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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Expanding teleconsent capabilities to improve clinical research recruitment
SBC: Doxy.me Inc. Topic: NLMLack of recruitment of qualified research participants into clinical trials remains to be one of the most important issues in clinical research Studies often struggle to meet recruitment goals on time resulting in costly time extensions underpowered results and in some cases early termination Many reasons attribute to suboptimal recruitment including the challenges related to informing and c ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Gold nanoparticle laser warming of cryopreserved zebrafish embryos
SBC: NANOCOMPOSIX, INC. Topic: ODProject Summary Abstract In the past decade laboratories around the world have produced tens of thousands of mutant transgenic and wild type zebrafish lines for a wide range of genetic and biomedical research Maintaining all of these valuable genotypes is expensive risky and beyond the capacity of even the largest stock centers Cryopreservation of zebrafish sperm eggs and embryos is vital ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
I- Corps Administrative Supplement to Novel Reagents for Breast Tumor SPECT Imaging R41CA217546
SBC: Cavatar LLC Topic: NCIPROJECT SUMMARY Early cancer detection and diagnosis are critical for patient survival and treatment successFor the imaging of breast and other solid tumorsthe diagnostic power of advanced imaging techniques such as SPECT could benefit tremendously from improved contrast agents that rapidly and selectively accumulate in tumor lesions and produce high tumor to background signal ratiosWe are develop ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
improving Cas9 mediated homologous recombination in pluripotent stem cells
SBC: APPLIED STEMCELL, INC. Topic: 200DESCRIPTION provided by applicant Gene correction therapy is one of the most important application directions in regenerative medicine Scientists are exploring various approaches to introduce targeted mutations corrections to pluripotent stem cells PSCs to establish disease models and or to develop therapeutic agents Emerging technologies such as Zinc Finger Nucleases ZFNs Transcription ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications
SBC: GENECAPTURE, INC. Topic: CBD15C001The modern warfighter faces the constant threat of endemic infections, multi-drug resistant bacteria and Biological Warfare Agents. In order to provide accurate front-line treatment that will curtail the overuse of antibiotics, a rapid and robust molecula
STTR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense -
Innovative Mitigation of Radiation Effects in Advanced Technology Nodes
SBC: RELIABLE MICROSYSTEMS LLC Topic: DTRA16A003Establish a radiation-aware analysis capability in a commercial EDA design flow that will enable first-pass success in radiation-hardened by design (RHBD) for DoD ASICs in much the same way that existing EDA design suites ensure first pass functionality and performance success of complex ASICs destined for commercial applications. Layout-aware, calibrated single-event radiation models that captur ...
STTR Phase I 2016 Department of DefenseDefense Threat Reduction Agency -
Innovative Tools for Three Dimensional Traction Force Microscopy of Single Cells
SBC: SIMMETRIX, INC. Topic: 102Project Summary Tractions exerted by individual cells on their surroundings play a critical role in mechanical events in biology such as tissue contraction folding cell shape changes or cell movements and in many basic cellular functions such as biochemical signaling proliferation and differentiation These processes are in turn implicated in the progression of diseases like cancer atherosc ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Integrated Platform for Mass Spectrometric Studies of Protein Structure
SBC: PROTEIN METRICS INC Topic: 100Summary Technology for studying the higher order structure HOS of biomolecules encompasses some of the most important tools in all of science and is a highlighted NIGMS research topic Mass spectrometric methods for studying HOS include oxidative footprinting and other methods to covalently label amino acid side chain functional groups and also hydrogen deuterium exchange HDX on protein bac ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Integrated tools for higher order structure determination by cross link analysis
SBC: PROTEIN METRICS INC Topic: 100Summary The use of mass spectrometry MS for quantitative protein characterization has increased dramatically identifying and quantifying thousands of proteins is no longer a heroic task nor is characterizing therapeutic proteins in detail Due to widely available software quantitative mass spectrometry has become routine and widely used for addressing questions in basic biology translational ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Investigation of antibody drug conjugates of a novel target
SBC: WNTRIX INC Topic: NCIPROJECT SUMMARY Antibody drug conjugates ADCs are monoclonal antibodies mAbs that are covalently linked to cell killing drugs and have emerged as a major modality in anti cancer treatment This approach combines high specificity of mAbs against their antigen targets with highly potent cytotoxic drugs resulting in armed mAbs that deliver the payload drug to tumor cells with enriched levels ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health