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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Infrared sensor for screening of emerging contaminants in water

    SBC: MAX-IR LABS INCORPORATED            Topic: 113

    Project Summary/Abstract The goal of this project is to develop a sensor for monitoring of per- and polyfluoroalkyl substances (PFAS) in water to help achieve universal and equitable access to safe and affordable drinking water for all. PFAS have received particular attention in the past decade due to their persistent and bio-accumulative nature and high toxicity. The proposed sensor is based on i ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  2. Brief Personalized Feedback Intervention for Latinx Hazardous Drinkers: A Community-Based Intervention

    SBC: HEALTH BEHAVIOR SOLUTIONS INC            Topic: 450

    PROJECT SUMMARY/ABSTRACT Despite being one of the largest and fastest-growing demographics in the United States (US), Latinx persons experience striking health disparities, particularly in terms of hazardous drinking and co-occurring elevated anxiety. The co-occurrence of these risk factors contributes to worse physical/mental health outcomes among Latinx individuals. Few interventions to date hav ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  3. A Novel Bacterially-derived Product to Enhance Immunity and Response to Immune Checkpoint Therapy

    SBC: AUMENTA BIOSCIENCES, INC.            Topic: NIAID

    Abstract Aumenta is developing a product derived from two commensal bacterial species for use as an innovative immunologic therapy. The product is designed to augment multiple arms of the immune system, offering a safe, novel and innovative therapy for unmet needs in treating infectious disease (e.g. fungal infections) and enhancing the bodyandapos;s response to immuno-oncology therapies (e.g. imm ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  4. Using Cardiac Targeting Peptide to deliver miRNA for molecular reversal of heart failure

    SBC: VIVASC THERAPEUTICS INC            Topic: NHLBI

    PROJECT SUMMARY/ABSTRACT Heart failure (HF) is a common disease with well-documented morbidity and mortality that affects approximately 23 million people globally, including 6 million in the US. Current HF medications such as Angiotensin Converting Enzyme (ACE) Inhibitors or Angiotensin Receptor Blockers (ARBs) treat the symptoms of HF versus the root cause of the disease, which includes stressed ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  5. Developing Novel REV-ERB Agonists for the Treatment of Neuroinflammation in Alzheimer's Disease

    SBC: PELAGOS PHARMACEUTICALS, INC.            Topic: NIA

    Alzheimer’s Disease (AD) is a progressive neurodegenerative disease with clinical hallmarks such as memory loss, cognitive impairment, and dementia. AD affects over 5 million American and is the 6th leading cause of death; these numbers will rise dramatically as the US aging population increases. Given the continued failures and controversies of AD drugs in clinical trials, it is critical to ide ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  6. A novel PEDF peptide mimetic for diabetic retinopathy

    SBC: SKYRAN BIOLOGICS, INC.            Topic: NEI

    Abstract The overall goal of Skyran Biologics is to develop a potent topical therapeutic for diabetic retinopathy (DR), a leading cause of vision loss globally. Our research team identified Pigment Epithelium-Derived Factor (PEDF) and showed it is expressed in the eye and provides significant protection to the injured retina. Since its discovery, we identified a 44-mer N-terminus bioactive region ...

    STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  7. Momitor: Wearable Technology for Early Detection of Postpartum Hemorrhage

    SBC: Vasowatch LLC            Topic: NHLBI

    Abstract: Postpartum hemorrhage (PPH) is the leading cause of maternal death worldwide and disproportionately affects minority populations. PPH is defined as a large loss of blood within 24 hours of birth. If detected early enough, effective clinical management solutions exist that significantly reduce mortality. Current standard of care for detecting PPH rely on vital sign monitoring and visually ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  8. An additive solution to expand the lung transplant organ pool

    SBC: Peroxitech LLC            Topic: NHLBI

    PROJECT SUMMARY Major challenges in the field of lung transplantation are the low availability of healthy donor lungs (graft) and the damage to donor lungs post-transplant. These arise due to inflammation and oxidative damage initiated during the graft storage period. Among the multiple strategies employed to improve lung availability and transplant outcome are short storage times (comprising of a ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  9. New Electrodes for Enabling Inclusive EEG Monitoring in Black Populations

    SBC: Precision Neuroscopics, Inc            Topic: NICHD

    Electroencephalography (EEG) -- a neural sensing modality essential for diagnosis of epilepsy, stroke, brain injuries and other neurological disorders -- is not accessible to individuals with coarse and curly hair common in Black populations. The springiness of these hair-types makes it difficult to maintain a good electrodes-scalp contact. Consequently, Black patients are denied the same quality ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  10. 3D Image Analysis Software for Breast Reconstruction Surgical Planning, Outcome Assessment and Clinical Consultation

    SBC: SOFT IMAGING LLC            Topic: NCI

    AbstractBreast cancer is the second leading cause of cancer death in American women. Breast reconstruction surgery is an important component of the breast cancer treatment process, that is used to rebuild a breast form that has been removed due to cancer surgery. It is integral to improving the cancer patient's health-related quality of life. However, planning and evaluation of the surgery are don ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
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