Award Data

DESCRIPTION (provided by applicant): Coccidioidomycosis is a regional fungal disease in desert areas of the Southwestern U.S. and is of particular importance to Arizona and California. The importance of this disease extends beyond the endemic areas due to extensive travel to these locations. Infection with Coccidioides spp. may cause illness ranging from a mild, self-limiting, pulmonary syndrome ...

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ABSTRACT: Intrauterine infection and chorioamnionitis are common complications of pregnancy associated with significant maternal, perinatal, and long-term adverse outcomes. Adverse maternal outcomes include postpartum infections and sepsis while adverse infant outcomes include stillbirth, premature birth, neonatal sepsis, chronic lung disease and brain injury leading to cerebral palsy and other ne ...

DESCRIPTION provided by applicant Inflammatory disease states are leading causes of death and disability and a major cost to healthcare in the United States There is an epidemic of death and hospitalizations due to adverse effects from NSAIDs TAI LCx Turmeric Anti Inflammatory Lipophilic Component X is a novel anti inflammatory discovered in previously unrecognized pharmacologically activ ...

The reliability of electronic packages is of paramount concern in todays electronics industry, and ensuring their thermomechanical integrity is necessary to achieve this reliability. However, this task has become more challenging with miniaturization and the introduction of new materials. Thermal stresses in electronic packages continue to be one of the leading causes of device failure. The pro ...

In the proposed effort, we will develop the fundamental building blocks to develop a high performance, low Size, Weight, and Power (SWaP) ultrashort pulse Femtosecond Direct Diode Laser System (fsDDLS) capable of generating and sustaining filaments/plasma channels in the atmosphere ahead of a vehicle in hypersonic flight to reduce drag, heating, and displace shock. Approved for Public Release | 22 ...

DESCRIPTION (provided by applicant): Osteoarthritis is a leading chronic disease in older adults characterized by degeneration of articular cartilage of the joints in hands, spine, knees and hips. Tissue injury and pain are caused by conversion of arachidonic acid in joints to such inflammatory compounds as PGE2 and LTB4 by cyclooxygenase (COX) and 5-lipoxygenase (5-LO) enzymes. Conventional no ...

Because of the repetitive trauma to the upper extremities that results from wheelchair propulsion, the prevalence of pain and injury in manual wheelchair users is alarmingly high. By understanding the mechanisms in the development of arm pain, we can begin to prevent the pain. The SMART(Wheel) is a tool that enables direct measurement of the forces and torques applied by wheelchair users to the pu ...

Because of the repetitive trauma to the upper extremities that results from wheelchair propulsion, the prevalence of pain and injury in manual wheelchair users is alarmingly high. By understanding the mechanisms in the development of arm pain, we can begin to prevent the pain. The SMART(Wheel) is a tool that enables direct measurement of the forces and torques applied by wheelchair users to the pu ...

The goals of Phase I including developing a fundamental model that describes H2O2 decomposition, design strategies for developing a thermal decomposer, and an assessment of the feasibility of these strategies. Key to development of a thermal decomposer isa predictive model that prevents device burnout and peroxide detonation over a range of flow rates.The Technical objectives for developing a fun ...