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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A novel 3D cell culture human uterine contractility assay for high-throughput scr

    SBC: CHEMOSEN3D INC            Topic: NICHD

    DESCRIPTION (provided by applicant): Several disorders in reproductive medicine are results of changes in smooth muscle contractile activity. Increased myometrial contraction can lead to preterm labor, which affects 12% of the US population. However, the mechanisms involved in the transition from uterine quiescence to contractility at the onset of labor are not well-known. As a result, the managem ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. POC 2-D Diffusion Assay for self-monitoring of BNP

    SBC: SENTILUS            Topic: NHLBI

    DESCRIPTION (provided by applicant): The objective of this STTR proposal is to develop a 2-D diffusion point-of-care assay (POC) for B-type natriuretic peptide (BNP). The primary goal of the proposed work is to create a test format that will allow patientswith chronic heart failure to quantitatively self-monitor serum levels of BNP. Determination of baseline level of BNP and changes in this level ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. A smart needle guide template for MRI-guided transperineal prostate biopsy

    SBC: PHYSICAL SCIENCES INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Physical Sciences Inc. (PSI) and the Surgical Navigation and Robotics Laboratory (SNR) at Brigham and Women's Hospital (BWH) propose to develop and test a Smart Template to guide transperineal targeted prostate biopsiesand subsequent therapy under magnetic resonance imaging (MRI). The project aims to solve the problem of poor diagnostic yield in prostate b ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Ex vivo purging strategy for treatment of multiple myeloma

    SBC: DNATRIX INC            Topic: NCI

    DESCRIPTION (provided by applicant): The ultimate goal of this application is to develop a novel ex vivo purging method using myxoma virus (MYXV), a rabbit-specific poxvirus, to improve the clinical outcomes in treatment of multiple myeloma (MM). MM is aclonal plasma cell malignancy that has to date resisted essentially all therapeutic strategies. Currently, the standard of care for patients wit ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Novel Pharmacotherapeutic Bioadhesive Patch for Oral Ulcerations

    SBC: POST OAK PHARMACEUTICALS, INC.            Topic: NIDCR

    Project Summary Oral ulceration is one of the most commonly encountered oral diseases, with an estimated prevalence of 4% in the USA. Managing large or multiple ulcers that are caused by diseases of unknown etiology, such as erosive lichen planus or aphthous ulcers which affect 25% of the population worldwide, is also a challenge to dentists and specialists. Ulceration of the oral mucosa can caus ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Developing Inhibitors of the STARS/SRF Pathway for Treatment of Type 2 Diabetes

    SBC: Jenesis Biosciences LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): Type 2 diabetes (T2D) has reached epidemic proportions in the United States, affecting an estimated 8.3% of the population. Unfortunately, the majority of individuals with diabetes continue to have suboptimal control ofglucose, therefore new and improved approaches to prevention and treatment are sorely needed. Dr. Mary Elizabeth Patti's laboratory at the ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. High Throughput Manufacturing of Monodispersed Nanoparticles for Biomedicine

    SBC: CHEMTOR, L.P.            Topic: NIA

    DESCRIPTION (provided by applicant): This Phase I Small Business Technology Transfer (STTR) project focuses on the development of a new platform manufacturing process for large-scale preparation of monodispersed polymeric nanoparticles (NPs) suitable for biomedical applications through the use of a large-scale fiber fluidic system. Although laboratory processes for reproducible synthesis of polyme ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Non-Dispersive Reaction and Separation Processes for Pharmaceutical Synthesis

    SBC: CHEMTOR, L.P.            Topic: 300

    DESCRIPTION provided by applicant A number of pharmaceutical reactions and wash processes involve interaction between immiscible phases within reactors or extraction equipment Multi phase synthesis processes have been traditionally been carried out through dispersion of one of the phases into the other in the form of droplets Such arrangement increases the surface area of interaction thereby ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Microscale Detector Materials for Covert, Ubiquitous Radiation Detector

    SBC: RADIATION MONITORING DEVICES, INC.            Topic: DTRA14B004

    The proliferation of nuclear and radiological weapons of mass destruction is a serious threat in the world today. The goal of this proposal is to develop a new, very low cost radiation detection technology that will be useful for detection and for surveillance of individuals who have been near radioactive materials. The technology can also be used for dosimetry, and will provide the technology for ...

    STTR Phase I 2015 Department of DefenseDefense Threat Reduction Agency
  10. Large area, high efficiency, extremely light-weight portable neutron Detector

    SBC: TRITON SYSTEMS, INC.            Topic: DTRA14B005

    A drop-in 3He-tube replacement technology for thermal neutron detection does not exist today. It is critical for homeland security and nuclear safeguards applications. In this program, Triton Systems proposes to develop a light-weight, large-area, high efficiency portable neutron detector for passive interrogation using an innovative gas detector structure. The resulting 3He-free thermal neutron d ...

    STTR Phase I 2015 Department of DefenseDefense Threat Reduction Agency
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