HIE) on a point-of-care device

    SBC: BANYAN BIOMARKERS, INC.            Topic: NICHD

    DESCRIPTION provided by applicant Systemic asphyxia occurs in of births and can lead to hypoxic ischemic encephalopathy HIE Between and of neonates with HIE die or have permanent deficits Although hypothermia is the standard of care for HIE we cannot differentiate patients who respond to hypothermia from non responders The primary goal of this project is to conduct a proof ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government