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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. A Non-Contact Optical Patient and Beam Dosimetry System for Continuous in vivo Radiotherapy Verification

    SBC: DoseOptics LLC            Topic: 102

    Abstract Optical Cherenkov video imaging of body anatomy and dose delivery can be used now to map out radiotherapy beam incidence upon the patient tissuedirectly visualizing the radiation dose deposition on the patient in real timeThis could serve as a non contact workflow tool for verification for daily fractionated radiation therapyallowing capture of all treatmentsall the timeDoseOptics has dev ...

    SBIR Phase I 2018 Department of Health and Human Services
  2. STEM Interactive Digital Tool to Educate and Promote Hearing Health and Science for 4th to 7th Grade

    SBC: CREARE LLC            Topic: 500

    PROJECT SUMMARY ABSTRACT The National Research Council recognizes that serious computer games can support new inquiry based approaches to science instructionproviding virtual laboratories or field learning experiences that overcome practical and logistical constraints to student investigationsWith the nationally recognized need to encourage and enhance education in the ScienceTechnologyEngineering ...

    SBIR Phase II 2018 Department of Health and Human Services
  3. OnTRACK: Mobile Application for Pediatric Post-TBI Patient Management

    SBC: CREARE LLC            Topic: NCIPC

    PROJECT SUMMARYCreare and its clinical and research partners propose to develop a software platformOnTRACKOnline Treatment Recovery Assistance for Concussion in Kidsfor children and adolescents recovering from concussion or mild traumatic brain injurymTBIThe platform includes a mobile applicationappfor the patients and their care teamparentsteacherscoachesetca database serverand a decision support ...

    SBIR Phase I 2018 Department of Health and Human Services
  4. Supine Breast MRI Standardization for Breast Cancer Locator

    SBC: CairnSurgical, Inc.            Topic: 102

    PROJECT SUMMARY ABSTRACTCairnSurgicalInca Dartmouth spin off companywill standardize supine breast MRI to streamline production of the Breast Cancer LocatorBCLas a cancer localization device for use in breast conserving surgeryBCStoieliminate wire localizationa moderately effectivesomewhat costly and certainly inconvenient procedure for patients and surgeonsand concomitantly toiireduce positive ma ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. DRIVEN: Accelerating Medical Entrepreneurship in the Northeast

    SBC: CELDARA MEDICAL, LLC            Topic: 500

    Project Summary This project describes the formationlaunch and operation of the DRIVEN Accelerator Hubwith the express goal of reducing morbidity and mortality by increasing the number of medical entrepreneurs and their level of competencyThe Hub is focused on the Northeast andin collaboration with similar Hubswill contribute nationwideIt willin a facilecompleteand accessible wayprovide the knowle ...

    STTR Phase I 2018 Department of Health and Human Services
  6. Probe for Quantitative Fluorescence

    SBC: InSight Surgical Technologies LLC            Topic: 105

    PROJECT SUMMARY ABSTRACTInSight Surgical TechnologiesLLCis a newly formed start up founded by senior members of an NIH funded research collaboration involving faculty at Dartmouth and TorontoIn this Phase I SBIR applicationfeasibility of a disposable fiber optic probe connected to commercial ready instrument design will be demonstrated as progress towards realization of a near term medical product ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. Non-surgical treatment option for pelvic organ prolapse

    SBC: Reia, LLC            Topic: NICHD

    Project SummaryAbstract Reia is working to address a prevalent gynecological conditionpelvic organ prolapsePOPwhich affects more thanof women over the age ofPOP occurs when the pelvic floor connective tissue and muscles weakenallowing the uterus or vaginal walls to descendIn extreme casesthe uterus descends through the opening of the vagina and hangs outside of the bodyPOP can be treated non surgi ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. Targeting leukocyte metabolism to treat human autoimmune disease

    SBC: Immunext, Inc.            Topic: R

    ImmuNext has defined an anti MCTmonoclonal antibodymAbthat will be developed for the treatment of human autoimmune diseaseThe membrane monocarboxylate nutrient transporter SLCAMCTis a multi pass transmembrane protein responsible for the facilitated transport of critical metabolitesincluding products of glycolysislactatepyruvate and ketonesOur strong preliminary data support the tenet that mAbs tha ...

    SBIR Phase II 2018 Department of Health and Human Services
  9. Complex 3-Dimensional in vitro Human Skin Tissue Models for Scleroderma

    SBC: CELDARA MEDICAL, LLC            Topic: NIAMS

    PROJECT SUMMARY Sclerodermasystemic sclerosisSScis an autoimmune disease of unknown etiology that is characterized by vascular dysfunctionfibrosisand inflammationOne in three patients dies withinyears of diagnosisgiving SSc the highest case fatality rate of any systemic autoimmune diseaseA lack of biologically relevant SSc disease models has created a critical unmet need for more efficient preclin ...

    SBIR Phase II 2018 Department of Health and Human Services
  10. Optimized Dry Powder Formulation and Delivery for Inhaled Clofazimine

    SBC: CREARE LLC            Topic: NIAID

    Treatment regimens for multi drug resistant tuberculosisMDR TBinvolve a spectrum of second tier drugs delivered over a long periodoften over a yearA drug that has shown promise in short regimenssuch as the Bangladesh regimenis oral ClofazimineCFZbut tolerance to oral CFZ is limitedInhaled delivery could potentially limit adverse effects and maximize delivery to the infected pulmonary tissueFormula ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health

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