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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Innovative Manufacturing Techniques for Polysaccharide-Protein Conjugate Vaccines

    SBC: ENDOBIOLOGICS INTERNATIONAL CORP.            Topic: A03167

    This project develops a conjugate vaccine against Shigella flexneri 2a utilizing cGMP-compatible manufacturing processes. The antigenic component of the vaccine is deacylated-polysaccharide from the bacterial LPS that has an average of one O-antigen repeat unit per polysaccharide molecule. The polysaccharide is deacylated by a biological process, and has a core structure with intact phophosphory ...

    SBIR Phase I 2004 Department of DefenseArmy
  2. Innovative Manufacturing Techniques for Polysaccharide-Protein Conjugate Vaccines

    SBC: ENDOBIOLOGICS INTERNATIONAL CORP.            Topic: A03167

    There is need for a commercial vaccine against shigellosis because all groups of pathogenic Shigella have acquired resistance to antibiotics. Shigella conjugate vaccines have proven safe and protective in previous clinical trials, but obstacles associated with large-scale manufacturing of these subunit vaccines have apparently hindered commercial development. The present project uses a new and s ...

    SBIR Phase II 2004 Department of DefenseArmy
  3. Rapid Serological Diagnosis of Scrub Typhus Infections

    SBC: CHELATECH, INC.            Topic: N/A

    Infectious disease is a serious threat to military personnel in operations in third world countries. The ability to rapidly diagnose disease is critical to initiate treatment and to reduce troop mortality. This research addresses the DoD need to adaptstate-of-the-art technology to develop a rapid, field-usable assay capable of diagnosing scrub typhus infection. ChelaTech has developed new compo ...

    SBIR Phase I 2003 Department of DefenseArmy
  4. Developing a Seamless Integration Between Machine Learning Techniques and Rule-Based Classification of Remotely Sensed Imagery

    SBC: Visual Learning Systems, Inc.            Topic: N/A

    The Army has a critical need to accelerate and improve terrain analyses from remotely sensed imagery to support the increasingly mobile requirements of the Army Warfighter. Existing techniques for terrain analysis, topographic, and reproduction supportare slow, labor intensive processes that do not meet the needs of the Force XXI digital battlefield. Previous research has shown that incorporatin ...

    SBIR Phase I 2003 Department of DefenseArmy
  5. Developing a Seamless Integration Between Machine Learning Techniques and Rule-Based Classification of Remotely Sensed Imagery

    SBC: Visual Learning Systems, Inc.            Topic: N/A

    The proposed system will give an approach for increasing the speed, accuracy, and validation of feature extraction models while simultaneously creating an environment that allows both the flexibility for power users and the simplicity for the majority ofusers (novice users that can be trained and effective in a day) - and a mechanism that allows the two levels of users to seamlessly work together ...

    SBIR Phase II 2003 Department of DefenseArmy
  6. Shoot & Scoot Assistant (SASA)- A Cognitive Decision Aid for Crew Served Weapons

    SBC: 21ST CENTURY SYSTEMS, INC.            Topic: N/A

    "A military combat unit must "see" the battlefield better than the enemy, decide sooner than the enemy what to do, "move" to fight effectively and "shoot" to destroy the enemy. As the US Army moves toward weapons systems for the digital battlefield, newer,lighter weight and more capable hardware is emerging. These digital systems may not realize better "seeing", that is, situational awareness. Co ...

    SBIR Phase II 2002 Department of DefenseArmy
  7. SituSpace- Space battlespace awareness application

    SBC: 21ST CENTURY SYSTEMS, INC.            Topic: N/A

    "In response to Small Business Innovative Research solicitation A01-207, 21CSI is pleased to propose the development of a proof-of-concept software decision aid that aggregates space objects into a single, integrated space picture. Our decision aid,SituSpace, will be built from the bottom up to support the theater commander and his staff with a visual depiction of the space portion of the battles ...

    SBIR Phase I 2002 Department of DefenseArmy
  8. Eyekon: In-the-Situation Awareness for the Dismounted Warrior

    SBC: 21ST CENTURY SYSTEMS, INC.            Topic: N/A

    "The goals of an enhanced mobile infantry, a weapons system that leaves the warrior with his whole mind free to handle his weapons and notice what is going on around him, as expressed in Heinlein's timeless Starship Troopers is becoming a reality todaythrough the innovative progress being made by the U.S. Army's 21st Century Land Warrior program. However, the current Land Warrior system does not ...

    SBIR Phase I 2002 Department of DefenseArmy
  9. Resonant-Mixing of Gelled Propellants

    SBC: RESODYN CORPORATION            Topic: N/A

    "Gelled bipropellants provide advantages over liquid or solid gels. The conversion of advanced liquid oxidizers and fuels to gel greatly increases the safety of storage and use of bipropulsion materials in missile systems. Operational advantages of thegelled propellents over solid fuels include the ability to modulate fuel burn rate. The deliverable for this Phase II proposal is an advanced mix ...

    SBIR Phase II 2002 Department of DefenseArmy
  10. Innovative Sonic Technology for Ex-Situ Treatment of Mercury Contaminated Waste

    SBC: RESODYN CORPORATION            Topic: N/A

    A novel combination of technologies is proposed by Montec Research to improve ex situ mercury remediation. The combination of acoustic agitation, iodine leaching chemistry, and real-time management of leach oxidation potential will allow mercury to be extracted economically from soils, sediments, and debris. Additional residue-washing steps are proposed to help residues pass the Universal Treatmen ...

    SBIR Phase I 2001 Environmental Protection Agency

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