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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Beyond Pillboxes: Medminding for Universal Drug Delivery


    DESCRIPTION (provided by applicant): Medication errors are now the leading cause of accidental death. Smart electronic devices are emerging to aid medication adherence with organizing, reminding, monitoring, and communicating medication use. Most are focused on bulk pills and are structured to dispense pills, remind at pill-time, monitor when pills are taken, or communicate pill histories to care ...

    SBIR Phase I 2011 Department of Health and Human Services
  2. FastFES Neural Prothesis for Stroke Ambulation and Rehabilitation

    SBC: CUSTOMKYNETICS, INC.            Topic: NICHD

    DESCRIPTION (provided by applicant): This FastTrack SBIR proposal aims to disseminate a Functional Electrical Stimulation (FES) technology for stroke ambulation and neuromotor rehabilitation. The FastFES paradigm integrates two rehabilitation approaches,fast-paced treadmill walking and FES, in a manner that has been shown to both improve gait kinematics when the stimulation is active and to impro ...

    SBIR Phase I 2011 Department of Health and Human Services
  3. Development of Percutaneous DLC for Total Cavo-pulmonary Assistance

    SBC: W-Z BIOTECH LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): The Fontan procedure is currently standard care for patients with complex single ventricle congenital heart defects. The Fontan procedure involves the creation of a cavopulmonary (CP) shunt connecting the inferior and superior vena cava (IVC and SVC) directly to the right pulmonary artery (RPA), diverting total venous return from the IVC/SVC directly to the PA ...

    STTR Phase I 2011 Department of Health and Human Services
  4. Generating Blood-based Diagnosis for Alzheimer Disease


    DESCRIPTION (provided by applicant): The present lack of blood-based diagnosis requires AD patients to be subjected to either invasive spinal fluid (CSF) tapping, expensive MRI or PET imaging, or arduous psychological testing, all unsuitable and costly forour elderly. Strategically, we shall address this unmet need by generating systemic biomarkers detectable in peripheral mononuclear cells (PBMC) ...

    SBIR Phase II 2011 Department of Health and Human Services
  5. Active Distributed Electrode Array Network for Electrical Stimulation Therapy

    SBC: CUSTOMKYNETICS, INC.            Topic: NICHD

    DESCRIPTION (provided by applicant): Transcutaneous electrical stimulation applications involving high numbers of stimulated muscles have been an area of growing interest in recent years. customKYnetics has been approached by research groups and stimulation application developers requesting high channel count stimulation devices for use in their spinal cord injury rehabilitation research studies ...

    SBIR Phase II 2011 Department of Health and Human Services
  6. A non-surgical embryo transfer (NSET) device for producing gene-modified mice

    SBC: PARATECHS CORP.            Topic: NCRR

    DESCRIPTION (provided by applicant): The use of research animals in research has been essential to development of vaccines and study of most human diseases. Modern rodent research is increasingly powerful with the ability to manipulate the genomes of miceand rats such that they closely mimic complex human diseases such as Alzheimer's and artherosclerosis. Generating transgenic mice and rats, ...

    SBIR Phase II 2011 Department of Health and Human Services
  7. Induction of Donor Tolerance in Renal Transplants

    SBC: REGENEREX, LLC            Topic: NIDDK

    DESCRIPTION: Renal transplantation is the preferred therapeutic approach for end organ failure. However, the chronic use of immunosuppressive agents is critical to prevent rejection. The drugs are costly ( 15,000-25,000/year) and have significant toxicities including opportunistic infection, an increased rate of malignancy, nephrotoxicity, and other end organ damage. The induction of donor-specifi ...

    STTR Phase II 2011 Department of Health and Human Services
  8. Intranasal Naloxone: An Opioid Overdose Antidote

    SBC: ANTIOP, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): There is a significant unmet medical need to provide additional pharmacologic treatments for treatment and prevention of opioid overdose. This Fast Track STTR project proposes to apply drug delivery technologies to develop a novel use for a nasally delivered pharmaceutical - naloxone (NLX) hydrochloride - for the emergency treatment of opioid overdose by emerge ...

    STTR Phase II 2011 Department of Health and Human Services
  9. Human Factors Analysis Support Tool (H-FAST)

    SBC: Tier 1 Performance Solutions, LLC            Topic: X1301

    Designing complex systems, such as those used by NASA, requires a coordinated effort among a variety of engineering teams. In order to be successful, the human-computer interactions in these systems need to follow a principle-based design process. In Phase II, TiER1 and Alion propose to continue development on HFE-AT, renaming it and creating a Human Factors Analysis Support Tool (H-FAST), which ...

    SBIR Phase II 2011 National Aeronautics and Space Administration
  10. State-of-the-art, Multi-Fidelity Modeling and Simulation (M&S) Tool for Nonlinear Aeroelasticity

    SBC: Advanced Dynamics, Inc.            Topic: A204

    Research is proposed for the development of a state-of-the-art computational aeroelastic tool. This tool will include various levels of fidelity and the ability to perform computational uncertainty quantification for data-driven risk analysis and certification. A number of novel reduced-order in time methods will be implemented into the code allowing for efficient and accurate aeroelastic simulati ...

    SBIR Phase II 2011 National Aeronautics and Space Administration

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