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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Small Molecule targeting of NADPH oxidase in neutrophils

    SBC: P2D, INC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Acute lung injury (ALI) and Acute Respiratory Distress Syndrome (ARDS) are characterized by a rapid and severe respiratory failure, arising after clinical events including major surgery, trauma, multiple transfusions and sepsis. ALI/ARDS have an associated mortality of 40-80% and current pharmacological modalities have been unsuccessful in decreasing mortality. ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a BBB Model to Study Transendothelial Cell Migration

    SBC: Flocel Inc.            Topic: NIMH

    DESCRIPTION (provided by applicant): Increasing evidence indicates that systemic inflammation and the blood-brain barrier (BBB), which becomes the target of overreacting or misguided immune cells that determine BBB failure and immune extravasations into the brain parenchyma, are involved in the pathogenesis of neurological diseases such as meningitis, inflammation, Alzheimer's disease, and multipl ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  4. Discovery of Novel Anti-Inflammatory Phytochemicals on Human Cell Platforms

    SBC: DISCOVERYBIOMED, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Title: Discovery of Novel Anti-Inflammatory Phytochemicals on Human Cell Platforms Project Summary Statement The Problems: Complementary and alternative medicine (CAM) is an understudied scientific discipline. It is unappreciated that many biologically active and therapeutically beneficial compounds are derived from botanicals. Moreover, the scientific me ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  5. High-Throughput Ex Vivo Tumor Cell Motility Assay

    SBC: NANOFIBER SOLUTIONS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Gliomas are the most aggressive and least successfully treated brain tumors because of their distinctive ability to infiltrate surrounding brain tissue. Even if the bulk of the tumor is removed, migratory cells left behind are not detected by the immune system and resist current cytotoxic therapies. Tumor recurrence then typically involves a rapid and deadly ou ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  6. DEVELOPING/MARKETING AN ASTHMA SELF-MANAGEMENT PROGRAM

    SBC: Allergy And Asthma Consultants            Topic: N/A

    THE PURPOSE OF THIS STUDY IS THREEFOLD: PART I WILL LAST APPROXIMATELY THREE MONTHS; THE GOAL OF THIS SEGMENT WILL BE TO DEVELOP ALL COMPONENTS REQUIRED FOR A SELF-MANAGEMENT PROGRAM FOR ALL ASTHMATIC PATIENTS. THIS WILL ENTAIL, IN PART, REFINING AND VIDEOTAPING PORTIONS OF A PROGRAM WITH PROVEN EFFICIENCY, WHEEZERS ANONYMOUS. IN ADDITION, RELIABILITY AND VALIDITY OF PAPER-AND-PENCIL INSTRUMENTS U ...

    SBIR Phase II 1987 Department of Health and Human Services
  7. GLYCATED HEMOGLOBIN BY AUTOMATED AFFINITY CHROMATOGRAPHY

    SBC: ANATRACE, INC.            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  8. COMPOSITE, HOLLOW FIBER MEMBRANE OXYGENATION DEVICE

    SBC: ANATRACE, INC.            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
  9. ADAPTIVE CONTROL OF AUTOMATIC DRUG DELIVERY SYSTEMS

    SBC: Controlsoft Inc            Topic: N/A

    RECENT IMPROVEMENTS IN IMPLANTABLE PHYSIOLOGICAL TRANSDUCER TECHNOLOGY AND THE AVAILABILITY OF LOW-COST COMPUTATIONAL POWER HAVE GREATLY INCREASED INTEREST IN THE AUTOMATED CONTROL OF PHYSIOLOGICAL PARAMETERS IN THE RESEARCH LABORATORY AND IN CLINICAL THERAPY. THE OBJECTIVE OF THIS RESEARCH IS TO DEVELOP AND EVALUATE SAFE AND EFFECTIVE ADAPTIVE CONTROL SOFTWARE FOR THE AUTOMATIC REGULATION OF THER ...

    SBIR Phase I 1987 Department of Health and Human Services
  10. INITIATION-PROMOTION BIOASSAY IN MOUSE LIVER

    SBC: Environmental Health Research            Topic: N/A

    N/A

    SBIR Phase I 1987 Department of Health and Human Services
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