Award Data

ABSTRACT Extra InningsUsing Serious Gaming andampthe Science of Baseball to Teach Science andampMathematics Due to the rapid advances in sciencetechnologyengineeringand mathematicsSTEMthe United States has been at the forefront of innovation and technology development in the health and biomedical fieldsHoweverthese continuing advances are in jeopardy as there is a growing national shortage of trai ...

Project Summary/AbstractThe overall goal of this project is to complete development of the unbound bilirubin (Bf) assay system for assessing the risk of neonatal bilirubin encephalopathy (kernicterus). This includes establishing a manufacturing process for the components of the assay (reagents, disposable test cartridge, reader), transferring the manufacturing process to a contract manufacturer, i ...

Over a quarter century of research has significantly improved our understanding of the circulating cardiovascular system and its cellular componentsHoweverstudy of the parallel lymphatic system has lagged far behindlimiting our understanding of this complex and potentially clinical beneficial networkThe lymphatic system is comprised of an extensive network of vessels and nodes that parallel the ve ...

AbstractIn this SBIR projectwe present EyeMarka set of advanced image analysis tools for automated computation of biomarkers for diabetic retinopathyDRusing retinal fundus imagesSpecificallywe will develop tools for computation of microaneurysmMAappearance and disappearance ratesjointly known as turnover ratesfor use as a biomarker in quantifying DR progression risk along with longitudinal analysi ...

Project Summary End Stage Renal DiseaseESRDaffects just overpeople in the United States and costs Medicare$billion annuallyIn center thrice weekly hemodialysis is the most commonly performed treatment for ESRDbut it suffers from pooryear survival ratesreduced patient quality of lifeand is costlyIn contrastfrequent hemodialysis has demonstratedyear survival rates similar to kidney transplant and ha ...

1. PROJECT SUMMARY/ABSTRACT Omniox is developing a unique oxygen delivery protein, OMX, as a treatment to preserve myocardial and peripheral organ function and significantly reduce morbidity after neonatal cardiopulmonary bypass (CPB) during surgical correction of congenital heart disease (CHD). Of the ~40,000 children born annually with CHD, ~10,000 require urgent surgery to repair heart defects. ...

Project Summary Phase Diagnostics is aiming to create the new gold standard diagnostic for the detection of sexually transmitted infectionsSTIsThe company aims to replace lab based assays for Chlamydia trachomatisCTand expand testing accessibility to previously unreachable settingsThe technology combines the ease of use and very low cost of rapid point of carePOCdiagnostics with the very high accu ...

Point of Care Rapid RNA test for HIV PhaseCrossLife Technologies IncProject Summary Abstract Current antibody point of care tests cannot distinguish between a motherandapos s and babyandapos s antibodies to detect if an infant has become infected with Human Immunodeficiency VirusHIVAccording to a recent WHO UNAIDS UNICEF reportonly a predictedpercent of babies born to HIV positive mothers obtained ...

AbstractBrain swelling is a serious complication of traumatic brain injuryTBIischemic stroke and other serious conditionsTBI and stroke afflictM andK persons per year in the US aloneThey are a costly health care burden and a devastating social burdenCurrent treatments for brain swelling are limited and generally ineffectivehighlighting the dramatic unmet need for better therapeuticsA better unders ...

Of the overpatients undergoing instrumented spinal fusion surgery each year in the United Statesoverultimately require a revision surgerythe majority of which are secondary to insufficient bone qualityBiomechanical problems associated with insufficient bone quality include pseudarthrosisinsufficiency fractures of the proximal adjacent vertebrasubsidence of any intervertebral implant graft construc ...