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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Optimized Platforms for Proper Glycosylation and Sialylation of Recombinant Human Butyrylcholinesterase (rBChE)

    SBC: ECHELON BIOSCIENCES, INC.            Topic: CBD192007

    Organophosphorus (OP) toxins and chemical warfare agents (CWA) are active nerve agents posing significant hazard for both soldiers and civilians. Butyrylcholinesterase (BChE) is a safe and effective bioscavenger that detoxifies OP and CWAs when injected either prophylactically or post-exposure; but a major technical problem has been producing a recombinant form of BChE with acceptable properties f ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  2. Nanosatellite Payloads for Tactical Intelligence, Surveillance, and Reconnaissance

    SBC: Skeyeon, Inc.            Topic: SOCOM193001

    Skeyeon, Inc. has developed all technologies necessary to orbit an Earth Observation, EO, satellite at 250 km, developing a vehicle design; atomic oxygen resistant, low drag materials; high bandwidth, real-time RF links; electric propulsion for 3 year missions; and a 1 meter resolution optical telescope compressed into a 10 cm high framework. A constellation of 100’s-1,000’s of these vehicles ...

    SBIR Phase I 2020 Department of DefenseSpecial Operations Command
  3. Development of Small Molecule Therapeutics for Emerging Viral Agents

    SBC: ARISAN THERAPEUTICS INC            Topic: CBD192006

    Arenaviruses comprise a diverse group of Old (Africa) and New World (Americas) species. Several species are associated with hemorrhagic fever (HF) with case-fatality rates as high as 30%. Arenaviruses infection typically occurs via the mucosal route through contact with excretions of an infected rodents although direct human-to-human transmission may occur in clinical settings. Lassa arenavirus en ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  4. Non-Invasive Monitoring of Changes in Intracranial Pressure Due to Infections in the Central Nervous System

    SBC: Fenix Research Corporation            Topic: CBD192005

    Infections of the central nervous system (CNS) are associated with brain swelling and increased cerebral blood volume, as well as focal cerebral perfusion deficits, variable levels of cerebral blood flow and cerebral vasculitis. The net result is increased intracranial pressure (ICP) along with significant risk of brain tissue herniation and ischemic syndromes. ICP monitoring is critical in the ma ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  5. Development of a Non-invasive Negative Ophthalmodynamometer Capable of Measuring Intracranial Pressure in Humans

    SBC: Equinox Ophthalmic, Inc.            Topic: CBD192005

    Measurement of intracranial pressure (ICP) is essential in the diagnosis and management of numerous life threatening conditions. All current methods used clinically to measure ICP are invasive and require direct access to the cerebrospinal fluid giving them a significant side effect profile. The ability to measure ICP non-invasively would be a major milestone for patients. Spontaneous venous pulsa ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  6. Development of Small Molecule Therapeutics for Emerging Viral Agents

    SBC: ARISAN THERAPEUTICS INC            Topic: CBD192006

    Ebolavirus species including Zaire (EBOV), Sudan (SUDV) and Bundibugyo (BDBV) are responsible for severe hemorrhagic fever outbreaks with high case fatalities in Africa. Weaponized pathogens present an additional threat to the health protection of the warfighter and first-generation prophylactic and therapeutic medical countermeasures (MCMs) may prove inadequate in biodefense settings. Ebolaviruse ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  7. Self-contained Equipment Decontamination System (SCEDS)

    SBC: Integrated Solutions for Systems, Inc.            Topic: CBD192002

    The processes and systems required to decontaminate personnel have received much attention and several effective systems exist. However, decontamination of sensitive equipment, without damage or performance degradation, is a significantly different problem that has not been adequately solved. The wide variety of electronics, fabrics and structural materials together with the infinite variations in ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  8. Nanosatellite Payloads for Tactical Intelligence, Surveillance, and Reconnaissance

    SBC: Space Micro Inc.            Topic: SOCOM193001

    Space Micro will develop an innovative payload that can be hosted onboard a nanosatellite/ CubeSat bus, for the advancement of USSOCOM capabilities in rapid intelligence collection, surveillance, and reconnaissance (ISR). This R&D will improve and enhance capabilities in intelligence collection, surveillance, and reconnaissance from new spaceborne platforms.

    SBIR Phase I 2020 Department of DefenseSpecial Operations Command
  9. Nanosatellite Payloads for Tactical Intelligence, Surveillance, and Reconnaissance

    SBC: SA PHOTONICS, LLC            Topic: SOCOM193001

    CubeSats offer substantial reductions in operation and launch costs, while reducing time between request and employment of the capability. To address the USSOCOM needs, SA Photonics proposes an Infra-red Multispectral Imager for CubeSats (IMICS). IMICS collects diffraction-limited hyperspectral earth imagery, allowing identification of personnel, operating vessels / vehicles, structures and terrai ...

    SBIR Phase I 2020 Department of DefenseSpecial Operations Command
  10. A Multi-Branch Network for Automated VNIIRS Assessment of Motion Imagery

    SBC: TOYON RESEARCH CORPORATION            Topic: NGA191003

    Due to the lack of consistency in existing automated methods for assigning VNIIRS levels to motion imagery, and the overwhelming human resources required to manually assign levels, a new method of automated/semi-automated VNIIRS assessment is needed. In recent years, advancements in deep learning have provided solutions to previously intractable computer vision problems. In many cases, automated d ...

    SBIR Phase I 2019 Department of DefenseNational Geospatial-Intelligence Agency
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