Award Data

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project is to develop low-cost, high-performing feed additives for the swine feed market. Some of the current additives that supplement feed have detrimental side effects and/or made from raw materials that are considered toxic. Additives made from these toxic raw materials need to undergo substantial purific ...

The broader impact/commercial potential of this STTR project is to chemically recycle carbon dioxide, which would otherwise be released to the atmosphere, to useful fuels and products thus providing a closed loop for production and emissions for many common products. Virtually every industry uses petroleum and/or natural gas, either through transportation or plastics (e.g., packaging), and there i ...

Myocardial infarctionsMIor heart attacksischemic strokesISand peripheral artery diseasePADtogether considered cardiovascular diseaseCVDare all commonly caused by the same underlying pathologyatherosclerosisMIs and ISs are the leading causes of death and disability worldwideAtherosclerosis is a progressive pathology that develops asymptomatically over the course of many years as inflammatory plaque ...

The broader impact/commercial impact of this Small Business Technology Transfer Research (STTR) project is to reduce the environmental impact of agricultural production while optimizing net income to producers. Over-application of nitrogen fertilizer contributes to groundwater contamination via nitrate-nitrogen leaching, and puts substantial financial burden on rural municipalities and private wel ...

The broader impact of this Small Business Technology Transfer (STTR) Phase I project includes the development of new tools and methods for detecting and managing insect populations in the agricultural sector. The benefits of improved information about insect populations are substantial, including increased farm revenues through avoided pest damage and improved pollinator activity, and increased ac ...

AbstractThe pathogenesis of Sickle cell diseaseSCDcomprises a complex interplay of factors associated with vascular endothelial activationintense inflammationand increased sickle cell adhesionMicrovascular occlusion in SCD is initiated by adhesion of sickle red blood cellsRBCsto the endotheliumleading to acute painful vasoocclusive crisisVOCand the clinical morbidity in SCDTreatment strategies inc ...

This SBIR Phase I project aims to focus on the challenges neuroradiologists and neurosurgeons experience when visualizing complex brain aneurysms. Brain aneurysms, which occur in 2-3% of the population, are balloon-like dilations of a blood vessel supplying the brain which may rupture and result in severe headaches, paralysis, coma and death. Currently, radiologists viewing Magnetic Resonance Imag ...

The broader impact of this Small Business Technology Transfer (STTR) Phase I project will provide a low-cost wearable Internet-of-Things (IoT) device for upper extremity physical therapy rehabilitation. The project will contribute to the ultimate goal of helping patients suffering from stroke or joint-related injuries of the upper extremities. The project will result in a body of knowledge that ph ...

Accurate simulation of nuclear power plant behavior is necessary for both engineering and training applications. An engineering grade simulator, used for design, safety analysis and operations, is characterized by high fidelity, computational power, lack of real-time capability, and user non-interactive environment. By contrast, a training grade simulator, used for operator training and education, ...

Project Summary AbstractThe recent rapid expansion of genomic data greatly contributes to the understanding of disease development and progressionTo translate these genetic discoveries into clinical applicationswe need to develop therapeutic platforms that can specifically modulate the expression of disease related genes in vivoSmall RNAssuch as microRNAs and siRNAs function in messenger RNA silen ...