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DESCRIPTION provided by applicant This Phase I STTR in response to RFA HD andquot Non or Minimally Invasive Methods to Measure Biochemical Substances during Neonatal and Perinatal Patient Care and Researchandquot develops and tests Baby Gentle Stick BGS a handheld device to decrease the distress of repeat blood sampling in neonates BGS combines delivery of vibration induced ane ...

DESCRIPTION provided by applicant In nearly million new cancer cases are estimated to occur in the US where nearly two thirds will have treatment by radiation therapy In current clinical practice organ contour delineation on medical images is still performed with low levels of automation due to lack of highly automated commercial contouring software This deteriorates therapy plann ...

DESCRIPTION provided by applicant Parkinsonandapos s disease PD is a neurodegenerative disorder characterized by motor function and eventually cognitive decline GM depletion is validated as a therapeutic target for Parkinsonandapos s disease PD in clinical studies in which GM replacement stabilized motor function loss and may be disease modifying However GM has poor pharmacologic prop ...

DESCRIPTION provided by applicant Optical microscopy is the most commonly used imaging technique in life and material sciences however the spatial resolution of any standard microscope is fundamentally limited by the diffraction of light waves which for visible light restricts spatial resolution to nm Surpassing the diffraction limit significantly impacts several disciplines such as me ...

DESCRIPTION provided by applicant Preclinical evaluation of treatment strategies for retinal neurodegenerative diseases is highly dependent on mouse models Classical methods to assess the visual function of animals such as electroretinogram ERG which measures electrical responses in the retina do not address connections between the eye and brain or visual perception by the visual system ...

DESCRIPTION provided by applicant The prevalence of food allergy has been dramatically increasing for the last few decades Food Allergy and Anaphylaxis Network www foodallergy org estimates that up to million Americans have food allergies Six to eight percent of children under the age of three have food allergies and nearly four percent of adults have them Signs and symptoms of food all ...

DESCRIPTION provided by applicant SARCOIDOSIS DIAGNOSTIC TESTING LLC is a medical diagnostics company developing a diagnostic blood test for sarcoidosis Sarcoidosis is a multisystem granulomatous disorder that affects per people per year in the U S and disproportionately affects African Americans and women Sarcoidosis can lead to advanced pulmonary fibrosis pulmonary hyperte ...

DESCRIPTION provided by applicant Heroin and related opioids are highly addictive drugs known for their analgesic properties Since the number of heroin users in the United States has skyrocketed reaching epidemic levels Abuse of prescription opioid pain relievers oxycodone Oxycotin and hydrocodone Vicodin which are known gateway drugs to heroin has also increased dramatically Beca ...

DESCRIPTION provided by applicant Therapeutics is focused on the development of adjuvant systems with desired immune activities for targeted indications The Companyandapos s immune stimulatory adjuvant platform builds on combinatorial use of immune agonists with distinct immune targets and mechanisms of action for the generation of therapeutic immune responses Critical to this platform techno ...

DESCRIPTION provided by applicant Hazardous compounds in waters and soils are subject to a complex dynamic web of interactions among physical chemical and biological constituents in the natural environment Computational modeling has been proven indispensable to hazardous substances remediation particularly integrated modeling of pollutant hydrogeological fate and transport For the first t ...