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SBC: AMELIA TECHNOLOGIES LLC Topic: NIEHS
Project Summary Skin is the first line of defense against the outside environment. When the skin barrier is breached by UV irradiation (UVR) or toxic chemicals, living cell layers including epidermal keratinocytes, melanocytes and dermal fibroblasts are subjected to DNA damage. If unrepaired, this damage can lead to photoaging and cutaneous carcinogenesis. In fact, skin cancer is by far the most c ...STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
Self-Supervised Training in Geospatial Applications with a Robust Hierarchical Vision Transformer (STAR)SBC: UNIVERSITY TECHNICAL SERVICES, INC. Topic: OSD22A001
Satellite Imagery in Geospatial Intelligence (GEOINT), in conjunction with imagery intelligence (IMINT), geospatial information, and other means of gaining intelligence, has greatly improved the potential of the warfighter and decision makers enabling them to gain a more comprehensive perspective, an in-depth understanding, and a cross-functional awareness of the operational environment. The Artif ...STTR Phase I 2022 Department of DefenseNational Geospatial-Intelligence Agency
SBC: L2 DIAGNOSTICS LLC Topic: NIAID
SUMMARY Arboviruses present a constant threat to human and animal health worldwide. They are transmitted by hematophagous arthropods, primarily mosquitoes. One of them, Aedes aegypti, is the primary vector of several widely spread arboviruses such as Zika, dengue and West Nile viruses, and for most of them, human-licensed vaccines do not exist or are suboptimal. These pathogens are transmitted int ...STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
SBC: KLEIN BUENDEL, INC. Topic: R
Project Summary/Abstract U.S. prison systems face sharply increased demands in caring for older people living in prisons. Alzheimerandapos;s Disease and related dementias (ADRD) are age-related diseases. Prison populations are over- represented by minority populations who experience disparities in prevalence and incidence of dementia. Prison health, social, and security staff perceive they lack th ...STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
Translating an In-Person Brief, Bystander Bullying Intervention (STAC) to a Technology-Based- Phase IISBC: KLEIN BUENDEL, INC. Topic: 102
While studies support the efficacy of comprehensive, school-wide interventions in reducing bullying, these types of programs can require significant time and financial resources for implementation, resulting in barriers to providing school-based bullying prevention, especially in low-income and rural communities. Additionally, although training bystanders to act as “defenders” on behalf of tar ...STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
SBC: KLEIN BUENDEL, INC. Topic: NICHD
Internet-based TRAC (i-TRAC): Interactive Emotion Regulation Skills Training to Improve AdolescentSexual Health Adolescence is a critical developmental period during which behavioral patterns are formed that have powerful influences on current and future health. This is particularly true for sexual behavior, which is affected by the biological changes of puberty as well as normative developmental ...STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
SBC: KLEIN BUENDEL, INC. Topic: 102
Physical activity (PA) is a modifiable risk factor for a number of preventable chronic diseases, including cardiovascular disease, strokes, obesity, and diabetes. These conditions constitute health disparities for African American men. Behavioral interventions have proven to be effective in promoting increases in physical activity. While behavior change programs have been shown to assist participa ...STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
SBC: BIOSYNESIS, INC. Topic: NIAID
Project Summary/Abstract Members of the Candida genus of fungi form part of the normal human microbiota but are also opportunistic pathogens capable of causing serious mucosal and systemic infections. Candida cells grow and divide in suspension (planktonic) cultures, but they also form resilient and drug resistant biofilms – organized, tightly- packed communities of cells that attach to surfaces ...STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
SBC: FRAMESHIFT LABS INC Topic: 172
Summary/Abstract Genomic sequencing is rapidly becoming a standard tool in diagnosing complex diagnostic cases, especially in critically ill newborns, and patients suffering from rare diseases. Current programs focused on addressing these cases utilise a team-based approach to identify, interpret and evaluate a patient’s genetic variants. These diverse teams include bioinformaticians, medical ge ...STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
SBC: ACADEMIC WEB PAGES, INC Topic: 104
Project Summary/Abstract (30 lines) In the United States, 15 million children and adolescents need psychological services; yet only one-third receive psychological services of any kind. Even fewer receive care that is consistent with evidence-based guidelines for best practices. This gap has widened dramatically with the negative effects of the COVID-19 pandemic on the mental health of children, c ...STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health