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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A decellularized porcine placenta matrix hydrogel for management of radiation-induced proctitis
SBC: Briopryme Biologics, Inc. Topic: 102PROJECT SUMMARY Radiation therapy is a widely used treatment modality for pelvic malignancies such as prostate and cervical cancer; however, the high doses needed to confer therapeutic benefit often inflict significant damage on the normal issue in and surrounding the radiation field. The most frequent complication of pelvic radiation is proctitis, which nearly all patients experience acutely and ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Audiom: Developing an Indoor Non-Visual Mapping System
SBC: XR NAVIGATION INC Topic: NEIProject Abstract Indoor navigation for blind and visually impaired individuals (BVIs) within unfamiliar locations is typically an incredibly anxiety-provoking and stressful experience for numerous reasons, e.g., inaccessible signage including directories and venue maps, and if braille signs do exist, they are difficult to find, lack directional information, and are useless to the BVIs who do not r ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Developing of a computer-based multimodal mind and body approach for mild cognitive decline
SBC: BRAIN THRIVE TECHNOLOGY LLC Topic: NIASummary Mild cognitive impairment (MCI) represents an intermediate state between normal aging and the diagnosis of clinically probable very early Alzheimer's disease (AD). Since MCI manifests before the onset of AD, it may be the optimal stage in which to intervene with preventative therapies for AD and age-related dementia before progressive neurological loss and irreversible cognitive impairment ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Fluorescence lifetime imaging device for 5-ALA-guided neurosurgery
SBC: HILIGHT SURGICAL, INC. Topic: 394PROJECT SUMMARY 5-ALA-induced PpIX fluorescence-guided surgery (FGS) enables real-time visualization of residual cancer tissue during resection of brain tumors. This addresses a critical need in surgical oncology as the ability to identify residual tumor leads to improvements in overall survival, whereas the sparing of normal tissue benefits the patient’s quality of life. Currently, surgeons vis ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Identification of Mixed NOP/mu partial agonists as lead compounds for treatment ofmethamphetamine use disorder
SBC: PHOENIX PHARMALABS, INC. Topic: NIDAAbstract Currently, clinically used drug abuse medications exist for treatment of addiction to opiates, alcohol, and nicotine, but not psychostimulants, such as methamphetamine (METH). Compounds that co-activate both nociceptin opioid peptide (NOP) and mu receptors have potential for treatment of drug abuse. In particular, buprenorphine, a partial mu agonist/kappa antagonist, which also acts as a ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Feasibility and design of a novel smartphone app to deliver blood pressure-lowering inspiratory muscle strength training
SBC: KLEIN BUENDEL, INC. Topic: NHLBIPROJECT SUMMARYHigh blood pressure (BP), particularly high systolic BP (SBP), is the major modifiable risk factor for cardiovascular diseases (CVD) and related conditions. Indeed, over 50% of all adults have above-normal SBP (≥120 mmHg), placing them at increased disease risk. In addition, these adults face ~$2000/year in excess medical expenses compared to their peers with normal BP. Rates of B ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Targeting glioblastoma with CM93, a novel EGFR inhibitor with exceptional brain penetration
SBC: CRIMSON BIOPHARM INC Topic: NCIPROJECT SUMMARY The epidermal growth factor receptor (EGFR) gene is mutated and/or amplified in majority of primary glioblastoma (GBM). While EGFR-mutant GBM cancer cells are dependent on EGFR signaling for survival, numerous small molecule EGFR tyrosine kinase inhibitors (TKIs) have failed to show efficacy in this disease. There are two main reasons for these failures: i) Many of these EGFR-TKIs ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
New Agents for the Treatment on Mycobacteria Avium Infections
SBC: Quercus Molecular Design, LLC Topic: NIAIDAbstract: Non-Tuberculosis Mycobacteria (NTM) are responsible for widespread, life threatening infections of the lungs, skin, lymphatic and hematological systems. The rapid, global spread of resistant organisms has significantly reduced the number of agents that can be used effectively to treat these infections. Of specific clinical relevance are the slow-growing Mycobacterium avium complex (MAC) ...
STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health -
Novel Treatment for Alcohol-associated Liver Disease
SBC: MITOTHERAPEUTIX, LLC Topic: 350Abstract The Specific Aim of this Phase I TTR proposal is to test the feasibility of our siRNA drug to ameliorate the pathology and progression of alcohol-associated liver disease (ALD). Alcohol consumption remains a leading cause of hepatic pathology worldwide and is one of the greatest sources of preventable morbidity and mortality. In the U.S., alcohol abuse impacts over 10 million individuals ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
AI/ML Aided Aviation Sensors for Cognitive and Decision Optimization
SBC: KRTKL INC. Topic: SOCOM23B001krtkl (“critical”) will conduct a Phase I Feasibility Study to identify the best approach for reducing aviator cognitive load by optimizing information delivery and decision-making based on a thorough analysis of existing platforms, sensors, data sources, and onboard compute resources. This information will be used to identify Artificial Intelligence and Machine Learning based algorithms for p ...
STTR Phase I 2023 Department of DefenseSpecial Operations Command