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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Novel peptide for enhancing diabetic wound healing
SBC: SCARLESS LABORATORIES INC Topic: 200PROJECT SUMMARY/ABSTRACT Diabetes Mellitus (DM), a metabolic disorder characterized by defective insulin signaling and elevated blood glucose, has become a public health epidemic with half of the US population diagnosed with either DM or pre- diabetes. One of the most common and devastating sequelae of uncontrolled DM is the development of chronic non-healing wounds. An estimated 25% of diabetic p ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Development of a SYF2 antisense oligonucleotide treatment for ALS and FTD
SBC: ACURASTEM INC Topic: NIADevelopment of a SYF2 antisense oligonucleotide treatment for ALS and FTD Project Summary Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are complex diseases that result from many diverse genetic etiologies. Although therapeutic strategies that target specific causal mutations (e.g. C9ORF72 antisense oligonucleotides (ASOs)) may prove effective against individual forms of AL ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Rapid and high-contrast photothermal microscopy with a novel tunable ZGP source
SBC: TRESTLE OPTICS LLC Topic: 400Abstract. Natural products offer excellent sources of health-promoting medicines yet challenges in efficiently and economically sourcing these value-add bio-compounds have prevented their greater availability and promotion to public health. We address this problem by developing a novel image-based screening technology that offers highly sensitive, phenotypic bioassays of metabolite concentrations ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Ultra-broadband multimodal microscopy with a catadioptric lens
SBC: TRESTLE OPTICS LLC Topic: 400Abstract. Virtually all optical microscopes for biological imaging are based on refractive objective lenses. The performance of these lenses approaches the theoretical limit, however, their use is limited to the visible to near-infrared spectral range. Even within this range, their performance is only guaranteed over a relatively narrow range, and broadband use is invariably affected by chromatic ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
MagPAD: Magnetic Puncture, Access, and Delivery of Large Bore Devices to the Heart Via the Venous System
SBC: MaGPaD, LLC Topic: NHLBIProject Summary Minimally invasive cardio-thoracic approaches, such as transcatheter aortic valve replacement (TAVR), have recently overtaken traditional surgical methods due to significant reductions in procedural mortality, morbidity, and improved time to recovery. Transfemoral access of the heart via the femoral artery is the most common approach for delivery of large bore devices such as heart ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
DEVELOPMENT OF A SALIVARY ASSAY FOR MEASURING PERIODONTAL DISEASE ACTIVITY
SBC: CELLECTGEN, INC. Topic: NIDCRProject Summary / Abstract Periodontal disease (PD) is globally the most common chronic inflammatory disease in humans, which according to the Centers for Disease Control and Prevention (CDC) affect 47% of U.S. adults 30 years of age or older and rt60% of those over 65 years.1 Given that the course of PD is marked by a discontinuous pattern of disease activity and inactivity showing exacerbation a ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Humanized monoclonal antibodies to treat mucormycosis
SBC: VITALEX BIOSCIENCES, LLC Topic: NIAIDMucormycosis, caused by Mucorales fungi, is a life-threatening infection that occurs in patients immunocom- promised by diabetic ketoacidosis, neutropenia, corticosteroid use, and/or increased serum iron. Because of the rising prevalence of mucormycosis risk factors, the incidence of the infection has risen. The increased number of mucormycosis cases is highlighted by the recent epidemic seen amon ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Reducing the Risk and Economic burden of Recurrent stroke by improving medication adherence using a Novel SMART Pill CONTAINER, Cap, and Health Literacy Technologies
SBC: SANO HEALTHCARE CONSULTANTS, LLC Topic: NIAStroke is the leading cause of death and disability worldwide with the strongest disparity instrokes seen in Black middle-aged persons. Black persons have incidence rates of ischemicstroke that are 2- to 3-fold higher than Whites. Additionally, over 80% of stroke survivors willhave immediate and persistent weakness of their upper limb, leaving half of the persons with achronic disability and inabi ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
A mobile health framework for left ventricular end diastolic pressure diagnostics and monitoring.
SBC: AVENTUSOFT L.L.C. Topic: NHLBIPROJECT SUMMARY/ABSTRACT This SBIR Fast-Track project will develop a novel mobile health framework for left ventricular end diastolic pressure diagnostics and monitoring, using an innovative, non-invasive cardiac biosensor. Heart disease is the leading cause of death for men and women accounting for more than one-third (33.6%) of all U.S. deaths. The total costs associated with cardiovascular dise ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Wicked Smart Pad: Washable Sensorized Bedding for the Prevention and Detection of Moisture Events
SBC: Wicked Sheets, LLC Topic: NIAProject Summary/Abstract: Due to decreased mobility, deterioration in activities of daily living, and neurological decline that contributes to loss of bladder control, incontinence is a leading comorbidity for those individuals suffering from Alzheimer’s disease and related dementias (ADRD). Further, individuals with incontinence are susceptible to the development of pressure ulcers (PUs), with ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health