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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. New piperazines effecting Abeta oligomer displacement from neuronal receptors

    SBC: COGNITION THERAPEUTICS, INC.            Topic: NIA

    DESCRIPTION provided by applicant Cognition Therapeutics Inc andapos s mission is to develop effective therapeutics for Alzheimerandapos s disease Recent scientific discoveries have identified oligomers of the brain protein Abeta as toxic culprits in the disease process Cognition has discovered therapeutic molecules that displace Abeta oligomers from neurons and block the downstream pathol ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Non-Invasive, Highly Specific Detection of Oxytocin in Biological Fluids

    SBC: GINER INC            Topic: NICHD

    DESCRIPTION provided by applicant Non Invasive Highly Specific Detection of Oxytocin in Biological Fluids Oxytocin a neuropeptide hormone plays an important role in a variety of complex social behaviors including affiliation sexual behavior and aggression It is best known for its role to facilitate the birth process through induction of myometrial muscle contractions However recent studi ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Novel Medical Food for the Management of Iron Deficiency Anemia

    SBC: CHYNA, LLC            Topic: NIDDK

    DESCRIPTION provided by applicant We will perform a clinical study to test a novel patented medical food to manage iron deficiency anemia The project is significant because it addresses the number one nutritional disorder in the world and a health problem on the global scale that is second only to tuberculosis in cost worldwide Estimates are that approximately billion people more than ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Novel therapies for inherited muscle diseases

    SBC: Medosome Biotec, LLC            Topic: NIAMS

    DESCRIPTION provided by applicant The pursuit of novel therapies informed by the astounding advances in biomedical science of the past half century has been fruitful for many disorders However inherited muscle diseases such as muscular dystrophy remain stubbornly resistant to sophisticated molecular approaches to therapy A few therapies are finally edging towards approval but it has become ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Oscillated Needle System to Reduce Stress, Pain Response, Heel Damage and Developmental Harm from Recurring Heel Sticks in Neonates

    SBC: ACTUATED MEDICAL, INC.            Topic: NICHD

    DESCRIPTION provided by applicant This Phase I STTR in response to RFA HD andquot Non or Minimally Invasive Methods to Measure Biochemical Substances during Neonatal and Perinatal Patient Care and Researchandquot develops and tests Baby Gentle Stick BGS a handheld device to decrease the distress of repeat blood sampling in neonates BGS combines delivery of vibration induced ane ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Painless, Bloodless And Safe Glucose Sensing System For The Pediatric Intensive Care Unit

    SBC: Fluorometrix Biomedical Company            Topic: NICHD

    DESCRIPTION provided by applicant Studies in the pediatric intensive care unit PICU have shown that hypoglycemia hyperglycemia as well as swings in blood glucose levels are strongly associated with higher morbidity and mortality However tight glucose control has not been proven as effective In fact hypoglycemia was found to be a real danger Thus there is a need for more careful study ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Peptide Based Therapy for Lung Fibrosis

    SBC: Novici Biotech LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Fibroproliferative illnesses leading to organ fibrosis and failure are responsible for approximately of deaths in developed countries whether idiopathic triggered by environmental factors infections or genetics organ fibrosis results in significant morbidity and mortality Organ fibrosis is responsible for health care costs exceeding $ billion year ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Personalized dosing of dichloroacetate for the treatment of rare and common diseases

    SBC: Medosome Biotec, LLC            Topic: NICHD

    ABSTRACT SUMMARY Pyruvate dehydrogenase complex PDC deficiency PDCD is a rare disease of mitochondrial energy failure in which the life of expectancy of affected children is severely truncated Treatment of PDCD remains a serious unmet challenge There has never been a controlled trial of any intervention for PDCD thus there is no proven therapy for affected patients Dichloroacetate DCA ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Polar sampling and optimization of protein-ligand cocrystal structures

    SBC: Gfree Bio, LLC            Topic: NIGMS

    DESCRIPTION provided by applicant Gfree Bio proposes to collaborate with Professor Bajaj and his group at the University of Texas to develop a general and much more theoretically rigorous algorithm for fitting the ligand binding region of experimental protein ligand cocrystal structures Current methods and practices often lead to very poor geometries for the bound ligand This is a significant ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Portable and Automated Radiation Effects Test Structures for Advanced Technology Nodes

    SBC: MICROELECTRONICS RESEARCH DEVELOPMENT CORPORATION            Topic: DTRA16A003

    Micro-RDC will develop portable radiation effects test structures that scales to new process nodes. These structures will enable the investigation of the effects of radiation on the new technology from the material processing level as well as the circuit level. The production of the chosen structures and the development of software to extract the model parameters will form the framework. A suit ...

    STTR Phase I 2016 Department of DefenseDefense Threat Reduction Agency
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