Award Data

A key bottleneck to be addressed in regenerative medicine is hypothermic preservation of cells and tissues, which has been shown to extend survival of cell and tissue-based therapies by decreasing ischemic effect. However, preservation technology is aged, toxic and less effective than desired with typical cell survival post-thaw below 50% and unreliable potency. Current technology greatly hinders ...

Trauma is the most common cause of death in ages 1-48. Uncontrolled hemorrhage in the torso is the leading cause of preventable death in military combatants and civilian trauma patients with otherwise survivable injuries. The prospects for survival from hemorrhage-induced traumatic cardiac arrest (HiTCA) are dismal with only about a 1% survival rate. Advances in endovascular technologies have led ...

Iron deficiency is one of the most common nutritional deficiencies in the United States. Left untreated, iron stores continue to deplete, resulting in iron deficiency anemia (IDA). Women undergoing basic military training are particularly susceptible to reduced and depleted iron stores. To-date, there are no point-of-care (POC) instruments for comprehensive, accurate determination of iron status. ...

Existing visual screening devices consist of illuminated test cards. By rotating the knob, images may be changed; however, once the system is loaded with cards it cannot be easily reconfigured. There are a limited number of cards that a unit can hold at one time, and it is impossible to change cards on the fly if a patients vision needs further investigation or if the clinician wants to do variabl ...

DoD requires a single, multiplexed, saliva-based diagnostic bioassay to determine multiorgan injury-relevant systemic toxicity. This assay should quantitatively-detect clinically relevant biomarkers in saliva and validate organ injury arising from chemical/xenobiotic exposure. Innosense LLC (ISL) is building on its proprietary carbon nanotube platform to construct Nano-Mos for detecting salivary b ...

Despite recent tremendous leaps in the development of new technologies for image recording, presentation, manipulation, 3D capabilities, and analysis, many vision exams are still performed using paper Snellen charts, paper color charts and Amsler grids. Current procedures are time consuming, labor intensive, potentially subject to transcription errors and test preparation, which may compromise the ...

Typical procedures for respirator masks sizing and protective fit test are time-consuming and user intensive, requiring taking anthropometricmeasurements of the wearer, sampling the wearers breathing zone and the use of specialized tools and equipment. The proposed softwareapp aims to quickly, accurately and automatically perform respirator mask sizing and predict protective fit using only 2D imag ...

Moby.Read is aa tablet-based speech recognition app that grade school students use to administer oral-reading fluency assessments in real-time. The app is intended to replace face-to-face oral reading assessments done by teachers, and to save time and increase the accuracy of the assessment. Through the teacher dashboard, Moby.Read will aggregate assessment results at the class and individual stud ...

Concierge is a platform for school administrators to discover and select education technology products to support school improvement. The intended users are principals, technology coaches, and curriculum directors who are responsible for selecting and implementing education technology in K–12 classrooms or schools. Concierge will include components to guide administrators through the product dis ...

This Phase I proposal describes the development an inexpensive, portable optical sensor to monitor indoor formaldehyde levels. The proposed instrument will be capable of detecting 0.05-5 ppm levels of formaldehyde in the presence of common interferents. Formaldehyde is used in manufacturing and is present in many building materials. There are significant health risks associated with even low level ...