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STTR Phase II: Deep Learning Technology For The Microscopic Analysis Of Stained Cells Using Unbiased MethodsSBC: Stereology Resource Center, Inc Topic: BT
The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase II project is the development of software to help bioscientists analyze more tissue in less time and with higher accuracy and reproducibility. Currently, stereology studies require a trained technician to sit before a computer screen, making tedious manual counts (clicks) on hundreds to thousands of mic ...STTR Phase II 2019 National Science Foundation
SBC: CETYA THERAPEUTICS, INC. Topic: NHLBI
PROJECT SUMMARY The β-hemoglobinopathies are prevalent genetic blood diseases with few treatment options. It is estimate that 7% of the worldandapos;s population carries an abnormal hemoglobin gene with 400,000 infants born annually with a severe life threatening hemoglobinopathy. Drug mediated induction of normal, but developmentally silenced, fetal hemoglobin (HbF) expression reduces anemia and ...STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: BIOMIMETIX JV LLC Topic: 102
Ischemic stroke is a leading cause of death and disability in the United States. This often is attributable to thrombus formation at an atherosclerotic plaque or thromboembolism. Patients who present within 4.5 hours of symptom onset are eligible for thrombolysis with tissue plasminogen activator (tPA). This serves andlt;5% of victims. Recently, major advance has been made with proven efficacy fro ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: Science Take-Out, LLC Topic: R
ABSTRACT This supplement project will expand on our current STTR Phase I project in which we partnered with University of Rochesterandapos;s Environmental Health Sciences Center to develop three Science Take-Out vaping education kits. Our vaping education kits involve students in using hands-on activities and real-life scenarios to investigate the harmful effects of chemicals used in e-cigarette f ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: BERTEC CORP Topic: NIA
Falls are a significant source of early morbidity and mortality in the aging population, yet the neurological,sensory, and motor changes that lead to increased fall risk often escape early identification and intervention. Vital signs are commonly used in clinical settings to assess the cardiovascular system (blood pressure, heart rate), immune system (body temperature), and the respiratory system ...STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: Lacerta Therapeutics, Inc. Topic: 102
Glioblastoma (GBM) is the most lethal form of adult brain cancers with a median survival of andlt;15 months despite aggressive standard chemoradiation. GBM are formed by GBM stem-like cells (GSCs) - a major contributor to tumor recurrence and a natural focus for therapeutic development. There are two main reasons responsible for treatment failure: 1) high intra- and inter-tumor cellular and molecu ...STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: SIMMETRIX, INC. Topic: A15AT002
This project will provide state-of-the-art predictive capabilities for simulating systems central to advancing the U.S. Army’s modernization priorities related to long-range precision fires and future vertical lift platforms. The goals of the project are to: (1) Produce geometry and meshing technologies that support the modeling and discretization techniques needed to explicitly track evolving/i ...STTR Phase II 2019 Department of DefenseArmy
SBC: Space Sciences Innovations INC Topic: AF17CT03
Near-Earth space environment is hazardous to satellites. This harsh particle radiation can penetrate protective shielding, accumulate in sensitive materials and can damage even well shielded electronic components causing temporary malfunctions or a complete system/mission loss. The goal of the proposed work is to provide the Air Force with a state-of-the-art model of the outer zone energetic elect ...STTR Phase II 2019 Department of DefenseAir Force
SBC: DATA FUSION & NEURAL NETWORKS, LLC Topic: AF17CT02
The problem addressed in this effort is to automatically learn historical ephemeris space catalog time, position, and velocity entity track update error uncertainties (i.e., without track error covariances) and to automatically (e.g., without expert event labeling) produce: â€“ unmodeled non-gravitational space catalog update flags â€“ abnormal unmodeled catalog update flags with abnorma ...STTR Phase II 2019 Department of DefenseAir Force
Fast Response Heat Flux Sensors and Efficient Data Reduction Methodology for Hypersonic Wind TunnelsSBC: Innoveering, LLC Topic: AF17AT001
There is a DoD need for the development of robust sensors to obtain temporally and spatially resolved surface temperature and heat flux measurements on test articles in blowdown and continuous hypersonic wind tunnels. These micro-heat flux sensors are required in order to better understand the state of the boundary layer of a hypersonic vehicle; to better understand boundary layer instabilities; a ...STTR Phase II 2019 Department of DefenseAir Force