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The Award database is continually updated throughout the year. As a result, data for FY22 is not expected to be complete until September, 2023.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Skin Sympathetic Nerve Activity and Cardiac Arrhythmias

    SBC: ARRHYTHMOTECH            Topic: NIDA

    DESCRIPTION provided by applicant The objective of this Phase II STTR grant application is to continue the R Randamp D efforts initiated in Phase I The long term objective for Arrhythmotech is to develop and market an instrument for the simultaneous recording of sympathetic nerve activity SNA and electrocardiogram ECG using electrodes on the skin This method neuECG was discovered in Dr ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Simultaneous Proportional and Independent sEMG Based Hand Wrist Prosthesis Control

    SBC: LIBERATING TECHNOLOGIES INC            Topic: NICHD

    DESCRIPTION provided by applicant Surface electromyogram sEMG controlled powered hand wrist prostheses are used by upper limb amputees to return partial upper limb function Conventional transradial prostheses can use surface EMG amplitudes from the residual forearm flexors and extensors to control hand closing and opening respectively Additional degrees of freedom DoFs e g wrist rota ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Using Magnetic Levitation for Non-Destructive Detection of Defective and Counterfeit Materiel

    SBC: Nano Terra, Inc.            Topic: DLA15C001

    The introduction of substandard or counterfeit materials into the DoD supply chain can have extremely expensive, and potentially life threatening, consequences. Current techniques used to detect nonconforming materiel can be destructive (e.g., manual sectioning and inspection of a part), time consuming and expensive (e.g., micro-computed tomography, ultrasound), or provide only limited informatio ...

    STTR Phase I 2016 Department of DefenseDefense Logistics Agency
  4. Development of a kit for characterization of cellular energetics in single cells in cell and tissue cultures based on the measurement of the absolute magnitude of the mitochondrial membrane potential

    SBC: Gerencser, Akos            Topic: R41

    DESCRIPTION provided by applicant Altered cellular energetics contributes to human disease in general physiological aging and chronic diseases in particular including cancer neurodegeneration ischemic heart disease and type diabetes Pathological changes affecting the individual may arise only in specific cells of a tissue and potentially in a heterogeneous manner To advance basic resea ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Assessment of the glucagon receptor blocker REMD-477 on insulin requirements in type 1 diabetes

    SBC: REMD BIOTHERAPEUTICS INC            Topic: NIDDK

    DESCRIPTION provided by applicant Fast Track Insulin remains the primary and often the only treatment for type diabetes mellitus T D However it is associated with chronic iatrogenic hyperinsulinemia secondary hyperlipidemia higher incidence and severity of cardiovascular complications and life threatening hypoglycemia events A higher mortality vs due to cardiovascular ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. A universal vaccine for the prevention of meningococcal meningitis in Africa

    SBC: Omvax, Inc.            Topic: R

    For more than years sub Saharan Africa has suffered with high rates of endemic meningococcal disease and periodic epidemic epidemics involving over cases In a low cost serogroup A polysaccharide protein conjugate vaccine MenAfriVac was introduced in the region The vaccine confers protection against serogroup A MenA disease as well as asymptomatic nasopharyngeal MenA carria ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Temozolomide Perillyl Alcohol Conjugate as Treatment for Recurrent Malignant Brain tumors

    SBC: NEONC TECHNOLOGIES INC            Topic: BT

    DESCRIPTION provided by applicant Glioblastoma multiforme GBM the most common and malignant of all gliomas has a median survival time of months Standard of care chemotherapy using temozolomide TMZ is effective initially but the GBM inevitably recurs and these recurrent tumors are resistant to TMZ There are currently no effective treatment options for patients with TMZ resistant ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Protection and Treatment of the Ocular Surface Barrier

    SBC: PROTERIS BIOTECH INC            Topic: N

    DESCRIPTION provided by applicant Dry eye a group of disorders that affects million people over the age of in the USA today is characterized by inadequate hydration and lubrication of the ocular surface The final common pathway for all types of dry eye is disruption of the ocular surface barrier which can be assessed by quantifying uptake of water soluble dyes applied topically to the ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Antibody targeting of ADAM for treatment of triple negative breast cancer

    SBC: ADECTO PHARMACEUTICALS INC            Topic: NCI

    DESCRIPTION provided by applicant Triple negative breast cancers TNBCs account for of breast cancer deaths and lack targeted therapies Drs Sonenshein Mineva and Romagnoli and their co workers recently identified the non essential cell surface protein ADAM A Disintegrin and Metalloprotease as a pivotal promoter of breast tumor growth and metastasis and validated it as a target o ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Data Driven Intent Recognition Framework

    SBC: Other Lab Inc.            Topic: NSF13599

    A critical aspect of exoskeleton control that has to date introduced a performance limitation is the ability of the exoskeleton to recognize the intent of the operator so it can apply assistance to their desired motion. This intent recognition effort is typically solved using ad-hoc methods where subject matter experts make design decisions and tune transitions to identify intended maneuvers as re ...

    STTR Phase II 2016 Department of DefenseSpecial Operations Command
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