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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. User Adaptation of AAC Device Voices

    SBC: BIOSPEECH INC            Topic: NIDCD

    DESCRIPTION (provided by applicant): Augmentative and alternative communication devices with voice output (also known as Speech Generating Devices, or SGDs) enable individuals to speak by electronic means. Typical users of SGDs are individuals who have suffered from a stroke, traumatic brain injury, or who have neurodegenerative or neurodevelopmental disorders. In most cases, the user was able to ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  2. Black Bear Parathyroid Hormone as an Anabolic Agent for Bone

    SBC: PROTEOS, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Project Summary/Abstract. A clinical need exists for better osteoporosis treatments since only one anabolic therapy (truncated recombinant human parathyroid hormone 1-34, teriparatide/Forteo(R)) is commercially available. Bears possess the unique ability to prevent bone loss during physical inactivity (hibernation) by maintaining balanced bone remodeling; the b ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  3. PPAR-sparing/free Thiazolidinediones for Treatment of Diabetes

    SBC: Metabolic Solutions Development Company, LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): The overall objective of our proposed research is to discover a PPARg-free thiazolidinedione (TZD) which shows antidiabetic activity in a rodent model of Type 2 diabetes and demonstrates the necessary drug-like qualities to become a clinical candidate for human therapeutics. The insulin sensitizing agents of the TZD class are conventionally thought to operate t ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  4. Mitochondrial Dysfunction in HAART: Point of Care Tests

    SBC: MITOSCIENCES, INC            Topic: NIGMS

    DESCRIPTION (provided by applicant): Highly Active Anti-Retroviral Therapy (HAART) used to treat HIV/AIDS has serious side-effects, including metabolic complications from mitochondrial toxicities that can be life-threatening, and limit effectiveness and patient compliance. Adverse metabolic effects are now managed by adept clinicians who monitor patients closely for clinical symptoms and adjust t ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  5. Low cost custom synthesis microarray

    SBC: BIODISCOVERY LLC            Topic: NIGMS

    DESCRIPTION (provided by applicant): The results of our very successful phase I project showed that using projection lithography and off the shelf oligonucleotide synthesis reagents, we could in situ synthesize high density, high quality, very low cost, custom oligonucleotide microarrays on simple open substrates such as microscope slides. We also showed that using silver staining amplification it ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  6. Multipurpose reversible terminators

    SBC: FIREBIRD BIOMOLECULAR SCIENCES LLC            Topic: NHGRI

    DESCRIPTION (provided by applicant): This Phase 2 STTR application will allow the Foundation for Applied Molecular Evolution (FfAME) to complete its transfer of technology to Firebird Biomolecular Sciences LLC, allowing Firebird to commercialize nucleoside triphosphates where the 3'-OH groups are blocked by a 3'-ONH2 group. Triphosphates having this modification are accepted by DNA polymerases and ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  7. An Interactive Informed Consent Program for Cardiac Procedures

    SBC: ARCHIE MD INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Informed consent has become an essential component of the doctor-patient interaction. The informed consent process requires that patients not only be given information about proposed medical treatment, but that it be presented in an understandable way so the patient can make meaningful choices about medical alternatives. At the heart of the informed consent doc ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  8. Internet-based Fidelity Enhancement of MTFC

    SBC: Tfc Consultants, Inc.            Topic: NIMH

    DESCRIPTION (provided by applicant): The proposed project builds upon Phase I proof of concept efforts wherein the basic foundational components of an Internet-based Treatment Fidelity Monitoring System, the ITFMS, were created to assist MTFC consultants and implementing agencies to improve clinical outcomes by moving more efficiently towards and maintaining fidelity of program implementation. I ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  9. Awareness Enhancement and Monitoring Device for Treatment of Trichotillomania

    SBC: HAMZTEC, LLC            Topic: NIMH

    DESCRIPTION (provided by applicant): The goal of the proposed research is to further refine and evaluate an inconspicuous, awareness- enhancement and monitoring device (AEMD) which will assist the treatment of trichotillomania (TTM). TTM is associated with significant impairments in social functioning and often has a profound negative impact on self- esteem and well being. Conservative estimates s ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  10. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
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