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SBC: ZANSORS LLC Topic: NICHD
DESCRIPTION provided by applicant This STTR grant is aimed to reduce pain from repeated needle pricks by improving the monitoring of glucose homeostasis GH in neonates by developing a real time glucose monitoring device The innovation utilizes a micro needle based lab on a patch platform invented by STTR partner George Washington University GWU GH is usually monitored by blood test via a ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: PARABON NANOLABS, INC. Topic: NIAID
DESCRIPTION provided by applicant There is a critical need for a safe and effective vaccine against HIV Decades of work have been invested in understanding the immune response to infection and different approaches have been taken to develop vaccines that are effective in preventing and treating the disease While effective in animal models none have been as effective in humans The immune ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
A cloud-based secure patient information exchange framework for managing treatment accessibility, utilization, quality, and outcomes in behavioral health clinicsSBC: Waldron International llc Topic: NIDA
DESCRIPTION In communities across the United States clinical populations exhibiting mental health and or substance abuse disorders face substantial challenges in accessing and receiving high quality and effective behavioral healthcare services Health Information technology HIT has been identified as an important component of improving access to behavioral healthcare in rural communities yet t ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: ADVANCED MEDICAL ELECTRONICS CORP Topic: NIA
DESCRIPTION provided by applicant Insomnia of sufficient clinical severity to meet diagnostic criteria is present in approximately of older adults nearly million individuals n the US alone If left untreated it can lead to increased rates of depression cognitive impairment and cardiovascular disease Treatment relies on pharmacotherapy such as sedative hypnotic therapy which is ass ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: VIBRANT CORP Topic: DLA15C001
Vibrant Corporation and Sandia National Laboratories (SNL) propose to apply Process Compensated Resonance Testing (PCRT) to the DLA's need for an NDI method to detect counterfeit, nonconforming and improperly processed materiel. PCRT collects and analyzes the resonance frequencies of a component to detect structural defects, characterize material, analyze population variation, monitor manufacturin ...STTR Phase I 2016 Department of DefenseDefense Logistics Agency
Novel Assay System and Analysis Algorithm in Detecting RNA Editing Events and Linked Splicing IsoformsSBC: Celetrix LLC Topic: NIDA
Abstract RNA editing is a process in which the genome encoded information is altered in RNA RNA editing is an efficient way to increase RNA complexity thereby fine tuning both gene function and dosage Adenosine to Inosine A to I editing is the most common type of RNA editing known in animals The cellular machinery recognizes inosine as guanosine so A to I editing of codons and splicing sign ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: FIREBIRD BIOMOLECULAR SCIENCES LLC Topic: 100
DESCRIPTION provided by applicant To many notably Craig Venter andquot synthetic biologyandquot means simply andquot synthesizing large amounts of DNAandquot This type of synthetic biology actually began in the andapos s when Caruthers introduced a phosphoramidite based solid phase DNA synthesis architecture This allowed ICI and the Benner group to synthesize complete genes encoding ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: TDA RESEARCH, INC. Topic: NIAID
Project Summary Abstract Development of Optimized Endectocide treated Bird Feed Formulations for West Nile Virus Control STTR Phase I Application PIs Brady Clapsaddle TDA Research Inc Dr Brian Foy Colorado State University West Nile Virus WNV is the leading cause of domestically acquired arboviral disease in the United States resulting in significant disease and death every year in both ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: ImageIQ, Inc. Topic: 300
DESCRIPTION provided by applicant Chronic viral hepatitis is clinically silent until development of cirrhosis and hepatic decompensation Decompensated cirrhosis is a precursor to liver failure and is associated with increased risk of severe esophageal bleeding significant cardiovascular events and death The gold standard for diagnosing cirrhosis is liver biopsy though problems with the pro ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: FIREBIRD BIOMOLECULAR SCIENCES LLC Topic: NIGMS
Commercial Polymerases to Create Receptors Ligands and Catalysts on Demand Firebird Biomolecular Sciences LLC University of Texas Steven A Benner Andrew D Ellington ABSTRACT Innovators at Firebird Biomolecular Sciences LLC have created several generations of an artificially ex panded genetic information system AEGIS that adds eight nucleobases that form four additional pairs Z P S ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health