Award Data

AbstractThe pathogenesis of Sickle cell diseaseSCDcomprises a complex interplay of factors associated with vascular endothelial activationintense inflammationand increased sickle cell adhesionMicrovascular occlusion in SCD is initiated by adhesion of sickle red blood cellsRBCsto the endotheliumleading to acute painful vasoocclusive crisisVOCand the clinical morbidity in SCDTreatment strategies inc ...

The broader impact/commercial potential of this STTR project is to chemically recycle carbon dioxide, which would otherwise be released to the atmosphere, to useful fuels and products thus providing a closed loop for production and emissions for many common products. Virtually every industry uses petroleum and/or natural gas, either through transportation or plastics (e.g., packaging), and there i ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project will be to improve the safety testing of new drugs for approval by the FDA. By decreasing the time and costs associated with safety testing, the product will make all classes of new drugs safer, less expensive and available to patients sooner. All new drugs must demonstrate that they are safe. One com ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project is to develop low-cost, high-performing feed additives for the swine feed market. Some of the current additives that supplement feed have detrimental side effects and/or made from raw materials that are considered toxic. Additives made from these toxic raw materials need to undergo substantial purific ...

We propose the development of a user-friendly software tool for estimating the electric field distributions within spacecraft enclosures based on the Power Balance (PwB) method and enhanced by a database of experimentally determined Absorption Cross-Sections (ACS) of common equipment, components and cables.The software will be built around an already developed PwB solver that determines the statis ...

Opterus proposes to develop braided thin ply composite tapes. The tapes will be braided from ultra-thin spread-tow unidirectional carbon and glass ribbons and will enable a new source and form factor for thin-ply textiles. The resulting tapes will be especially useful for thin high strain composite space deployable structures where they will allow bias plies in long parts without requiring seams. ...

The aim of the proposed program is to design metasurface structures to manipulate electromagnetic waves of extremelynbsp;different frequencies, from visible light to THz.

Suppression of noise from aircraft is a vital NASA goal, especially important for the vision of Urban Air Mobility. Small urban aircraft may utilize Distributed Electric Propulsion along with advanced structural and electric motor/storage technologies to achieve the necessary flight capability. However, these aircraft utilize propellers or fans to achieve the necessary thrust, with attendant commu ...

Emergent Space Technologies (Emergent) proposes to develop ROBOT, the Rules Oriented Blockchain Operations Transactor. ROBOT extends Blockchain technology to the space domain, enabling essential autonomy for distributed spacecraft resource scheduling and tasking. In the ground segment of federated systems, where NASA does not control all resources, ROBOT enables system users to securely and transp ...

Addressing the needs of Mars exploration missions in the NASArsquo;s strategic plan will require robust and effective autonomous collaborative operations between heterogeneous assets. These ldquo;swarmsrdquo; may consisting of ground rovers, atmospheric craft and Mars-orbiting satellites. To maximize the satisfaction of overall mission objectives, be tolerant of faults/anomalies, and minimize the ...