Award Data

DESCRIPTION (provided by applicant): Cardiac arrest claims over 450,000 lives per year in the United States alone. There is a high incidence of neurological complications amongst survivors, and these represent the leading cause of morbidity. Over the past several years, the care of these patients has been improved via the introduction of new systemic as well as neurospecific therapies. Speed of in ...

DESCRIPTION (provided by applicant): Current technology for HLA typing does not have rapid field response capability because it too expensive and is too complicated to be implemented in the context of a population-scale emergency. The ultimate goal of this proposal is to develop a simple, accurate, low cost method to perform complex HLA typing through development of an "HLA Chip" which will enable ...

Our solution is a generic "gateway/edge translation product", for Secure Legacy Application Integration with the NCES Enterprise Network structure (called “SLAIN”), that provides a modular implementation of the following capabilities to enhance Legacy systems and enable them to interact in a more Net-Centric role in support of the Navy and FORCEnet guidance: • IA interoperability (few legacy ...

DESCRIPTION (provided by applicant): The main objective of this project is to develop a contrast agent to allow noninvasive imaging and monitoring of breast cancer with molecular specificity. The basis of the proposed method is a combination of optoacoustic imaging, nanotechnology and molecular biology of cancer. Laser Optoacoustic Imaging System (LOIS) uses near-infrared laser pulses to genera ...

DESCRIPTION (provided by applicant): Magnetic Resonance Imaging (MRI) has become the gold standard for the quantitative assessment of cardiac structure and function. The key to imaging the moving myocardium is a reliable and robust electrocardiogram signal which, used as a "trigger," can provide images at specified phases throughout the cardiac cycle. Stronger field strength magnets, greater magne ...

DESCRIPTION (provided by applicant): Under current regulatory policies, chemicals that are believed to comprise both a significant exposure and health risk in the human population are selected to undergo testing for toxicity and carcinogenic potency. The traditional method for evaluating carcinogenic activity and chronic toxicity of a specific chemical has been the two-year bioassay. Due to re ...

This proposed Phase II effort will capitalize on recent advances in precision registration and coherent change processing of hyperspectral imagery (HSI) to significantly enhance the military’s ability to detect, identify and track changes on the ground from spacecraft or high-altitude aircraft. Existing HSI processing approaches that rely solely on spatial and spectral information fall short of ...

Impact Technologies, in cooperation with Standard Aero and Northrop Grumman, will lead an effort to develop a web-based software tool capable of optimizing the maintenance repair and overhaul work scopes associated with gas turbine engines that yield realistic cost estimates on a per engine flying hour basis, including post-maintenance performance metrics and expected time on wing predictions. Th ...

DESCRIPTION (provided by applicant): Addressing a major transfusion safety issue, as of March 2004, AABB statute 5.1.5.1 mandates testing of all platelet units for bacterial contamination. The only commercially available tests for this purpose in the U.S. are culture-based tests which require 48-72 hours to deliver a result. Such tests are useful only for apheresis platelet testing, but not for ra ...

Infrared missile domes are a demanding application for materials due to severe aero-thermal heating, requiring excellent thermal shock and abrasion/erosion resistance while maintaining a high transmittance. Currently, only single-crystal alumina (sapphire) meets these demanding criteria, though at a high cost due to the processing involved in producing sapphire domes. CeraNova’s nanocrystallin ...